Job Description Undefined Confidence 99.97% Date Thu Nov 13 08:26:15 GMT 2025 Rank 69 Aligned Residues 286 % Identity 18% Template c4dlnB_ PDB info PDB header: hydrolase Chain: B: PDB Molecule: Putative hydrolase PDBTitle: crystal structure of the cftr inhibitory factor cif with the d129s mutation PDB Entry: PDBe RCSB PDBj Resolution UNK

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

23

.

.

.

.

.

.

30

.

.

.

.

.

.

.

.

.

40

.

.

.

.

.

.

.

.

.

50

.

.

.

.

.

.

.

.

.

60

.

.

.

.

.

.

.

.

.

70

.

.

.

.

.

.

.

.

.

80

.

.

Predicted Secondary structure

Query Sequence

R

A

S

A

A

P

Q

V

H

Y

R

V

E

Q

V

G

D

V

K

V

F

Y

R

E

A

G

D

P

A

A

P

A

V

L

L

L

H

G

F

A

A

S

S

Y

M

W

R

D

V

I

E

A

L

A

D

G

Y

H

V

I

Query Conservation

Alig confidence

.

.

Template Conservation

.

.

Template Sequence

E

F

P

V

P

N

G

F

E

S

A

Y

R

E

V

D

G

V

K

L

H

Y

V

K

G

G

Q

.

.

G

P

L

V

M

L

V

H

G

F

G

Q

T

W

Y

E

W

H

Q

L

M

P

E

L

A

K

R

F

T

V

I

Template Predicted Secondary structure

.

.

83

.

.

.

.

.

.

90

.

.

.

.

.

.

.

.

.

100

.

.

.

.

.

.

.

.

.

110

.

.

.

.

.

.

.

.

.

120

.

.

.

.

.

.

.

.

.

130

.

.

.

.

.

.

.

.

.

140

.

Predicted Secondary structure

.

Query Sequence

A

P

D

L

P

A

F

G

Y

T

E

A

P

A

R

G

Q

Y

D

Y

T

F

A

N

L

T

K

T

I

E

R

F

T

D

Q

L

K

L

T

R

.

Y

A

M

A

V

H

D

Y

G

A

P

V

G

W

R

L

A

L

A

Query Conservation

.

Alig confidence

.

.

.

.

Template Conservation

.

.

.

Template Sequence

A

P

D

L

P

G

L

G

Q

S

E

P

P

K

T

G

.

.

.

Y

S

G

E

Q

V

A

V

Y

L

H

K

L

A

R

Q

F

S

P

D

R

P

F

D

L

V

A

H

S

I

G

I

W

N

T

Y

P

M

V

V

K

Template Predicted Secondary structure

.

.

.

142

.

.

.

.

.

.

.

150

.

.

.

.

.

.

.

.

.

160

.

.

.

.

.

.

.

.

.

170

.

.

.

.

.

.

.

.

.

180

.

.

.

.

.

.

.

.

.

190

.

.

.

Predicted Secondary structure

.

.

.

.

.

.

.

.

Query Sequence

H

P

S

R

I

T

A

I

I

S

Q

N

G

N

.

.

.

.

.

.

.

.

A

Y

E

E

G

L

S

A

G

W

E

P

I

R

K

Y

W

N

D

P

T

A

E

N

R

Q

A

L

S

D

F

P

T

P

A

S

I

K

Query Conservation

.

.

.

.

.

.

.

.

Alig confidence

.

.

.

.

.

.

.

.

Template Conservation

Template Sequence

N

Q

A

D

I

A

R

L

V

Y

M

E

A

P

I

P

D

A

R

I

Y

R

F

P

A

F

T

A

Q

G

E

S

L

V

W

H

F

S

F

F

A

A

D

D

R

L

A

E

T

L

I

A

G

K

E

R

F

F

L

E

Template Predicted Secondary structure

194

.

.

.

.

.

200

.

.

.

.

.

.

.

.

.

210

.

.

.

.

.

.

.

.

.

220

.

.

.

.

.

.

.

.

.

230

.

.

.

.

.

.

.

.

.

240

.

.

.

.

.

.

.

.

.

250

.

.

.

Predicted Secondary structure

Query Sequence

W

Q

Y

V

E

G

V

S

D

T

S

L

V

A

P

D

A

Y

T

L

E

G

A

Q

I

L

R

P

G

M

A

D

I

Q

L

D

L

L

L

D

Y

A

T

N

V

E

Q

Y

P

A

F

Q

A

Y

F

R

E

Y

Q

P

Query Conservation

Alig confidence

.

.

Template Conservation

.

.

Template Sequence

H

F

I

K

S

H

A

S

N

T

E

V

F

S

E

R

L

L

D

L

Y

A

R

S

Y

A

K

P

H

S

L

N

A

S

F

E

Y

Y

R

A

L

N

E

S

V

R

Q

N

A

E

L

A

K

T

.

.

R

L

Q

M

Template Predicted Secondary structure

.

.

254

.

.

.

.

.

260

.

.

.

.

.

.

.

.

.

270

.

.

.

.

.

.

.

.

.

280

.

.

.

.

.

.

.

.

.

290

.

.

.

.

.

.

.

.

.

300

.

.

.

.

.

.

.

.

.

310

.

.

Predicted Secondary structure

.

Query Sequence

P

L

L

A

V

W

G

E

H

D

P

F

F

L

P

P

G

A

E

A

W

K

R

D

I

P

D

A

D

I

.

R

L

Y

D

T

G

H

F

A

L

E

T

H

S

E

V

I

I

P

T

I

R

Q

F

L

D

D

H

V

Query Conservation

.

Alig confidence

.

Template Conservation

Template Sequence

P

T

M

T

L

A

G

G

G

H

G

G

M

G

T

F

Q

L

E

Q

M

K

A

Y

A

E

D

V

E

G

H

V

L

P

G

C

G

H

W

L

P

E

E

C

A

A

P

M

N

R

L

V

I

D

F

L

S

R

G

R

Template Predicted Secondary structure

313

.

.

Predicted Secondary structure

Query Sequence

S

L

H

Query Conservation

Alig confidence

Template Conservation

Template Sequence

H

H

H

Template Predicted Secondary structure

No model constructed - rank, confidence too low

---

Phyre is now FREE for commercial users!

All images and data generated by Phyre2 are free to use in any publication with acknowledgement

Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
© Structural Bioinformatics Group, Imperial College, London Michael Sternberg   Disclaimer Terms and Conditions		Phyre2 is part of Genome3D