Job Description Undefined Confidence 99.97% Date Thu Nov 13 08:26:15 GMT 2025 Rank 167 Aligned Residues 252 % Identity 16% Template c2oclA_ PDB info PDB header: hydrolase Chain: A: PDB Molecule: Valacyclovir hydrolase PDBTitle: crystal structure of valacyclovir hydrolase s122a mutant PDB Entry: PDBe RCSB PDBj Resolution UNK

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		29	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.		.	.	80	.	.	.	.	.	.	.
Predicted Secondary structure																																																			.
Query Sequence		Q	V	H	Y	R	V	E	Q	V	G	D	V	K	V	F	Y	R	E	A	G	D	P	A	A	P	A	V	L	L	L	H	G	F	A	A	S	S	Y	M	W	R	D	V	I	E	A	L	A	D	.	G	Y	H	V	I	A	P	D	L	P
Query Conservation																																																			.
Alig confidence																																																			.
Template Conservation
Template Sequence		S	V	T	S	A	K	V	A	V	N	G	V	Q	L	H	Y	Q	Q	T	G	E	G	D	H	A	V	L	L	L	P	G	M	L	G	S	G	E	T	D	F	G	P	Q	L	K	N	L	N	K	K	L	F	T	V	V	A	W	D	P	R
Template Known Secondary structure											T	T												S									T	T														S		T	T	T									T
Template Predicted Secondary structure
		88	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.
Predicted Secondary structure
Query Sequence		A	F	G	Y	T	E	A	P	A	R	G	Q	Y	D	Y	T	F	A	N	L	T	K	T	I	E	R	F	T	D	Q	L	K	L	T	R	Y	A	M	A	V	H	D	Y	G	A	P	V	G	W	R	L	A	L	A	H	P	S	R	I	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	Y	G	H	S	R	P	P	D	R	D	F	P	A	D	F	F	E	R	D	A	K	D	A	V	D	L	M	K	A	L	K	F	K	K	V	S	L	L	G	W	A	D	G	G	I	T	A	L	I	A	A	A	K	Y	P	S	Y	I	H
Template Known Secondary structure		T	S	T	T			S	S						T	T																T	T		S	S							T													S	T	T	T
Template Predicted Secondary structure
		148	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.
Predicted Secondary structure
Query Sequence		A	I	I	S	Q	N	G	N	A	Y	E	E	G	L	S	A	G	W	E	P	I	R	K	Y	W	N	D	P	T	A	E	N	R	Q	A	L	S	D	F	P	T	P	A	S	I	K	W	Q	Y	V	E	G	V	S	D	T	S	L	V	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	M	V	I	W	G	A	N	A	Y	V	T	D	E	D	S	M	I	Y	E	G	I	R	D	V	S	K	W	S	E	R	T	R	K	P	L	E	A	L	Y	G	Y	D	Y	F	A	R	T	C	E	K	W	V	D	G	I	R	Q	F	K
Template Known Secondary structure							S			S	B											T	T	S		G	G	G	S																														G	G	G
Template Predicted Secondary structure
		208	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.
Predicted Secondary structure
Query Sequence		P	D	A	Y	T	L	E	G	A	Q	I	L	R	P	G	M	A	D	I	Q	L	D	L	L	L	D	Y	A	T	N	V	E	Q	Y	P	A	F	Q	A	Y	F	R	E	Y	Q	P	P	L	L	A	V	W	G	E	H	D	P	F	F	L
Query Conservation
Alig confidence													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		H	L	P	D	G	N	I	C	R	H	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	L	P	R	V	Q	C	P	A	L	I	V	H	G	E	K	D	P	L	V	P
Template Known Secondary structure		G	S	G	G	G	B	S	S	G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	G	G			S								T	T		S	S	S
Template Predicted Secondary structure													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
		268	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.		.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																		.
Query Sequence		P	P	G	A	E	A	W	K	R	D	I	P	D	A	D	I	.	R	L	Y	D	T	G	H	F	A	L	E	T	H	S	E	V	I	I	P	T	I	R	Q	F	L	D
Query Conservation																		.
Alig confidence																		.
Template Conservation
Template Sequence		R	F	H	A	D	F	I	H	K	H	V	K	G	S	R	L	H	L	M	P	E	G	K	H	N	L	H	L	R	F	A	D	E	F	N	K	L	A	E	D	F	L	Q
Template Known Secondary structure												S	T	T							T	T			T	T					T
Template Predicted Secondary structure

No model constructed - rank, confidence too low

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Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
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