Job Description Undefined Confidence 99.72% Date Thu Nov 13 08:26:15 GMT 2025 Rank 440 Aligned Residues 186 % Identity 15% Template c5symA_ PDB info PDB header: hydrolase/hydrolase inhibitor Chain: A: PDB Molecule: Acyl-protein thioesterase 1 PDBTitle: cocrystal structure of the human acyl protein thioesterase 1 with an isoform-selective inhibitor, ml348 PDB Entry: PDBe RCSB PDBj Resolution UNK

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		44	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.		.	.	80	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																				.													.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		Y	R	E	A	G	D	P	A	A	P	A	V	L	L	L	H	G	F	A	A	S	S	Y	M	W	R	D	V	I	E	A	L	A	D	.	G	Y	H	V	I	A	P	D	L	P	A	F	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																				.													.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																				.													.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		I	V	P	A	A	R	K	A	T	A	A	V	I	F	L	H	G	L	G	D	T	G	H	G	W	A	E	A	F	A	G	I	R	S	S	H	I	K	Y	I	C	P	H	A	P	V	R	P	V	T	L	N	M	N	V	A	M	P	S	W
Template Predicted Secondary structure
						90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.						.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Predicted Secondary structure		.	.	.	.																														.	.	.	.	.
Query Sequence		.	.	.	.	G	Y	T	E	A	P	A	R	G	Q	Y	D	Y	T	F	A	N	L	T	K	T	I	E	R	F	T	D	Q	L	.	.	.	.	.	K	L	T	R	Y	A	M	A	V	H	D	Y	G	A	P	V	G	W	R	L	A	L
Query Conservation		.	.	.	.																														.	.	.	.	.
Alig confidence		.	.	.	.				.	.																									.	.	.	.	.
Template Conservation									.	.
Template Sequence		F	D	I	I	G	L	S	.	.	P	D	S	Q	E	D	E	S	G	I	K	Q	A	A	E	N	I	K	A	L	I	D	Q	E	V	K	N	G	I	P	S	N	R	I	I	L	G	G	F	S	Q	G	G	A	L	S	L	Y	T	A	L
Template Predicted Secondary structure									.	.
		141	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200
Predicted Secondary structure
Query Sequence		A	H	P	S	R	I	T	A	I	I	S	Q	N	G	N	A	Y	E	E	G	L	S	A	G	W	E	P	I	R	K	Y	W	N	D	P	T	A	E	N	R	Q	A	L	S	D	F	P	T	P	A	S	I	K	W	Q	Y	V	E	G	V
Query Conservation
Alig confidence																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		T	T	Q	Q	K	L	A	G	V	T	A	L	S	C	W	L	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
		201	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260
Predicted Secondary structure
Query Sequence		S	D	T	S	L	V	A	P	D	A	Y	T	L	E	G	A	Q	I	L	R	P	G	M	A	D	I	Q	L	D	L	L	L	D	Y	A	T	N	V	E	Q	Y	P	A	F	Q	A	Y	F	R	E	Y	Q	P	P	L	L	A	V	W	G
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	L	R	A	S	F	P	Q	G	P	I	G	G	A	N	R	D	I	S	I	L	Q	C	H	G
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
		261	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280							.	.	.		.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310
Predicted Secondary structure																						.	.	.	.	.	.				.
Query Sequence		E	H	D	P	F	F	L	P	P	G	A	E	A	W	K	R	D	I	P	D	.	.	.	.	.	.	A	D	I	.	R	L	Y	D	T	G	H	F	A	L	E	T	H	S	E	V	I	I	P	T	I	R	Q	F	L	D	D
Query Conservation																						.	.	.	.	.	.				.
Alig confidence																						.	.	.	.	.	.				.
Template Conservation
Template Sequence		D	C	D	P	L	V	P	L	M	F	G	S	L	T	V	E	K	L	K	T	L	V	N	P	A	N	V	T	F	K	T	Y	E	G	M	M	H	S	S	C	Q	Q	E	M	M	D	V	K	Q	F	I	D	K	L	L	P	P
Template Predicted Secondary structure

No model constructed - rank, confidence too low

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Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
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