Job Description Undefined Confidence 99.93% Date Thu Nov 13 08:26:15 GMT 2025 Rank 169 Aligned Residues 286 % Identity 14% Template c1hlgA_ PDB info PDB header: hydrolase Chain: A: PDB Molecule: LIPASE, GASTRIC PDBTitle: crystal structure of human gastric lipase PDB Entry: PDBe RCSB PDBj Resolution UNK

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		28	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.						.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.							.	70	.	.	.	.	.	.
Predicted Secondary structure																						.	.	.	.	.																						.	.	.	.	.	.
Query Sequence		P	Q	V	H	Y	R	V	E	Q	V	G	D	V	K	V	F	Y	R	E	A	.	.	.	.	.	G	D	P	A	A	P	A	V	L	L	L	H	G	F	A	A	S	S	Y	M	W	.	.	.	.	.	.	R	D	V	I	E	A	L	A
Query Conservation																						.	.	.	.	.																						.	.	.	.	.	.
Alig confidence																						.	.	.	.	.																						.	.	.	.	.	.
Template Conservation
Template Sequence		P	N	E	E	Y	E	V	V	T	E	D	G	Y	I	L	E	V	N	R	I	P	Y	G	K	K	N	S	G	Q	R	P	V	V	F	L	Q	H	G	L	L	A	S	A	T	N	W	I	S	N	L	P	N	N	S	L	A	F	I	L	A
Template Known Secondary structure											T	T	S	B									S		S	S	T	T	S	S	.	.								T	T			G	G	G	G	G	S	S		T	T	S
Template Predicted Secondary structure
		77		.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.							.	.	.	.	.	100	.	.	.	.	.	.	.	.						.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.
Predicted Secondary structure			.																		.	.	.	.	.	.															.	.	.	.	.
Query Sequence		D	.	G	Y	H	V	I	A	P	D	L	P	A	F	G	Y	T	E	A	.	.	.	.	.	.	P	A	R	G	Q	Y	D	Y	T	F	A	N	L	T	.	.	.	.	.	K	T	I	E	R	F	T	D	Q	L	K	L	T	R	Y	A
Query Conservation			.																		.	.	.	.	.	.															.	.	.	.	.
Alig confidence			.																		.	.	.	.	.	.															.	.	.	.	.
Template Conservation
Template Sequence		D	A	G	Y	D	V	W	L	G	N	S	R	G	N	T	W	A	R	R	N	L	Y	Y	S	P	D	S	V	E	F	W	A	F	S	F	D	E	M	A	K	Y	D	L	P	A	T	I	D	F	I	V	K	K	T	G	Q	K	Q	L	H
Template Known Secondary structure			T	T									T	T	S	T	T				B	S	S	S		T	T	S	T	G	G	G																										S
Template Predicted Secondary structure
		125	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.				.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.
Predicted Secondary structure																						.	.	.
Query Sequence		M	A	V	H	D	Y	G	A	P	V	G	W	R	L	A	L	A	H	P	S	.	.	.	R	I	T	A	I	I	S	Q	N	G	N	A	Y	E	E	G	L	S	A	G	W	E	P	I	R	K	Y	W	N	D	P	T	A	E	N	R	Q
Query Conservation																						.	.	.
Alig confidence																						.	.	.
Template Conservation
Template Sequence		Y	V	G	H	S	Q	G	T	T	I	G	F	I	A	F	S	T	N	P	S	L	A	K	R	I	K	T	F	Y	A	L	A	P	V	A	T	V	K	Y	T	K	S	L	I	N	K	L	R	F	V	P	Q	S	L	F	K	F	I	F	G
Template Known Secondary structure						T																		T	T								S			S			S	S			S	G	G	G	G	G	G	G
Template Predicted Secondary structure
		182	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.																			.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.
Predicted Secondary structure																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		A	L	S	D	F	P	T	P	A	S	I	K	W	Q	Y	V	E	G	V	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	T	S	L	V	A	P	D	A	Y	T	L	E	G	A	Q	I	L	R	P	G	M
Query Conservation																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		D	K	I	F	Y	P	H	N	F	F	D	Q	F	L	A	T	E	V	C	S	R	E	M	L	N	L	L	C	S	N	A	L	F	I	I	C	G	F	D	S	K	N	F	N	T	S	R	L	D	V	Y	L	S	H	N	P	A	G	T	S
Template Known Secondary structure		S	S	B				T	T	T	T	T	T	S										S						T												T	T	S		G	G	G						T	T			S			B
Template Predicted Secondary structure
		224	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.																	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.
Predicted Secondary structure																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		A	D	I	Q	L	D	L	L	L	D	Y	A	T	N	V	E	Q	Y	P	A	F	Q	A	Y	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	F	R	E	Y	Q	P	P	L	L	A	V	W	G	E	H	D	P	F	F	L
Query Conservation																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		V	Q	N	M	F	H	W	T	Q	A	V	K	S	G	K	F	Q	A	Y	D	W	G	S	P	V	Q	N	R	M	H	Y	D	Q	S	Q	P	P	Y	Y	N	V	T	A	M	N	V	P	I	A	V	W	N	G	G	K	D	L	L	A	D
Template Known Secondary structure																S		B					S	S									S	S	S	S	.	.	B			G	G	G			S								T	T		S	S	S
Template Predicted Secondary structure
		268	.	270	.	.	.	.	.	.	.	.	.	280			.	.	.	.	.	.	.	.	.	290	.	.	.	.				.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.
Predicted Secondary structure															.	.															.	.	.
Query Sequence		P	P	G	A	E	A	W	K	R	D	I	P	D	.	.	A	D	I	R	L	Y	D	T	G	H	F	A	L	E	.	.	.	T	H	S	E	V	I	I	P	T	I	R	Q	F	L	D	D	H	V	S
Query Conservation															.	.															.	.	.
Alig confidence															.	.															.	.	.
Template Conservation
Template Sequence		P	Q	D	V	G	L	L	L	P	K	L	P	N	L	I	Y	H	K	E	I	P	F	Y	N	H	L	D	F	I	W	A	M	D	A	P	Q	E	V	Y	N	D	I	V	S	M	I	S	E	D	K	K
Template Known Secondary structure													T	T								T	T			T	T						T	T														T	T	T	T
Template Predicted Secondary structure

No model constructed - rank, confidence too low

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Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
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