Job Description Q19726 Confidence 100.00% Date Sat Apr 13 13:19:58 BST 2013 Rank 194 Aligned Residues 255 % Identity 24% Template c3mtfB_ PDB info PDB header:transferase Chain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor Resolution 2.15 Å

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		132	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	N	V	I	F	I	K	K	L	G	E	G	A	F	G	E	V	S	L	A	E	C	E	I	G	G	R	K	V	E	T	A	V	K	T	M	R	C	Q	M	T	R	D	T	R	A	A	F	M	K	E	A	R	L	M	R	K	Y	S	H	P	H	I	V	R	I	I	G	K	I	I	V	K	H	L	P	K	V	G	L
Query Conservation
Alig confidence																										.	.	.	.														.	.																													.	.	.	.	.	.	.
Template Conservation																										.	.	.	.														.	.																													.	.	.	.	.	.	.
Template Sequence		R	D	I	T	L	L	E	C	V	G	K	G	R	Y	G	E	V	W	R	G	S	W	Q	G	.	.	.	.	E	N	V	A	V	K	I	F	S	S	R	D	E	.	.	K	S	W	F	R	E	T	E	L	Y	N	T	V	M	L	R	H	E	N	I	L	G	F	I	A	S	D	M	.	.	.	.	.	.	.	T	S
Template Known Secondary structure		T	T											T	T									T	T	.	.	.	.										G	G	G		.	.													S					T	T	B									.	.	.	.	.	.	.
Template Predicted Secondary structure																										.	.	.	.														.	.																													.	.	.	.	.	.	.
Template SS confidence
		206	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.					230	.	.	.	.	.	.	.	.	.	240	.	.			.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270								.	.
		212	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.									.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.
Predicted Secondary structure																																																								.	.	.	.	.	.	.	.
Query SS confidence																																																								.	.	.	.	.	.	.	.
Query Sequence		A	V	D	A	H	P	L	M	I	V	M	E	M	C	P	H	G	S	L	L	S	F	L	R	K	N	K	G	K	T	T	L	S	E	R	L	R	F	C	I	E	S	A	D	G	L	A	Y	L	E	K	K	Q	C	.	.	.	.	.	.	.	.	L	H	R	D	I	A	A	R	N	C	L	L	S	I	T	D	Q	I
Query Conservation																																																								.	.	.	.	.	.	.	.
Alig confidence																									.	.																														.	.	.	.	.	.	.	.
Template Conservation																									.	.
Template Sequence		R	H	S	S	T	Q	L	W	L	I	T	H	Y	H	E	M	G	S	L	Y	D	Y	L	.	.	Q	L	T	T	L	D	T	V	S	C	L	R	I	V	L	S	I	A	S	G	L	A	H	L	H	I	E	I	F	G	T	Q	G	K	P	A	I	A	H	R	D	L	K	S	K	N	I	L	V	K	K	N	G	Q	C
Template Known Secondary structure			T	T												T	T		B						.	.					B																					S		B		S	T	T		B						S			S	G	G	G					T	T	S
Template Predicted Secondary structure																									.	.
Template SS confidence
		273	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.			.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
		284	.	.	.	.	.	290	.	.	.	.					.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320							.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Predicted Secondary structure													.	.	.	.																											.	.	.	.	.	.																															.	.	.
Query SS confidence													.	.	.	.																											.	.	.	.	.	.																															.	.	.
Query Sequence		K	I	S	D	F	G	L	S	D	D	K	.	.	.	.	R	T	E	M	H	D	D	T	L	D	K	V	P	V	K	W	L	A	P	E	V	M	Q	D	K	L	.	.	.	.	.	.	Y	S	L	K	S	D	V	W	A	F	G	V	L	M	W	E	I	Y	A	D	G	A	D	P	Y	P	G	M	T	N	.	.	.
Query Conservation													.	.	.	.																											.	.	.	.	.	.																															.	.	.
Alig confidence													.	.	.	.																											.	.	.	.	.	.																				.											.	.	.
Template Conservation																																																																				.
Template Sequence		C	I	A	D	L	G	L	A	V	M	H	S	Q	S	T	N	Q	L	D	V	G	N	N	P	R	V	G	T	K	R	Y	M	A	P	E	V	L	D	E	T	I	Q	V	D	C	F	D	S	Y	K	R	V	D	I	W	A	F	G	L	V	L	W	E	V	A	R	.	R	M	V	S	N	G	I	V	E	D	Y	K	P
Template Known Secondary structure							T	T						T	T	T	T													G	G	G							T	T				T	T																						T	.	T	B		B	T	T	B
Template Predicted Secondary structure																																																																				.
Template SS confidence
		351	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.		.	.	.	420	.	.	.	.	.	.	.	.	.
														351	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.						370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.																				.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.																				.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	L	V	T	R	A	K	I	F	C	D	D	Y	R	M	T	F	P	E	T	.	.	.	.	.	T	P	P	T	I	S	E	I	A	L	K	Q	C	W	A	K	L	P	S	D	R	A	T	M	K	T	V	H	H	K	L	K	D	L
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.																				.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.																				.	.	.	.	.									.
Template Conservation																																														.
Template Sequence		P	F	Y	D	V	V	P	N	D	P	S	F	E	D	M	R	K	V	V	C	V	D	Q	Q	R	P	N	I	P	N	R	W	F	S	D	P	T	L	T	S	L	A	K	L	.	M	K	E	C	W	Y	Q	N	P	S	A	R	L	T	A	L	R	I	K	K	T	L	T	K	I
Template Known Secondary structure		T	T	T	T	T	S		S	S											T	T	S								G	G	G	G	G	S										.							S	S	G	G	G	S
Template Predicted Secondary structure																																														.
Template SS confidence
		430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.		.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D