Job Description Undefined Confidence 99.94% Date Thu Nov 13 08:26:15 GMT 2025 Rank 446 Aligned Residues 250 % Identity 11% Template c2wfmA_ PDB info PDB header: hydrolase Chain: A: PDB Molecule: POLYNEURIDINE ALDEHYDE ESTERASE PDBTitle: crystal structure of polyneuridine aldehyde esterase mutant (h244a) PDB Entry: PDBe RCSB PDBj Resolution UNK

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

51

.

.

.

.

.

.

.

.

60

.

.

.

.

.

.

.

.

.

70

.

.

.

.

.

.

.

.

.

80

.

.

.

.

.

.

.

.

.

90

.

.

.

.

.

.

.

.

.

100

.

.

.

.

.

.

.

.

.

Predicted Secondary structure

.

Query Sequence

A

A

P

A

V

L

L

L

H

G

F

A

A

S

S

Y

M

W

R

D

V

I

E

A

L

.

A

D

G

Y

H

V

I

A

P

D

L

P

A

F

G

Y

T

E

A

P

A

R

G

Q

Y

D

Y

T

F

A

N

L

T

K

Query Conservation

.

Alig confidence

.

.

.

Template Conservation

.

.

Template Sequence

Q

Q

K

H

F

V

L

V

H

G

G

C

L

G

A

W

I

W

Y

K

L

K

P

L

L

E

S

A

G

H

K

V

T

A

V

D

L

S

A

A

G

I

N

P

R

R

L

D

.

.

E

I

H

T

F

R

D

Y

S

E

Template Known Secondary structure

T

T

G

G

G

G

T

T

T

T

.

.

T

T

S

T

T

S

G

G

.

.

G

S

Template Predicted Secondary structure

.

.

110

.

.

.

.

.

.

.

.

.

120

.

.

.

.

.

.

.

.

.

130

.

.

.

.

.

.

.

.

.

140

.

.

.

.

.

.

.

.

.

150

.

.

.

.

.

.

.

.

.

160

.

.

.

.

.

.

.

.

Predicted Secondary structure

.

Query Sequence

T

I

E

R

F

T

D

Q

L

K

L

.

T

R

Y

A

M

A

V

H

D

Y

G

A

P

V

G

W

R

L

A

L

A

H

P

S

R

I

T

A

I

I

S

Q

N

G

N

A

Y

E

E

G

L

S

A

G

W

E

P

I

Query Conservation

.

Alig confidence

.

Template Conservation

Template Sequence

P

L

M

E

V

M

A

S

I

P

P

D

E

K

V

V

L

L

G

H

S

F

G

G

M

S

L

G

L

A

M

E

T

Y

P

E

K

I

S

V

A

V

F

M

S

A

M

M

P

D

P

N

H

S

L

T

Y

P

F

E

Template Known Secondary structure

T

S

T

T

T

G

G

G

T

T

S

T

T

Template Predicted Secondary structure

169

170

.

.

.

.

.

.

.

.

.

180

.

.

.

.

.

.

.

.

.

190

.

.

.

.

.

.

.

.

.

200

.

.

.

.

.

.

.

.

.

210

.

.

.

.

.

.

.

.

.

220

.

.

.

.

.

.

.

.

Predicted Secondary structure

Query Sequence

R

K

Y

W

N

D

P

T

A

E

N

R

Q

A

L

S

D

F

P

T

P

A

S

I

K

W

Q

Y

V

E

G

V

S

D

T

S

L

V

A

P

D

A

Y

T

L

E

G

A

Q

I

L

R

P

G

M

A

D

I

Q

L

Query Conservation

Alig confidence

.

.

.

.

.

.

.

Template Conservation

.

.

.

.

.

.

.

Template Sequence

K

Y

N

E

K

C

P

A

D

M

M

L

D

S

Q

F

S

T

Y

G

N

P

E

.

.

.

.

.

.

.

N

P

G

M

S

M

I

L

G

P

Q

F

M

A

L

K

M

F

Q

N

C

S

V

E

D

L

E

L

A

K

Template Known Secondary structure

S

T

T

T

T

T

T

S

T

T

.

.

.

.

.

.

.

S

S

T

T

S

Template Predicted Secondary structure

.

.

.

.

.

.

.

229

230

.

.

.

.

.

.

.

.

.

240

.

.

.

.

.

.

.

.

.

250

.

.

.

.

.

.

.

.

.

260

.

.

.

.

.

.

.

.

.

270

.

.

.

.

.

.

.

.

.

280

.

.

.

.

.

.

Predicted Secondary structure

.

.

Query Sequence

D

L

L

L

D

Y

A

T

N

V

.

.

E

Q

Y

P

A

F

Q

A

Y

F

R

E

Y

Q

P

P

L

L

A

V

W

G

E

H

D

P

F

F

L

P

P

G

A

E

A

W

K

R

D

I

P

D

A

D

I

R

L

Y

Query Conservation

.

.

Alig confidence

.

.

Template Conservation

Template Sequence

M

L

T

R

P

G

S

L

F

F

Q

D

L

A

K

A

K

K

F

S

T

E

R

Y

G

S

V

K

R

A

Y

I

F

C

N

E

D

K

S

F

P

V

E

F

Q

K

W

F

V

E

S

V

G

A

D

K

V

K

E

I

Template Known Secondary structure

B

T

T

S

.

.

.

T

T

T

G

G

G

S

T

T

S

S

S

T

S

Template Predicted Secondary structure

287

.

.

290

.

.

.

.

.

.

.

.

.

300

.

.

.

.

.

.

.

.

.

Predicted Secondary structure

.

Query Sequence

D

.

T

G

H

F

A

L

E

T

H

S

E

V

I

I

P

T

I

R

Q

F

L

D

Query Conservation

.

Alig confidence

.

Template Conservation

Template Sequence

K

E

A

D

A

M

G

M

L

S

Q

P

R

E

V

C

K

C

L

L

D

I

S

D

Template Known Secondary structure

T

T

S

S

Template Predicted Secondary structure

No model constructed - rank, confidence too low

---

Phyre is now FREE for commercial users!

All images and data generated by Phyre2 are free to use in any publication with acknowledgement

Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
© Structural Bioinformatics Group, Imperial College, London Michael Sternberg   Disclaimer Terms and Conditions		Phyre2 is part of Genome3D