Job Description Undefined Confidence 100.00% Date Thu Nov 13 08:26:15 GMT 2025 Rank 213 Aligned Residues 270 % Identity 14% Template c2xmqA_ PDB info PDB header: signaling protein Chain: A: PDB Molecule: PROTEIN NDRG2 PDBTitle: crystal structure of human ndrg2 protein provides insight into its role as a tumor suppressor PDB Entry: PDBe RCSB PDBj Resolution UNK

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

31

.

.

.

.

.

.

.

.

40

.

.

.

.

.

.

.

.

.

50

.

.

.

.

.

.

.

.

.

60

.

.

.

.

.

.

.

.

.

70

.

.

.

.

.

.

.

.

.

80

.

.

Predicted Secondary structure

.

.

.

.

.

.

.

.

Query Sequence

H

Y

R

V

E

Q

V

G

D

V

K

V

F

Y

R

E

A

G

D

P

.

.

A

A

P

A

V

L

L

L

H

G

F

A

A

S

S

Y

M

W

.

.

.

.

.

.

R

D

V

I

E

A

L

A

D

G

Y

H

V

I

Query Conservation

.

.

.

.

.

.

.

.

Alig confidence

.

.

.

.

.

.

.

.

Template Conservation

Template Sequence

K

T

H

S

V

E

T

P

Y

G

S

V

T

F

T

V

Y

G

T

P

K

P

K

R

P

A

I

L

T

Y

H

D

V

G

L

N

Y

K

S

C

F

Q

P

L

F

Q

F

E

D

M

Q

E

I

I

Q

N

F

V

R

V

Template Known Secondary structure

T

T

S

T

T

S

.

.

T

T

T

S

T

T

S

Template Predicted Secondary structure

83

.

.

.

.

.

.

90

.

.

.

.

.

.

.

.

.

100

.

.

.

.

.

.

.

.

.

110

.

.

.

.

.

.

.

.

.

120

.

.

.

.

.

.

.

.

.

130

.

.

.

.

.

.

.

.

.

140

.

Predicted Secondary structure

.

Query Sequence

A

P

D

L

P

A

F

G

Y

T

E

A

P

A

R

G

Q

Y

D

Y

.

T

F

A

N

L

T

K

T

I

E

R

F

T

D

Q

L

K

L

T

R

Y

A

M

A

V

H

D

Y

G

A

P

V

G

W

R

L

A

L

A

Query Conservation

.

Alig confidence

.

Template Conservation

Template Sequence

H

V

D

A

P

G

M

E

E

G

A

P

V

F

P

L

G

Y

Q

Y

P

S

L

D

Q

L

A

D

M

I

P

C

V

L

Q

Y

L

N

F

S

T

I

I

G

V

G

V

G

A

G

A

Y

I

L

A

R

Y

A

L

N

Template Known Secondary structure

T

T

S

T

T

.

.

.

.

.

T

T

.

.

.

T

T

T

T

Template Predicted Secondary structure

142

.

.

.

.

.

.

.

150

.

.

.

.

.

.

.

.

.

160

.

.

.

.

.

.

.

.

.

170

.

.

.

.

.

.

.

.

.

180

.

.

.

.

.

.

.

.

.

190

.

.

.

.

.

.

.

.

.

200

.

Predicted Secondary structure

Query Sequence

H

P

S

R

I

T

A

I

I

S

Q

N

G

N

A

Y

E

E

G

L

S

A

G

W

E

P

I

R

K

Y

W

N

D

P

T

A

E

N

R

Q

A

L

S

D

F

P

T

P

A

S

I

K

W

Q

Y

V

E

G

V

S

Query Conservation

Alig confidence

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

Template Conservation

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

Template Sequence

H

P

D

T

V

E

G

L

V

L

I

N

I

D

P

N

A

K

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

G

W

M

D

W

A

A

H

K

L

T

G

L

T

S

S

I

P

E

M

I

L

G

H

L

F

S

Template Known Secondary structure

G

G

G

S

S

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

T

T

S

S

Template Predicted Secondary structure

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

202

.

.

.

.

.

.

.

210

.

.

.

.

.

.

.

.

.

220

.

.

.

.

.

.

.

.

.

230

.

.

.

.

.

.

.

.

.

240

.

.

.

.

.

.

.

.

.

250

.

.

.

.

.

.

.

.

.

260

.

Predicted Secondary structure

Query Sequence

D

T

S

L

V

A

P

D

A

Y

T

L

E

G

A

Q

I

L

R

P

G

M

A

D

I

Q

L

D

L

L

L

D

Y

A

T

N

V

E

Q

Y

P

A

F

Q

A

Y

F

R

E

Y

Q

P

P

L

L

A

V

W

G

E

Query Conservation

Alig confidence

Template Conservation

Template Sequence

Q

E

E

L

S

G

N

S

E

L

I

Q

K

Y

R

N

I

I

T

H

A

P

N

L

D

N

I

E

N

Y

W

N

S

Y

N

N

R

R

D

L

N

F

E

R

G

G

D

I

T

L

R

C

P

V

M

L

V

V

G

D

Template Known Secondary structure

T

T

T

T

T

.

.

.

T

T

S

S

S

S

S

T

Template Predicted Secondary structure

262

.

.

.

.

.

.

.

270

.

.

.

.

.

.

.

.

.

280

.

.

.

.

.

.

.

.

.

290

.

.

.

.

.

.

.

.

.

300

.

.

.

.

.

.

.

.

.

310

.

.

.

.

.

Predicted Secondary structure

.

Query Sequence

H

D

P

F

F

L

P

P

G

A

E

A

W

K

R

D

I

P

D

A

D

I

R

.

L

Y

D

T

G

H

F

A

L

E

T

H

S

E

V

I

I

P

T

I

R

Q

F

L

D

D

H

V

S

L

H

Query Conservation

.

Alig confidence

.

Template Conservation

Template Sequence

Q

A

P

H

E

D

A

V

V

E

C

N

S

K

L

D

P

T

Q

T

S

F

L

K

M

A

D

S

G

G

Q

P

Q

L

T

Q

P

G

K

L

T

E

A

F

K

Y

F

L

Q

G

M

G

Y

M

A

Template Known Secondary structure

T

T

T

S

T

T

S

T

T

T

T

T

T

Template Predicted Secondary structure

No model constructed - rank, confidence too low

---

Phyre is now FREE for commercial users!

All images and data generated by Phyre2 are free to use in any publication with acknowledgement

Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
© Structural Bioinformatics Group, Imperial College, London Michael Sternberg   Disclaimer Terms and Conditions		Phyre2 is part of Genome3D