Job Description Undefined Confidence 99.82% Date Thu Nov 13 08:26:15 GMT 2025 Rank 383 Aligned Residues 233 % Identity 13% Template c3v9aA_ PDB info PDB header: hydrolase activator Chain: A: PDB Molecule: Esterase/lipase PDBTitle: crystal structure of esterase/lipase from uncultured bacterium PDB Entry: PDBe RCSB PDBj Resolution UNK

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		25	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.		.	.	50	.	.	.	.	.	.	.	.	.	60				.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.			.
Predicted Secondary structure																									.														.	.	.																		.	.
Query Sequence		S	A	A	P	Q	V	H	Y	R	V	E	Q	V	G	D	V	K	V	F	Y	R	E	A	.	G	D	P	A	A	P	A	V	L	L	L	H	G	.	.	.	F	A	A	S	S	Y	M	W	R	D	V	I	E	A	L	A	D	.	.	G
Query Conservation																									.														.	.	.																		.	.
Alig confidence																									.														.	.	.																		.	.
Template Conservation
Template Sequence		K	A	A	D	D	I	Q	V	E	Q	V	T	V	A	G	C	A	A	E	W	V	R	A	P	G	C	Q	A	G	K	A	I	L	Y	L	H	G	G	G	Y	V	M	G	S	I	N	T	H	R	S	M	V	G	E	I	S	R	A	S	Q
Template Predicted Secondary structure
		79	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.		.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.
Predicted Secondary structure																																									.
Query Sequence		Y	H	V	I	A	P	D	L	P	A	F	G	Y	T	E	A	P	A	R	G	Q	Y	D	Y	T	F	A	N	L	T	K	T	I	E	R	F	T	D	Q	.	L	K	L	T	R	Y	A	M	A	V	H	D	Y	G	A	P	V	G	W	R
Query Conservation																																									.
Alig confidence																	.	.	.	.	.	.																			.
Template Conservation																	.	.	.	.	.	.
Template Sequence		A	A	A	L	L	L	D	Y	R	L	A	P	E	H	P	.	.	.	.	.	.	F	P	A	A	V	E	D	G	V	A	A	Y	R	W	L	L	D	Q	G	F	K	P	Q	H	L	S	I	S	G	D	S	A	G	G	G	L	V	L	A
Template Predicted Secondary structure																	.	.	.	.	.	.
		138	.	140	.	.	.	.	.					.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.
Predicted Secondary structure										.	.	.	.
Query Sequence		L	A	L	A	H	P	S	R	.	.	.	.	I	T	A	I	I	S	Q	N	G	N	A	Y	E	E	G	L	S	A	G	W	E	P	I	R	K	Y	W	N	D	P	T	A	E	N	R	Q	A	L	S	D	F	P	T	P	A	S	I	K
Query Conservation										.	.	.	.
Alig confidence										.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		V	L	V	S	A	R	D	Q	G	L	P	M	P	A	S	A	I	P	I	S	P	W	A	D	M	T	C	T	N	D	S	F	K	T	R	A	E	A	D	P	M	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
		194	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.			.	.	.	.	250	.
Predicted Secondary structure																																																						.	.
Query Sequence		W	Q	Y	V	E	G	V	S	D	T	S	L	V	A	P	D	A	Y	T	L	E	G	A	Q	I	L	R	P	G	M	A	D	I	Q	L	D	L	L	L	D	Y	A	T	N	V	E	Q	Y	P	A	F	Q	.	.	A	Y	F	R	E	Y
Query Conservation																																																						.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																					.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	I	N	K	M	A	A	R	Y	L	N	G	A	D	A	K	H	P	Y	A	S	P	N	F	A	N	L	K
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
		252	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.				.	.		.	.	.	.	.	.	290	.	.	.	.	.	.	.						.	.	300	.	.
Predicted Secondary structure																																.	.	.			.															.	.	.	.	.
Query Sequence		Q	P	P	L	L	A	V	W	G	E	H	D	P	F	F	L	P	P	G	A	E	A	W	K	R	D	I	P	D	A	.	.	.	D	I	.	R	L	Y	D	T	G	H	F	A	L	E	T	H	S	.	.	.	.	.	E	V	I	I	P
Query Conservation																																.	.	.			.															.	.	.	.	.
Alig confidence																																.	.	.			.															.	.	.	.	.
Template Conservation
Template Sequence		G	L	P	P	L	L	I	H	V	G	R	D	E	V	L	L	D	D	S	I	K	L	D	A	K	A	K	A	D	G	V	K	S	T	L	E	I	W	D	D	M	I	H	V	W	H	A	F	H	P	M	L	P	E	G	K	Q	A	I	V
Template Predicted Secondary structure
		303	.	.	.	.	.	.	310	.	.	.
Predicted Secondary structure
Query Sequence		T	I	R	Q	F	L	D	D	H	V	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	V	G	E	F	M	R	E	Q	W	A
Template Predicted Secondary structure

No model constructed - rank, confidence too low

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Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
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