Job Description Undefined Confidence 99.78% Date Thu Nov 13 08:26:15 GMT 2025 Rank 429 Aligned Residues 237 % Identity 12% Template c3k6kA_ PDB info PDB header: hydrolase Chain: A: PDB Molecule: Esterase/lipase PDBTitle: crystal structure at 2.2 angstrom of hsl-homolog este7 from a metagenome library PDB Entry: PDBe RCSB PDBj Resolution UNK

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		27	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.				.	.	.	.	.	.	.	70	.	.	.	.	.	.	.			.	.	80	.
Predicted Secondary structure																																						.	.	.																.	.
Query Sequence		A	P	Q	V	H	Y	R	V	E	Q	V	G	D	V	K	V	F	Y	R	E	A	G	D	P	A	A	P	A	V	L	L	L	H	G	F	A	.	.	.	A	S	S	Y	M	W	R	D	V	I	E	A	L	A	D	.	.	G	Y	H	V
Query Conservation																																						.	.	.																.	.
Alig confidence																																						.	.	.																.	.
Template Conservation
Template Sequence		A	E	G	V	E	L	T	L	T	D	L	G	G	V	P	C	I	R	Q	A	T	D	G	A	G	A	A	H	I	L	Y	F	H	G	G	G	Y	I	S	G	S	P	S	T	H	L	V	L	T	T	Q	L	A	K	Q	S	S	A	T	L
Template Known Secondary structure			T	T									T	T									T	T			S									S	T	T	T	S																		T
Template Predicted Secondary structure
		82	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.		.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Predicted Secondary structure																																						.
Query Sequence		I	A	P	D	L	P	A	F	G	Y	T	E	A	P	A	R	G	Q	Y	D	Y	T	F	A	N	L	T	K	T	I	E	R	F	T	D	Q	.	L	K	L	T	R	Y	A	M	A	V	H	D	Y	G	A	P	V	G	W	R	L	A	L
Query Conservation																																						.
Alig confidence														.	.	.	.	.	.																			.
Template Conservation														.	.	.	.	.	.
Template Sequence		W	S	L	D	Y	R	L	A	P	E	N	P	.	.	.	.	.	.	F	P	A	A	V	D	D	C	V	A	A	Y	R	A	L	L	K	T	A	G	S	A	D	R	I	I	I	A	G	D	S	A	G	G	G	L	T	T	A	S	M	L
Template Known Secondary structure						.	.	.	T	T	T	S		.	.	.	.	.	.	T	T																		S	S	G	G	G							T
Template Predicted Secondary structure														.	.	.	.	.	.
		141	.	.	.	.					.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.
Predicted Secondary structure							.	.	.	.
Query Sequence		A	H	P	S	R	.	.	.	.	I	T	A	I	I	S	Q	N	G	N	A	Y	E	E	G	L	S	A	G	W	E	P	I	R	K	Y	W	N	D	P	T	A	E	N	R	Q	A	L	S	D	F	P	T	P	A	S	I	K	W	Q	Y
Query Conservation							.	.	.	.
Alig confidence							.	.	.	.																																								.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																		.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		K	A	K	E	D	G	L	P	M	P	A	G	L	V	M	L	S	P	F	V	D	L	T	L	S	R	W	S	N	S	N	L	A	D	R	D	F	L	A	E	P	D	T	L	G	E	M	S	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure						T	T	.	.	.	.	S						S					T	T			S						T	G	G	G		S	S	S										.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																		.	.	.	.	.	.	.	.	.	.	.	.
		197	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.
Predicted Secondary structure
Query Sequence		V	E	G	V	S	D	T	S	L	V	A	P	D	A	Y	T	L	E	G	A	Q	I	L	R	P	G	M	A	D	I	Q	L	D	L	L	L	D	Y	A	T	N	V	E	Q	Y	P	A	F	Q	A	Y	F	R	E	Y	Q	P	P	L	L
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	L	Y	V	G	G	E	D	R	K	N	P	L	I	S	P	V	Y	A	D	L	S	G	L	P	E	M	L
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.					T	T	S		T	T		T	T	T		G	G	G	S			T	T	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
		257	.	.	260	.	.	.	.	.	.	.	.			.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.		.	.	.	.	.	290	.						.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.
Predicted Secondary structure														.	.																	.								.	.	.	.	.
Query Sequence		A	V	W	G	E	H	D	P	F	F	L	P	.	.	P	G	A	E	A	W	K	R	D	I	P	D	A	D	I	R	.	L	Y	D	T	G	H	F	.	.	.	.	.	A	L	E	T	H	S	E	V	I	I	P	T	I	R	Q	F	L
Query Conservation														.	.																	.								.	.	.	.	.
Alig confidence														.	.																	.								.	.	.	.	.
Template Conservation
Template Sequence		I	H	V	G	S	E	E	A	L	L	S	D	S	T	T	L	A	E	R	A	G	A	A	G	V	S	V	E	L	K	I	W	P	D	M	P	H	V	F	Q	M	Y	G	K	F	V	N	A	A	D	I	S	I	K	E	I	C	H	W	I
Template Known Secondary structure						S	S		T	T														T	T									T	T			T	T	G	G	G	G	T	T	T
Template Predicted Secondary structure
		309	310	.	.	.
Predicted Secondary structure
Query Sequence		D	D	H	V	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	A	R	I	S
Template Known Secondary structure			T	T
Template Predicted Secondary structure

No model constructed - rank, confidence too low

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Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
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