Job Description Undefined Confidence 99.76% Date Thu Nov 13 08:26:15 GMT 2025 Rank 262 Aligned Residues 239 % Identity 15% Template c3zwqA_ PDB info PDB header: hydrolase Chain: A: PDB Molecule: ALPHA/BETA HYDROLASE FOLD-3 DOMAIN PROTEIN PDBTitle: hyperthermophilic esterase from the archeon pyrobaculum calidifontis PDB Entry: PDBe RCSB PDBj Resolution UNK

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		30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.				.	.	.	.	.	.	.	60	.	.				.	.	.	.	.	.	.	70	.	.	.	.	.	.	.			.	.	80	.
Predicted Secondary structure																									.	.	.											.	.	.																.	.
Query Sequence		V	H	Y	R	V	E	Q	V	G	D	V	K	V	F	Y	R	E	A	G	D	P	A	A	.	.	.	P	A	V	L	L	L	H	G	F	A	.	.	.	A	S	S	Y	M	W	R	D	V	I	E	A	L	A	D	.	.	G	Y	H	V
Query Conservation																									.	.	.											.	.	.																.	.
Alig confidence																									.	.	.											.	.	.																.	.
Template Conservation
Template Sequence		V	E	D	I	T	I	P	G	R	G	G	P	I	R	A	R	V	Y	R	P	R	D	G	E	R	L	P	A	V	V	Y	Y	H	G	G	G	F	V	L	G	S	V	E	T	H	D	H	V	C	R	R	L	A	N	L	S	G	A	V	V
Template Known Secondary structure										T	T											S			S	S										S	T	T	T	S			T	G	G	G
Template Predicted Secondary structure
		82	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.
Predicted Secondary structure
Query Sequence		I	A	P	D	L	P	A	F	G	Y	T	E	A	P	A	R	G	Q	Y	D	Y	T	F	A	N	L	T	K	T	I	E	R	F	T	D	Q	L	K	L	T	R	Y	A	M	A	V	H	D	Y	G	A	P	V	G	W	R	L	A	L	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	S	V	D	Y	R	L	A	P	E	H	K	F	P	A	A	V	E	D	A	Y	D	A	A	K	W	V	A	D	N	Y	D	D	K	L	G	V	D	N	G	K	I	A	V	A	G	D	S	A	G	G	N	L	A	A	V	T	A	I	M
Template Known Secondary structure									T	T	T	S		T	T																T			.			T												T
Template Predicted Secondary structure
		142	.	.	.					.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170						.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.
Predicted Secondary structure						.	.	.	.																										.	.	.	.	.
Query Sequence		H	P	S	R	.	.	.	.	I	T	A	I	I	S	Q	N	G	N	A	Y	E	E	G	L	S	A	G	W	E	P	I	R	K	.	.	.	.	.	Y	W	N	D	P	T	A	E	N	R	Q	A	L	S	D	F	P	T	P	A	S	I
Query Conservation						.	.	.	.																										.	.	.	.	.
Alig confidence						.	.	.	.																										.	.	.	.	.
Template Conservation
Template Sequence		A	R	D	R	G	E	S	F	V	K	Y	Q	V	L	I	Y	P	A	V	N	L	T	G	S	P	T	V	S	R	V	E	Y	S	G	P	E	Y	V	I	L	T	A	D	L	M	A	W	F	G	R	Q	Y	F	S	K	P	Q	D	A	L
Template Known Secondary structure					T	T											S						S	S									T		S	G	G	G		S	S														S	S	G	G	G	G	G
Template Predicted Secondary structure
		193	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.
Predicted Secondary structure
Query Sequence		K	W	Q	Y	V	E	G	V	S	D	T	S	L	V	A	P	D	A	Y	T	L	E	G	A	Q	I	L	R	P	G	M	A	D	I	Q	L	D	L	L	L	D	Y	A	T	N	V	E	Q	Y	P	A	F	Q	A	Y	F	R	E	Y	Q
Query Conservation
Alig confidence																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		S	P	Y	A	S	P	I	F	A	D	L	S	N	L	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		S	T	T	T		G	G	G	S			T	T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
		253	.	.	.	.	.	.	260	.	.	.	.	.	.	.			.	.	270	.	.	.	.	.	.	.	.	.	280	.		.	.		.	.	.	.	.	.	290	.	.	.							.	.	.	.	.	.	300	.	.
Predicted Secondary structure																	.	.															.			.											.	.	.	.	.	.
Query Sequence		P	P	L	L	A	V	W	G	E	H	D	P	F	F	L	.	.	P	P	G	A	E	A	W	K	R	D	I	P	D	A	.	D	I	.	R	L	Y	D	T	G	H	F	A	L	.	.	.	.	.	.	E	T	H	S	E	V	I	I	P
Query Conservation																	.	.															.			.											.	.	.	.	.	.
Alig confidence		.															.	.															.			.											.	.	.	.	.	.
Template Conservation		.
Template Sequence		.	P	A	L	V	I	T	A	E	Y	D	P	L	R	D	E	G	E	L	Y	A	H	L	L	K	T	R	G	V	R	A	V	A	V	V	R	Y	N	G	V	I	H	G	F	V	N	F	Y	P	I	L	L	E	E	G	R	E	A	V	S
Template Known Secondary structure		.	.										T	T														T	T							.							T	T	G	G	G	G	T	T	T		.
Template Predicted Secondary structure		.
		303	.	.	.	.	.	.	310	.	.	.	.
Predicted Secondary structure
Query Sequence		T	I	R	Q	F	L	D	D	H	V	S	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	I	A	A	S	I	K	S	M	A	V	A
Template Known Secondary structure										T	T	T
Template Predicted Secondary structure

No model constructed - rank, confidence too low

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Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
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