Job Description Undefined Confidence 99.67% Date Thu Nov 13 08:26:15 GMT 2025 Rank 269 Aligned Residues 236 % Identity 15% Template c5llsD_ PDB info PDB header: hydrolase Chain: D: PDB Molecule: Dipeptidyl peptidase 4 PDBTitle: ;porcine dipeptidyl peptidase iv in complex with 8-(3-aminopiperidin-1-yl)-7-[(2-bromophenyl)methyl]-1,3-dimethyl-2,3,6,7-tetrahydro-1h-purine-2,6-dione; PDB Entry: PDBe RCSB PDBj Resolution UNK

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		23	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50							.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.					70	.	.
Predicted Secondary structure																														.	.	.	.	.	.																				.	.	.	.
Query Sequence		R	A	S	A	A	P	Q	V	H	Y	R	V	E	Q	V	G	D	V	K	V	F	Y	R	E	A	G	D	P	.	.	.	.	.	.	A	A	P	A	V	L	L	L	H	G	F	A	A	S	S	Y	M	W	R	.	.	.	.	D	V	I
Query Conservation																														.	.	.	.	.	.																				.	.	.	.
Alig confidence																														.	.	.	.	.	.																				.	.	.	.
Template Conservation
Template Sequence		Q	D	V	Q	M	P	S	K	K	L	D	V	I	N	L	H	G	T	K	F	W	Y	Q	M	I	L	P	P	H	F	D	K	S	K	K	Y	P	L	L	I	E	V	Y	A	G	P	C	S	Q	K	V	D	T	V	F	R	L	S	W	A
Template Known Secondary structure		T	T														T	T										.	T	T			T	T	S												T	T
Template Predicted Secondary structure
		73	.	.	.			.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.						.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120			.	.	.
Predicted Secondary structure						.	.																				.	.	.	.	.																										.	.
Query Sequence		E	A	L	A	.	.	D	G	Y	H	V	I	A	P	D	L	P	A	F	G	Y	T	E	A	P	.	.	.	.	.	A	R	G	Q	Y	D	Y	T	F	A	N	L	T	K	T	I	E	R	F	T	D	Q	L	K	L	.	.	T	R	Y
Query Conservation						.	.																				.	.	.	.	.																										.	.
Alig confidence						.	.																				.	.	.	.	.																										.	.
Template Conservation
Template Sequence		T	Y	L	A	S	T	E	N	I	I	V	A	S	F	D	G	R	G	S	G	Y	Q	G	D	K	I	M	H	A	I	N	R	R	L	G	T	F	E	V	E	D	Q	I	E	A	T	R	Q	F	S	K	M	G	F	V	D	D	K	R	I
Template Known Secondary structure							T	T										T	T		S	S	S						G	G	G	T	T		T	T	S																S	T	T
Template Predicted Secondary structure
		124	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.
Predicted Secondary structure
Query Sequence		A	M	A	V	H	D	Y	G	A	P	V	G	W	R	L	A	L	A	H	P	S	R	I	T	A	I	I	S	Q	N	G	N	A	Y	E	E	G	L	S	A	G	W	E	P	I	R	K	Y	W	N	D	P	T	A	E	N	R	Q	A	L
Query Conservation
Alig confidence																																																							.	.	.	.	.	.	.
Template Conservation																																																							.	.	.	.	.	.	.
Template Sequence		A	I	W	G	W	S	Y	G	G	Y	V	T	S	M	V	L	G	A	G	S	G	V	F	K	C	G	I	A	V	A	P	V	S	K	W	E	Y	Y	D	S	V	Y	T	E	R	Y	M	G	L	P	T	P	E	.	.	.	.	.	.	.
Template Known Secondary structure							T											T	T			S			S						S					G	G	G	S	B											S	S	T	T	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																							.	.	.	.	.	.	.
		184	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.
Predicted Secondary structure
Query Sequence		S	D	F	P	T	P	A	S	I	K	W	Q	Y	V	E	G	V	S	D	T	S	L	V	A	P	D	A	Y	T	L	E	G	A	Q	I	L	R	P	G	M	A	D	I	Q	L	D	L	L	L	D	Y	A	T	N	V	E	Q	Y	P	A
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	N	L	D	Y	Y	R	N	S	T
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	T						T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
		244	.	.	.	.	.	250	.	.		.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.						.	.	.	.	.	.	.	.	290	.	.		.	.	.	.
Predicted Secondary structure											.																														.	.	.	.	.												.
Query Sequence		F	Q	A	Y	F	R	E	Y	Q	.	P	P	L	L	A	V	W	G	E	H	D	P	F	F	L	P	P	G	A	E	A	W	K	R	D	I	P	D	A	.	.	.	.	.	D	I	R	L	Y	D	T	G	H	F	A	.	L	E	T	H
Query Conservation											.																														.	.	.	.	.												.
Alig confidence											.																														.	.	.	.	.												.
Template Conservation
Template Sequence		V	M	S	R	A	E	N	F	K	Q	V	E	Y	L	L	I	H	G	T	A	D	D	N	V	H	F	Q	Q	S	A	Q	L	S	K	A	L	V	D	A	G	V	D	F	Q	T	M	W	Y	T	D	E	D	H	G	I	A	S	N	M	A
Template Known Secondary structure		S	G	G	G	G	G	G	G	G	G	S								T	T		S	S	S		T													T	T									T	T			S	S			S
Template Predicted Secondary structure
		297	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.
Predicted Secondary structure
Query Sequence		S	E	V	I	I	P	T	I	R	Q	F	L	D	D	H	V	S	L	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		H	Q	H	I	Y	T	H	M	S	H	F	L	K	Q	C	F	S	L	P
Template Known Secondary structure																	T	T
Template Predicted Secondary structure

No model constructed - rank, confidence too low

---

Phyre is now FREE for commercial users!

All images and data generated by Phyre2 are free to use in any publication with acknowledgement

Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
© Structural Bioinformatics Group, Imperial College, London Michael Sternberg   Disclaimer Terms and Conditions		Phyre2 is part of Genome3D