Job Description Q19726 Confidence 100.00% Date Sat Apr 13 13:19:58 BST 2013 Rank 83 Aligned Residues 241 % Identity 26% Template c3vw6B_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor Resolution 2.40 Å

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		126	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	W	I	I	S	H	E	N	V	I	F	I	K	K	L	G	E	G	A	F	G	E	V	S	L	A	E	C	E	I	G	G	R	K	V	E	T	A	V	K	T	M	R	C	Q	M	T	R	D	T	R	A	A	F	M	K	E	A	R	L	M	R	K	Y	S	H	P	H	I	V	R	I	I	G	K	I	I	V	K	H
Query Conservation
Alig confidence																																			.	.											.	.	.	.	.	.	.
Template Conservation																																			.	.											.	.	.	.	.	.	.
Template Sequence		E	Y	D	Y	E	Y	D	E	N	G	D	R	V	V	L	G	K	G	T	Y	G	I	V	Y	A	G	R	D	L	S	N	Q	V	.	.	R	I	A	I	K	E	I	P	E	Q	.	.	.	.	.	.	.	P	L	H	E	E	I	A	L	H	K	H	L	K	H	K	N	I	V	Q	Y	L	G	S	F	S	E	N	G
Template Known Secondary structure							B		T	T	S	S	B							S	S	S								T	T	T			.	.											.	.	.	.	.	.	.										T	T				T	T	B										T	T
Template Predicted Secondary structure																																			.	.											.	.	.	.	.	.	.
Template SS confidence
		672	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.			.	.	.	.	.	710	.	.	.	.								.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.
		206	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.			.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.		.	.	280	.	.
Predicted Secondary structure																																						.	.																																					.
Query SS confidence																																						.	.																																					.
Query Sequence		L	P	K	V	G	L	A	V	D	A	H	P	L	M	I	V	M	E	M	C	P	H	G	S	L	L	S	F	L	R	K	N	K	G	K	T	.	.	T	L	S	E	R	L	R	F	C	I	E	S	A	D	G	L	A	Y	L	E	K	K	Q	C	L	H	R	D	I	A	A	R	N	C	L	L	.	S	I	T	D	Q
Query Conservation																																						.	.																																					.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.																										.	.																																					.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	F	I	K	I	F	M	E	Q	V	P	G	G	S	L	S	A	L	L	R	S	K	W	G	P	L	K	D	N	E	Q	T	I	G	F	Y	T	K	Q	I	L	E	G	L	K	Y	L	H	D	N	Q	I	V	H	R	D	I	K	G	D	N	V	L	I	N	T	Y	S	G	V
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.										T	T		B								T	T				T	T																						T	T				S			S	G	G	G					T	T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
													749	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.
		283	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320			.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350		.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																								.	.																															.
Query SS confidence																																								.	.																															.
Query Sequence		I	K	I	S	D	F	G	L	S	D	D	K	R	T	E	M	H	D	D	T	L	D	K	V	P	V	K	W	L	A	P	E	V	M	Q	D	K	L	.	.	Y	S	L	K	S	D	V	W	A	F	G	V	L	M	W	E	I	Y	A	D	G	A	D	P	Y	P	G	M	T	N	.	L	V	T	R	A	K	I	F	C
Query Conservation																																								.	.																															.
Alig confidence															.	.	.	.	.	.	.	.	.	.																.	.																				.											.
Template Conservation															.	.	.	.	.	.	.	.	.	.																																					.
Template Sequence		L	K	I	S	D	F	G	T	S	K	R	L	T	.	.	.	.	.	.	.	.	.	.	G	T	L	Q	Y	M	A	P	E	I	I	D	K	G	P	R	G	Y	G	K	A	A	D	I	W	S	L	G	C	T	I	I	E	M	A	T	.	G	K	P	P	F	Y	E	L	G	E	P	Q	A	A	M	F	K	V	G	M
Template Known Secondary structure								S	S						.	.	.	.	.	.	.	.	.	.			G	G	G										G	G	G		S																		.	S	S		T	T	G	G	G		S
Template Predicted Secondary structure															.	.	.	.	.	.	.	.	.	.																																					.
Template SS confidence
		818	.	820	.	.	.	.	.	.	.	.	.	830											.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.		.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.
		360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	D	Y	R	M	T	F	P	E	T	T	P	P	T	I	S	E	I	A	L	K	Q	C	W	A	K	L	P	S	D	R	A	T	M	K	T	V	H	H
Query Conservation
Alig confidence																				.
Template Conservation																				.
Template Sequence		F	K	V	H	P	E	I	P	E	S	M	S	A	E	A	K	A	F	.	I	L	K	C	F	E	P	D	P	D	K	R	A	C	A	N	D	L	L	V
Template Known Secondary structure			T							T	T	S								.					T		S		T	T	T	S								T
Template Predicted Secondary structure																				.
Template SS confidence
		897	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.		.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D