Job Description Undefined Confidence 99.92% Date Thu Nov 13 08:26:15 GMT 2025 Rank 273 Aligned Residues 270 % Identity 13% Template c2rauA_ PDB info PDB header: hydrolase Chain: A: PDB Molecule: Putative esterase PDBTitle: crystal structure of a putative lipase (np_343859.1) from sulfolobus solfataricus at 1.85 a resolution PDB Entry: PDBe RCSB PDBj Resolution UNK

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		38	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.																	.	.	70	.	.	.	.	.	.		.	.	.	80
Predicted Secondary structure																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.										.
Query Sequence		G	D	V	K	V	F	Y	R	E	A	G	D	P	A	A	P	A	V	L	L	L	H	G	F	A	A	S	S	Y	M	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	W	R	D	V	I	E	A	L	A	.	D	G	Y	H
Query Conservation																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.										.
Alig confidence																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.										.
Template Conservation
Template Sequence		D	I	I	S	L	H	K	V	N	L	I	G	G	G	N	D	A	V	L	I	L	P	G	T	W	S	S	G	E	Q	L	V	T	I	S	W	N	G	V	H	Y	T	I	P	D	Y	R	K	S	I	V	L	Y	L	A	R	N	G	F	N
Template Known Secondary structure												T	T												T	T									S			T	T				S				G	G	G									T	T
Template Predicted Secondary structure
		81	.	.		.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100						.	.	.	.	.	.	.	.	.	110	.	.	.	.	.		.	.	.					.	120	.		.	.	.	.	.	.	.
Predicted Secondary structure					.																		.	.	.	.	.																.				.	.	.	.				.
Query Sequence		V	I	A	.	P	D	L	P	A	F	G	Y	T	E	A	P	A	R	G	Q	Y	.	.	.	.	.	D	Y	T	F	A	N	L	T	K	T	I	E	R	F	T	.	D	Q	L	.	.	.	.	K	L	T	.	R	Y	A	M	A	V	H
Query Conservation					.																		.	.	.	.	.																.				.	.	.	.				.
Alig confidence					.																		.	.	.	.	.																.				.	.	.	.				.
Template Conservation
Template Sequence		V	Y	T	T	I	D	Y	R	T	H	Y	V	P	P	F	L	K	D	R	Q	L	S	F	T	A	N	N	W	G	W	S	T	W	I	S	D	I	K	E	V	V	S	S	F	I	K	R	D	S	G	Q	E	R	R	I	Y	L	A	G	E
Template Known Secondary structure					.				G	G	G	G			T	T			G	G	G	G	G	G	G	T	T	.		S														.									S	S	.
Template Predicted Secondary structure
		129	130	.	.	.	.	.	.	.	.	.	140	.	.		.	.	.	.	.	.	.		150	.	.	.	.	.	.	.	.	.	160	.	.												.	.	.	.	.	.	.	170	.	.	.	.	.
Predicted Secondary structure																.								.														.	.	.	.	.	.	.	.	.	.	.
Query Sequence		D	Y	G	A	P	V	G	W	R	L	A	L	A	H	.	P	S	R	I	T	A	I	.	I	S	Q	N	G	N	A	Y	E	E	G	L	S	.	.	.	.	.	.	.	.	.	.	.	A	G	W	E	P	I	R	K	Y	W	N	D	P
Query Conservation																.								.														.	.	.	.	.	.	.	.	.	.	.
Alig confidence																.								.														.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		S	F	G	G	I	A	A	L	N	Y	S	S	L	Y	W	K	N	D	I	K	G	L	L	I	L	L	D	G	G	P	T	K	H	G	I	R	F	Y	T	P	E	V	N	S	I	E	E	E	A	K	G	I	Y	V	I	P	S	R	G	G
Template Known Secondary structure		T																						.				S		S	.	B	.	T	T			S	S			S		S	S	S			S	S	S								S	S	S
Template Predicted Secondary structure
		176	.	.			.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.
Predicted Secondary structure					.	.
Query Sequence		T	A	E	.	.	N	R	Q	A	L	S	D	F	P	T	P	A	S	I	K	W	Q	Y	V	E	G	V	S	D	T	S	L	V	A	P	D	A	Y	T	L	E	G	A	Q	I	L	R	P	G	M	A	D	I	Q	L	D	L	L	L	D
Query Conservation					.	.
Alig confidence					.	.
Template Conservation
Template Sequence		P	N	N	P	I	W	S	Y	A	L	A	N	P	D	P	S	P	D	P	K	Y	K	S	I	S	D	F	L	D	S	S	L	Y	V	T	G	S	A	N	P	Y	D	Y	P	Y	S	K	K	E	D	F	P	I	L	A	S	F	D	P	Y
Template Known Secondary structure		T	T		T								S		S	S		S	S	T	T	S	S	S					S			.				T	T	S			T	T	S	T	T				T	T	S	S					T	S		S
Template Predicted Secondary structure
		234	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.		260	.		.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.		.	.	.	.	.	.	.	290
Predicted Secondary structure																												.			.																						.
Query Sequence		Y	A	T	N	V	E	Q	Y	P	A	F	Q	A	Y	F	R	E	Y	Q	P	P	L	L	A	V	W	.	G	E	.	H	D	P	F	F	L	P	P	G	A	E	A	W	K	R	D	I	P	D	A	D	.	I	R	L	Y	D	T	G	H
Query Conservation																												.			.																						.
Alig confidence																												.			.				.	.											.	.					.
Template Conservation																																			.	.											.	.
Template Sequence		W	P	Y	R	L	S	L	E	R	D	L	K	F	D	Y	E	G	I	L	V	P	T	I	A	F	V	V	S	E	R	F	G	I	.	.	Q	I	F	D	S	K	I	L	P	S	.	.	N	S	E	I	I	I	L	L	K	G	Y	G	H
Template Known Secondary structure									T	T	T						T	T										.		T	T	T			.	.			B		G	G	G	S		T	.	.	T					.			T	T			G
Template Predicted Secondary structure																																			.	.											.	.
		291		.	.	.			.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.
Predicted Secondary structure			.				.	.
Query Sequence		F	.	A	L	E	.	.	T	H	S	E	V	I	I	P	T	I	R	Q	F	L	D	D	H
Query Conservation			.				.	.
Alig confidence			.				.	.
Template Conservation
Template Sequence		L	D	V	Y	T	G	E	N	S	E	K	D	V	N	S	V	V	L	K	W	L	S	Q	Q
Template Known Secondary structure		G	G	G	T	S	S	T	T
Template Predicted Secondary structure

No model constructed - rank, confidence too low

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Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
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