Job Description Q19726 Confidence 100.00% Date Sat Apr 13 13:19:58 BST 2013 Rank 87 Aligned Residues 265 % Identity 30% Template c4e1zA_ PDB info PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structure of mouse tyk-2 complexed to a 3-aminoindazole inhibitor Resolution 2.50 Å

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		128	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.			.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.
Predicted Secondary structure																													.	.
Query SS confidence																													.	.
Query Sequence		I	I	S	H	E	N	V	I	F	I	K	K	L	G	E	G	A	F	G	E	V	S	L	A	E	C	E	.	.	I	G	G	R	K	V	E	T	A	V	K	T	M	R	C	Q	M	T	R	D	T	R	A	A	F	M	K	E	A	R	L	M	R	K	Y	S	H	P	H	I	V	R	I	I	G	K	I	I	V	K	H
Query Conservation																													.	.
Alig confidence																													.	.
Template Conservation
Template Sequence		V	F	H	K	R	Y	L	K	K	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	E	G	C	G	P	Q	L	R	S	G	W	Q	R	E	I	E	I	L	R	T	L	Y	H	E	H	I	V	K	Y	K	G	C	C	E	D	K	S
Template Known Secondary structure		B			G	G	G											S	S										T	T			S	S											T	T																						T	T	B
Template Predicted Secondary structure
Template SS confidence
		887	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.
		206	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	P	K	V	G	L	A	V	D	A	H	P	L	M	I	V	M	E	M	C	P	H	G	S	L	L	S	F	L	R	K	N	K	G	K	T	T	L	S	E	R	L	R	F	C	I	E	S	A	D	G	L	A	Y	L	E	K	K	Q	C	L	H	R	D	I	A	A	R	N	C	L	L	S	I	T	D	Q	I	K	I
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.																				.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.																				.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	V	Q	L	V	M	E	Y	V	P	L	G	S	L	R	D	Y	L	P	R	.	.	H	C	V	G	L	A	Q	L	L	L	F	A	Q	Q	I	C	E	G	M	A	Y	L	H	A	Q	H	Y	I	H	R	A	L	A	A	R	N	V	L	L	D	N	D	R	L	V	K	I
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.									T	T							G	G	G	.	.	S																								T	T				S			S	G	G	G					G	G	G
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.																				.	.
Template SS confidence
														970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.			.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.
		286	.	.	.	290	.	.				.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.															.
Predicted Secondary structure									.	.	.																																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence									.	.	.																																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		S	D	F	G	L	S	D	.	.	.	D	K	R	T	E	M	H	D	D	T	L	D	K	V	P	V	K	W	L	A	P	E	V	M	Q	D	K	L	Y	S	L	K	S	D	V	W	A	F	G	V	L	M	W	E	I	Y	A	D	G	A	D	P	Y	P	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	M
Query Conservation									.	.	.																																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence									.	.	.																																																.								.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																											.
Template Sequence		G	D	F	G	L	A	K	A	V	P	E	G	H	E	Y	Y	R	V	R	E	D	G	D	S	P	V	F	W	Y	A	P	E	C	L	K	E	C	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	T	.	Y	C	D	S	N	Q	S	P	H	T	K	F	T	E	L	I	G	H	T	Q	G	Q
Template Known Secondary structure					T	T						T	T		S								S	S	S		G	G	G								S																					T	.	T	T		T	T	S	S											S
Template Predicted Secondary structure																																																											.
Template SS confidence
		1036	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.		.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.
		349	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	N	L	V	T	R	A	K	I	F	C	D	D	Y	R	M	T	F	P	E	T	T	P	P	T	I	S	E	I	A	L	K	Q	C	W	A	K	L	P	S	D	R	A	T	M	K	T	V	H	H	K	L	K	D	L	S	M	P	M	S
Query Conservation
Alig confidence																															.
Template Conservation																															.
Template Sequence		M	T	V	L	R	L	T	E	L	L	E	R	G	E	R	L	P	R	P	D	R	C	P	C	E	I	Y	H	L	.	M	K	N	C	W	E	T	E	A	S	F	R	P	T	F	Q	N	L	V	P	I	L	Q	T	A	Q	E	K	Y	Q
Template Known Secondary structure														T							T	T									.					T		S	S	G	G	G	S
Template Predicted Secondary structure																															.
Template SS confidence
		1115	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.		.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D