Job Description Undefined Confidence 99.97% Date Thu Nov 13 08:26:15 GMT 2025 Rank 312 Aligned Residues 276 % Identity 12% Template c5efzA_ PDB info PDB header: hydrolase Chain: A: PDB Molecule: Homoserine O-acetyltransferase PDBTitle: monoclinic structure of the acetyl esterase mekb PDB Entry: PDBe RCSB PDBj Resolution UNK

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

36

.

.

.

40

.

.

.

.

.

.

.

.

.

50

.

.

.

.

.

.

.

.

.

60

.

.

.

.

.

.

.

.

.

70

.

.

.

.

.

.

.

.

.

80

.

.

.

.

.

.

.

Predicted Secondary structure

.

.

.

.

.

.

.

.

Query Sequence

Q

V

G

D

V

K

V

F

Y

R

E

A

G

D

P

A

A

P

.

.

.

A

V

L

L

L

H

G

F

A

A

S

S

Y

M

W

R

D

.

V

I

.

.

.

E

A

L

.

A

D

G

Y

H

V

I

A

P

D

L

P

Query Conservation

.

.

.

.

.

.

.

.

Alig confidence

.

.

.

.

.

.

.

.

Template Conservation

Template Sequence

C

M

P

E

C

L

L

A

V

A

V

H

G

A

L

N

A

D

K

S

N

A

I

L

V

P

T

W

Y

S

G

T

S

K

A

M

E

Q

I

Y

I

G

E

G

R

A

L

D

P

S

K

Y

C

I

I

V

V

N

Q

I

Template Known Secondary structure

S

S

T

T

S

T

T

B

S

T

T

S

S

B

T

T

T

.

.

T

Template Predicted Secondary structure

88

.

90

.

.

.

.

.

.

.

.

.

100

.

.

.

.

.

.

.

.

.

110

.

.

.

.

.

.

.

.

.

120

.

.

.

.

.

.

.

.

.

130

.

.

.

.

.

.

.

Predicted Secondary structure

.

.

.

.

.

.

.

.

.

.

Query Sequence

A

F

G

Y

T

E

A

P

A

R

G

Q

Y

D

Y

.

.

.

.

.

.

.

.

T

F

A

N

L

T

K

T

I

E

R

F

T

.

D

Q

L

K

L

T

R

Y

.

A

M

A

V

H

D

Y

G

A

P

V

G

W

R

Query Conservation

.

.

.

.

.

.

.

.

.

.

Alig confidence

.

.

.

.

.

.

.

.

.

.

Template Conservation

Template Sequence

G

N

G

L

S

S

S

A

S

N

T

G

G

S

L

A

G

P

G

F

A

N

V

R

I

G

D

D

V

S

A

Q

H

T

L

L

T

E

Y

F

G

I

E

S

L

A

L

V

V

G

G

S

M

G

A

Q

Q

T

Y

E

Template Known Secondary structure

T

S

S

S

S

S

T

T

T

G

G

G

S

G

G

G

B

S

T

Template Predicted Secondary structure

138

.

140

.

.

.

.

.

.

.

.

.

150

.

.

.

.

.

.

.

.

.

160

.

.

.

.

.

.

.

.

.

170

.

.

.

.

.

.

.

.

.

180

.

.

.

.

.

.

Predicted Secondary structure

.

.

.

.

.

.

.

.

.

.

.

Query Sequence

L

A

L

A

H

P

S

R

I

T

A

I

I

S

Q

N

G

N

A

Y

E

E

G

L

S

A

G

W

E

P

I

R

K

Y

W

N

D

P

T

A

E

N

.

.

.

.

.

.

.

.

.

.

.

R

Q

A

L

S

D

F

Query Conservation

.

.

.

.

.

.

.

.

.

.

.

Alig confidence

.

.

.

.

.

.

.

.

.

.

.

