Job Description Undefined Confidence 99.93% Date Thu Nov 13 08:26:15 GMT 2025 Rank 9 Aligned Residues 294 % Identity 22% Template c5ai6A_ PDB info PDB header: hydrolase Chain: A: PDB Molecule: BIFUNCTIONAL EPOXIDE HYDROLASE 2 PDBTitle: ligand complex structure of soluble epoxide hydrolase PDB Entry: PDBe RCSB PDBj Resolution UNK Model Dimensions (Å) X:47.065 Y:55.823 Z:60.903

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

15

.

.

.

.

20

.

.

.

.

.

.

.

.

.

30

.

.

.

.

.

.

.

.

.

40

.

.

.

.

.

.

.

.

.

50

.

.

.

.

.

.

.

.

.

60

.

.

.

.

.

.

.

.

.

70

.

.

.

.

Predicted Secondary structure

Query Sequence

R

G

D

H

A

P

G

G

R

A

S

A

A

P

Q

V

H

Y

R

V

E

Q

V

G

D

V

K

V

F

Y

R

E

A

G

D

P

A

A

P

A

V

L

L

L

H

G

F

A

A

S

S

Y

M

W

R

D

V

I

E

A

Query Conservation

Alig confidence

.

.

Template Conservation

.

.

Template Sequence

N

T

P

A

P

L

P

T

S

C

N

P

S

D

M

S

H

G

Y

V

T

V

K

P

R

V

R

L

H

F

V

E

L

G

S

.

.

G

P

A

V

C

L

C

H

G

F

P

E

S

W

Y

S

W

R

Y

Q

I

P

A

Template Predicted Secondary structure

.

.

75

.

.

.

.

80

.

.

.

.

.

.

.

.

.

90

.

.

.

.

.

.

.

.

.

100

.

.

.

.

.

.

.

.

.

110

.

.

.

.

.

.

.

.

.

120

.

.

.

.

.

.

.

.

.

130

.

.

.

Predicted Secondary structure

.

Query Sequence

L

A

D

.

G

Y

H

V

I

A

P

D

L

P

A

F

G

Y

T

E

A

P

A

R

G

Q

Y

D

Y

T

F

A

N

L

T

K

T

I

E

R

F

T

D

Q

L

K

L

T

R

Y

A

M

A

V

H

D

Y

G

A

P

Query Conservation

.

Alig confidence

.

.

Template Conservation

.

Template Sequence

L

A

Q

A

G

Y

R

V

L

A

M

D

M

K

G

Y

G

E

S

S

A

P

P

.

E

I

E

E

Y

C

M

E

V

L

C

K

E

M

V

T

F

L

D

K

L

G

L

S

Q

A

V

F

I

G

H

D

W

G

G

M

Template Predicted Secondary structure

.

134

.

.

.

.

.

140

.

.

.

.

.

.

.

.

.

150

.

.

.

.

.

.

.

.

.

160

.

.

.

.

.

.

Predicted Secondary structure

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

Query Sequence

V

G

W

R

L

A

L

A

H

P

S

R

I

T

A

I

I

S

Q

N

G

N

A

Y

E

E

G

L

S

A

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

G

W

E

Query Conservation

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

Alig confidence

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

Template Conservation

Template Sequence

L

V

W

Y

M

A

L

F

Y

P

E

R

V

R

A

V

A

S

L

N

T

P

F

I

P

A

N

P

N

M

S

P

L

E

S

I

K

A

N

P

V

F

D

Y

Q

L

Y

F

Q

E

P

G

V

A

E

A

E

L

E

Q

Template Predicted Secondary structure

167

.

.

170

.

.

.

.

.

.

.

.

.

180

.

.

.

.

.

.

.

.

.

190

.

.

.

.

.

.

.

.

.

200

.

.

.

.

.

.

.

.

.

210

.

.

.

.

.

.

.

.

.

220

.

.

.

.

.

.

Predicted Secondary structure

Query Sequence

P

I

R

K

Y

W

N

D

P

T

A

E

N

R

Q

A

L

S

D

F

P

T

P

A

S

I

K

W

Q

Y

V

E

G

V

S

D

T

S

L

V

A

P

D

A

Y

T

L

E

G

A

Q

I

L

R

P

G

M

A

D

I

Query Conservation

Alig confidence

Template Conservation

Template Sequence

N

L

S

R

T

F

K

S

L

F

R

A

S

D

E

S

V

L

S

M

H

K

V

C

E

A

G

G

L

F

V

N

S

P

E

E

P

S

L

S

R

M

V

T

E

E

E

I

Q

F

Y

V

Q

Q

F

K

K

S

G

F

Template Predicted Secondary structure

227

.

.

230

.

.

.

.

.

.

.

.

.

240

.

.

.

.

.

.

.

.

.

250

.

.

.

.

.

.

.

.

.

260

.

.

.

.

.

.

.

.

.

270

.

.

.

.

.

.

.

.

.

280

.

.

.

.

.

Predicted Secondary structure

.

Query Sequence

Q

L

D

L

L

L

D

Y

A

T

N

V

E

Q

Y

P

A

F

Q

A

Y

F

R

E

Y

Q

P

P

L

L

A

V

W

G

E

H

D

P

F

F

L

P

P

G

A

E

A

W

K

R

D

I

P

D

A

D

I

.

R

L

Query Conservation

.

Alig confidence

.

Template Conservation

Template Sequence

R

G

P

L

N

W

Y

R

N

M

E

R

N

W

K

W

A

C

K

S

L

G

R

K

I

L

I

P

A

L

M

V

T

A

E

K

D

F

V

L

V

P

Q

M

S

Q

H

M

E

D

W

I

P

H

L

K

R

G

H

I

Template Predicted Secondary structure

286

.

.

.

290

.

.

.

.

.

.

.

.

.

300

.

.

.

.

.

.

.

.

.

310

.

Predicted Secondary structure

Query Sequence

Y

D

T

G

H

F

A

L

E

T

H

S

E

V

I

I

P

T

I

R

Q

F

L

D

D

H

Query Conservation

Alig confidence

Template Conservation

Template Sequence

E

D

C

G

H

W

T

Q

M

D

K

P

T

E

V

N

Q

I

L

I

K

W

L

D

S

D

Template Predicted Secondary structure

---

Phyre is now FREE for commercial users!

All images and data generated by Phyre2 are free to use in any publication with acknowledgement

Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
© Structural Bioinformatics Group, Imperial College, London Michael Sternberg   Disclaimer Terms and Conditions		Phyre2 is part of Genome3D