Job Description Q19726 Confidence 100.00% Date Sat Apr 13 13:19:58 BST 2013 Rank 40 Aligned Residues 263 % Identity 29% Template c3lxkA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 Resolution 2.00 Å

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		129	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.			.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.
Predicted Secondary structure																												.	.
Query SS confidence																												.	.
Query Sequence		I	S	H	E	N	V	I	F	I	K	K	L	G	E	G	A	F	G	E	V	S	L	A	E	C	E	.	.	I	G	G	R	K	V	E	T	A	V	K	T	M	R	C	Q	M	T	R	D	T	R	A	A	F	M	K	E	A	R	L	M	R	K	Y	S	H	P	H	I	V	R	I	I	G	K	I	I	V	K	H	L
Query Conservation																												.	.
Alig confidence																												.	.															.
Template Conservation																																												.
Template Sequence		F	E	E	R	H	L	K	Y	I	S	Q	L	G	K	G	N	F	G	S	V	E	L	C	R	Y	D	P	L	G	D	N	T	G	A	L	V	A	V	K	Q	L	Q	.	H	S	G	P	D	Q	Q	R	D	F	Q	R	E	I	Q	I	L	K	A	L	H	S	D	F	I	V	K	Y	R	G	V	S	Y	G	P	G	R
Template Known Secondary structure				G	G	G											T	T										T	T	S	S	S		S									S	.	S																		T				T	T	B									S	S	S	S
Template Predicted Secondary structure																																												.
Template SS confidence
		817	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.		.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.
		207	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	K	V	G	L	A	V	D	A	H	P	L	M	I	V	M	E	M	C	P	H	G	S	L	L	S	F	L	R	K	N	K	G	K	T	T	L	S	E	R	L	R	F	C	I	E	S	A	D	G	L	A	Y	L	E	K	K	Q	C	L	H	R	D	I	A	A	R	N	C	L	L	S	I	T	D	Q	I	K	I	S
Query Conservation
Alig confidence				.	.	.	.	.	.	.	.	.
Template Conservation				.	.	.	.	.	.	.	.	.
Template Sequence		Q	S	.	.	.	.	.	.	.	.	.	L	R	L	V	M	E	Y	L	P	S	G	C	L	R	D	F	L	Q	R	H	R	A	R	L	D	A	S	R	L	L	L	Y	S	S	Q	I	C	K	G	M	E	Y	L	G	S	R	R	C	V	H	R	D	L	A	A	R	N	I	L	V	E	S	E	A	H	V	K	I	A
Template Known Secondary structure				.	.	.	.	.	.	.	.	.									T	T		B									G	G	G																							T	T				S			S	G	G	G						T	T
Template Predicted Secondary structure				.	.	.	.	.	.	.	.	.
Template SS confidence
		896	.										.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.
		287	.	.	290	.	.	.	.				.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.										.	.	350	.	.	.	.
Predicted Secondary structure										.	.	.																																																						.	.	.	.	.	.	.	.	.
Query SS confidence										.	.	.																																																						.	.	.	.	.	.	.	.	.
Query Sequence		D	F	G	L	S	D	D	K	.	.	.	R	T	E	M	H	D	D	T	L	D	K	V	P	V	K	W	L	A	P	E	V	M	Q	D	K	L	Y	S	L	K	S	D	V	W	A	F	G	V	L	M	W	E	I	Y	A	D	G	A	D	P	Y	P	G	.	.	.	.	.	.	.	.	.	M	T	N	L	V	T	R
Query Conservation										.	.	.																																																						.	.	.	.	.	.	.	.	.
Alig confidence										.	.	.																																														.								.	.	.	.	.	.	.	.	.
Template Conservation																																																										.
Template Sequence		D	F	G	L	A	K	L	L	P	L	D	K	D	Y	Y	V	V	R	E	P	G	Q	S	P	I	F	W	Y	A	P	E	S	L	S	D	N	I	F	S	R	Q	S	D	V	W	S	F	G	V	V	L	Y	E	L	F	T	.	Y	C	D	K	S	C	S	P	S	A	E	F	L	R	M	M	V	P	A	L	S	R	L
Template Known Secondary structure				T	T						T	T		S					S	S				S		G	G	G																													T	.	T	T		G	G	G	S
Template Predicted Secondary structure																																																										.
Template SS confidence
		967	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.		.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.
		355	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	K	I	F	C	D	D	Y	R	M	T	F	P	E	T	T	P	P	T	I	S	E	I	A	L	K	Q	C	W	A	K	L	P	S	D	R	A	T	M	K	T	V	H	H	K	L	K	D	L
Query Conservation
Alig confidence																									.
Template Conservation																									.
Template Sequence		L	E	L	L	E	E	G	Q	R	L	P	A	P	P	A	C	P	A	E	V	H	E	L	.	M	K	L	C	W	A	P	S	P	Q	D	R	P	S	F	S	A	L	G	P	Q	L	D	M	L
Template Known Secondary structure							T	T							T	T									.					T		S	S	G	G	G	S
Template Predicted Secondary structure																									.
Template SS confidence
		1051	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.		.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D