Job Description Q19726 Confidence 100.00% Date Sat Apr 13 13:19:58 BST 2013 Rank 218 Aligned Residues 246 % Identity 22% Template c3kvwA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand Resolution 2.28 Å

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		132	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.							.	.	.	.	.	.	.	.	200	.	.	.	.	.
Predicted Secondary structure																																																														.	.	.	.	.	.
Query SS confidence																																																														.	.	.	.	.	.
Query Sequence		E	N	V	I	F	I	K	K	L	G	E	G	A	F	G	E	V	S	L	A	E	C	E	I	G	G	R	K	V	E	T	A	V	K	T	M	R	C	Q	M	T	R	D	T	R	A	A	F	M	K	E	A	R	L	M	R	K	Y	S	H	.	.	.	.	.	.	P	H	I	V	R	I	I	G	K	I	I	V	K	H
Query Conservation																																																														.	.	.	.	.	.
Alig confidence																												.	.										.	.																						.	.	.	.	.	.
Template Conservation																												.	.										.	.
Template Sequence		Y	R	Y	E	V	L	K	V	I	G	K	G	S	F	G	Q	V	V	K	A	Y	D	H	K	V	H	.	.	Q	H	V	A	L	K	M	V	R	.	.	N	E	K	R	F	H	R	Q	A	A	E	E	I	R	I	L	E	H	L	R	K	Q	D	K	D	N	T	M	N	V	I	H	M	L	E	N	F	T	F	R	N
Template Known Secondary structure		T	T										S	S	S									T	T	T	T	.	.										.	.	S																				T	T		T	T	S		S		B										T	T
Template Predicted Secondary structure																												.	.										.	.
Template SS confidence
		147	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.			.	.	.	.	.	.	.	180	.			.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.
		206	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.			.	.
Predicted Secondary structure																																																																														.	.
Query SS confidence																																																																														.	.
Query Sequence		L	P	K	V	G	L	A	V	D	A	H	P	L	M	I	V	M	E	M	C	P	H	G	S	L	L	S	F	L	R	K	N	K	G	K	T	T	L	S	E	R	L	R	F	C	I	E	S	A	D	G	L	A	Y	L	E	K	K	Q	C	L	H	R	D	I	A	A	R	N	C	L	L	S	I	T	D	.	.	Q	I
Query Conservation																																																																														.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.																																																																		.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	H	I	C	M	T	F	E	L	L	S	M	N	L	Y	E	L	I	K	K	N	K	F	Q	G	F	S	L	P	L	V	R	K	F	A	H	S	I	L	Q	C	L	D	A	L	H	K	N	R	I	I	H	C	D	L	K	P	E	N	I	L	L	K	Q	Q	G	R	S	G	I
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.												B								T	T	T																										T				S			S	G	G	G				S	S	T	T	S
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
													223	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.
		284	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	I	S	D	F	G	L	S	D	D	K	R	T	E	M	H	D	D	T	L	D	K	V	P	V	K	W	L	A	P	E	V	M	Q	D	K	L	Y	S	L	K	S	D	V	W	A	F	G	V	L	M	W	E	I	Y	A	D	G	A	D	P	Y	P	G	M	T	N	L	V	T	R	A	K	I	F	C	D	D	Y	R
Query Conservation
Alig confidence																								.	.	.	.																															.
Template Conservation																								.	.	.	.																															.
Template Sequence		K	V	I	D	F	G	S	S	C	Y	E	H	Q	R	V	Y	T	I	Q	S	R	F	.	.	.	.	Y	R	A	P	E	V	I	L	G	A	R	Y	G	M	P	I	D	M	W	S	L	G	C	I	L	A	E	L	L	T	.	G	Y	P	L	L	P	G	E	D	E	G	D	Q	L	A	C	M	I	E	L	L	G	M
Template Known Secondary structure							T	T				T	T									G	G	.	.	.	.	G								T	B				T																	.	S	S		S	S			S	S
Template Predicted Secondary structure																								.	.	.	.																															.
Template SS confidence
		292	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.					.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.		.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.
		364	.																																																							.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.
Predicted Secondary structure				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		M	T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	F	P	E	T	T	P	P	T	I	S	E	I	A	L	K	Q	C	W	A	K	L	P	S	D
Query Conservation				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													.
Template Conservation																																																																						.
Template Sequence		P	S	Q	K	L	L	D	A	S	K	R	A	K	N	F	V	S	K	G	Y	P	R	Y	C	T	V	T	T	L	S	D	V	V	L	N	G	G	R	S	R	R	G	K	L	R	G	P	P	E	S	R	E	W	G	N	A	L	K	G	C	D	D	P	L	F	L	D	F	.	L	K	Q	C	L	E	W	D	P	A	V
Template Known Secondary structure									T	B	T	T					B					B	T	T	S																T	T						S	T	T		S						T	T	T										.					T		S	S	T	T	T
Template Predicted Secondary structure																																																																						.
Template SS confidence
		368	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.		.	.	.	.	440	.	.	.	.	.	.
		390	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	A	T	M	K	T	V	H	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	M	T	P	G	Q	A	L	R
Template Known Secondary structure		S								T
Template Predicted Secondary structure
Template SS confidence
		450	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D