Job Description Q19726 Confidence 100.00% Date Sat Apr 13 13:19:58 BST 2013 Rank 8 Aligned Residues 363 % Identity 31% Template c4fl2A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch Resolution 2.19 Å Model Dimensions (Å) X:85.687 Y:70.084 Z:49.311

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		25	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.					.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.		.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																							.	.	.	.																																					.
Query SS confidence																							.	.	.	.																																					.
Query Sequence		K	Q	N	N	E	W	F	H	G	V	L	Q	R	Q	D	A	D	E	L	L	V	.	.	.	.	K	P	G	S	F	L	L	R	A	S	E	V	H	G	K	M	S	M	I	L	S	V	R	H	D	G	K	L	H	N	I	A	V	N	S	D	.	T	G	E	N	F	W	F	E	G	H	R	E	K	S	I	D	Q	L
Query Conservation																							.	.	.	.																																					.
Alig confidence																							.	.	.	.												.	.																								.
Template Conservation																																						.	.
Template Sequence		H	E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	D	.	.	N	N	G	S	Y	A	L	C	L	L	H	E	G	K	V	L	H	Y	R	I	D	K	D	K	T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L
Template Known Secondary structure		G	G	G	S	T	T	B			S												S	S	S			T	T									.	.	T	T	T									T	T											T	T	S				S	T	T				B	S	S
Template Predicted Secondary structure																																						.	.
Template SS confidence
		163	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.			.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
		100	.	.	.	.	.	.	.	.	.	110	.	.	.	.																	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.									140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.
Predicted Secondary structure																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																										.	.	.	.	.	.	.	.
Query SS confidence																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																										.	.	.	.	.	.	.	.
Query Sequence		V	Q	W	H	M	T	T	S	T	P	I	T	K	T	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	V	K	L	K	Y	P	I	G	K	A	D	W	I	I	S	H	E	N	V	I	F	I	K	K	.	.	.	.	.	.	.	.	L	G	E	G	A	F	G	E	V	S	L	A	E	C	E	I
Query Conservation																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																										.	.	.	.	.	.	.	.
Alig confidence																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																										.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		V	E	H	Y	S	Y	K	A	D	G	L	L	R	V	L	T	V	P	C	Q	K	I	G	T	Q	R	E	A	L	P	M	D	T	E	V	Y	E	S	P	Y	A	D	P	E	E	I	R	P	K	E	V	Y	L	D	R	K	L	L	T	L	E	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M
Template Known Secondary structure						T	T	B		T	T	S	S	S				S	B				S				T	T			G	G	G	S	G	G	G	S		G	G	G	S	T	T	S				S	S	S	B			G	G	G												T	T
Template Predicted Secondary structure
Template SS confidence
		241	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320
		156	.	.	.	160	.	.	.	.	.	.	.	.	.	170		.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.
Predicted Secondary structure																	.
Query SS confidence																	.
Query Sequence		G	G	R	K	V	E	T	A	V	K	T	M	R	C	Q	.	M	T	R	D	T	R	A	A	F	M	K	E	A	R	L	M	R	K	Y	S	H	P	H	I	V	R	I	I	G	K	I	I	V	K	H	L	P	K	V	G	L	A	V	D	A	H	P	L	M	I	V	M	E	M	C	P	H	G	S	L	L	S	F	L
Query Conservation																	.
Alig confidence																	.																																				.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																					.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	E	A	E	S	.	.	.	.	.	.	.	.	.	.	.	.	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L
Template Known Secondary structure		T	T												S	G	G	G		G	G	G																	T	T	B									S	S	S	.	.	.	.	.	.	.	.	.	.	.	.									T	T		B
Template Predicted Secondary structure																																																					.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		393	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.													.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460
		235	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.				.	.	300	.	.	.	.	.	.	.	.	.	310	.
Predicted Secondary structure																																																																	.	.	.
Query SS confidence																																																																	.	.	.
Query Sequence		R	K	N	K	G	K	T	T	L	S	E	R	L	R	F	C	I	E	S	A	D	G	L	A	Y	L	E	K	K	Q	C	L	H	R	D	I	A	A	R	N	C	L	L	S	I	T	D	Q	I	K	I	S	D	F	G	L	S	D	D	K	R	T	E	.	.	.	M	H	D	D	T	L	D	K	V	P	V	K	W	L
Query Conservation																																																																	.	.	.
Alig confidence				.																																																													.	.	.
Template Conservation				.
Template Sequence		Q	Q	.	N	R	H	V	K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y
Template Known Secondary structure				.		T	T	S																						T	T				S			S	G	G	G						T	T							T	T					T	T								S		B	T	T	B		G	G	G	G
Template Predicted Secondary structure				.
Template SS confidence
		461	.		.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.
		312	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	P	E	V	M	Q	D	K	L	Y	S	L	K	S	D	V	W	A	F	G	V	L	M	W	E	I	Y	A	D	G	A	D	P	Y	P	G	M	T	N	L	V	T	R	A	K	I	F	C	D	D	Y	R	M	T	F	P	E	T	T	P	P	T	I	S	E	I	A	L	K	Q	C	W	A	K	L	P	S	D	R	A
Query Conservation
Alig confidence																																																.																				.
Template Conservation																																																.																				.
Template Sequence		A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E	V	T	A	M	L	.	E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	.	M	N	L	C	W	T	Y	D	V	E	N	R	P
Template Known Secondary structure																													T	T	T			S	S	T	T											.		T	T							T	T									.					T		S	S	T	T	T	S
Template Predicted Secondary structure																																																.																				.
Template SS confidence
		540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.		.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.		.	.	.	.	.	610	.	.	.	.	.	.	.
		392	.	.	.	.	.	.	.	400	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	M	K	T	V	H	H	K	L	K	D	L	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	F	A	A	V	E	L	R	L	R	N	Y	Y
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		618	.	620	.	.	.	.	.	.	.	.	.	630

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D