Template Conservation

Template Sequence

W

A

V

R

Y

P

D

F

V

K

R

A

A

A

I

A

G

T

A

R

N

S

E

H

D

F

L

F

T

E

I

L

I

E

A

I

T

T

D

P

A

F

Q

A

G

L

Y

R

S

S

S

A

V

A

A

G

L

E

R

H

Template Known Secondary structure

S

T

T

T

B

S

S

S

B

T

S

G

G

G

G

G

G

T

S

G

G

G

G

Template Predicted Secondary structure

187

.

.

190

.

.

.

.

.

.

.

.

.

200

.

.

.

.

.

.

.

.

.

210

.

.

.

.

.

.

.

.

.

220

.

.

.

.

.

.

.

.

.

230

.

.

.

.

.

.

.

.

.

240

Predicted Secondary structure

.

.

.

.

.

.

Query Sequence

P

T

P

A

S

I

K

W

Q

Y

V

E

G

V

S

D

T

S

.

.

.

.

.

.

L

V

A

P

D

A

Y

T

L

E

G

A

Q

I

L

R

P

G

M

A

D

I

Q

L

D

L

L

L

D

Y

A

T

N

V

E

Q

Query Conservation

.

.

.

.

.

.

Alig confidence

.

.

.

.

.

.

Template Conservation

Template Sequence

A

K

L

W

T

L

M

G

W

S

P

E

F

F

R

T

G

R

H

K

A

L

G

F

E

S

M

Q

M

F

V

D

G

F

M

K

R

Y

F

A

P

M

D

P

N

N

L

L

T

M

A

W

K

W

Q

R

G

D

V

S

Template Known Secondary structure

S

T

T

T

T

S

S

T

T

S

T

B

G

G

Template Predicted Secondary structure

241

.

.

.

.

.

.

.

.

250

.

.

.

.

.

.

.

.

.

260

.

.

.

.

.

.

.

.

.

270

.

.

.

.

.

.

.

.

.

280

.

.

.

.

.

.

.

.

.

290

.

.

.

Predicted Secondary structure

.

.

.

.

.

.

.

Query Sequence

.

.

.

Y

P

A

F

Q

A

Y

F

R

E

Y

Q

P

P

L

L

A

V

W

G

E

H

D

P

F

F

L

P

P

G

A

E

A

W

K

R

D

I

P

D

A

D

I

R

.

L

Y

D

.

T

G

H

F

A

L

.

.

Query Conservation

.

.

.

.

.

.

.

Alig confidence

.

.

.

.

.

.

.

Template Conservation

Template Sequence

R

H

T

G

G

D

L

A

K

A

L

G

R

I

K

A

K

T

Y

V

M

P

I

S

H

D

Q

F

F

T

V

D

D

C

L

S

E

Q

K

M

I

P

N

S

E

F

R

P

L

R

S

I

D

G

H

L

G

L

F

G

Template Known Secondary structure

G

G

G

T

T

T

T

S

B

T

T

S

S

S

T

T

S

T

T

B

T

T

G

G

G

G

G

G

S

Template Predicted Secondary structure

294

.

.

.

.

.

300

.

.

.

.

.

.

.

.

.

310

.

Predicted Secondary structure

.

.

Query Sequence

.

.

E

T

H

S

E

V

I

I

P

T

I

R

Q

F

L

D

D

H

Query Conservation

.

.

Alig confidence

.

.

Template Conservation

Template Sequence

T

D

A

Q

M

L

D

Q

L

D

A

H

L

A

E

L

L

S

S

P

Template Known Secondary structure

T

S

.

Template Predicted Secondary structure

No model constructed - rank, confidence too low

---

Phyre is now FREE for commercial users!

All images and data generated by Phyre2 are free to use in any publication with acknowledgement

Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
© Structural Bioinformatics Group, Imperial College, London Michael Sternberg   Disclaimer Terms and Conditions		Phyre2 is part of Genome3D