Job Description Q19726 Confidence 100.00% Date Sat Apr 13 13:19:58 BST 2013 Rank 137 Aligned Residues 241 % Identity 37% Template c3k54A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases. Resolution 1.94 Å

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		125	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	D	W	I	I	S	H	E	N	V	I	F	I	K	K	L	G	E	G	A	F	G	E	V	S	L	A	E	C	E	I	G	G	R	K	V	E	T	A	V	K	T	M	R	C	Q	M	T	R	D	T	R	A	A	F	M	K	E	A	R	L	M	R	K	Y	S	H	P	H	I	V	R	I	I	G	K	I	I	V	K
Query Conservation
Alig confidence																																			.	.	.									.	.	.	.	.	.	.	.	.
Template Conservation																																			.	.	.									.	.	.	.	.	.	.	.	.
Template Sequence		G	S	W	E	I	D	P	K	D	L	T	F	L	K	E	L	G	T	G	Q	F	G	V	V	K	Y	G	K	W	R	G	Q	Y	.	.	.	D	V	A	I	K	M	I	K	.	.	.	.	.	.	.	.	.	E	F	I	E	E	A	K	V	M	M	N	L	S	H	E	K	L	V	Q	L	Y	G	V	C	T	K	Q
Template Known Secondary structure		G	G	G	B			G	G	G									S	T	T	S	S								T	T	T		.	.	.									.	.	.	.	.	.	.	.	.			T	T											T	T	B									S	S
Template Predicted Secondary structure																																			.	.	.									.	.	.	.	.	.	.	.	.
Template SS confidence
		393	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.				.	.	.	.	430	.	.	.										.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460
		205	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	L	P	K	V	G	L	A	V	D	A	H	P	L	M	I	V	M	E	M	C	P	H	G	S	L	L	S	F	L	R	K	N	K	G	K	T	T	L	S	E	R	L	R	F	C	I	E	S	A	D	G	L	A	Y	L	E	K	K	Q	C	L	H	R	D	I	A	A	R	N	C	L	L	S	I	T	D	Q	I	K
Query Conservation
Alig confidence				.	.	.	.	.	.	.	.	.	.	.
Template Conservation				.	.	.	.	.	.	.	.	.	.	.
Template Sequence		R	P	.	.	.	.	.	.	.	.	.	.	.	I	F	I	I	T	E	Y	M	A	N	G	C	L	L	N	Y	L	R	E	M	R	H	R	F	Q	T	Q	Q	L	L	E	M	C	K	D	V	C	E	A	M	E	Y	L	E	S	K	Q	F	L	H	R	D	L	A	A	R	N	C	L	V	N	D	Q	G	V	V	K
Template Known Secondary structure		S	S	.	.	.	.	.	.	.	.	.	.	.									T	T										G	G	G																								T	T				S			S	G	G	G					T	T
Template Predicted Secondary structure				.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		468	.												470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.
		285	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	S	D	F	G	L	S	D	D	K	R	T	E	M	H	D	D	T	L	D	K	V	P	V	K	W	L	A	P	E	V	M	Q	D	K	L	Y	S	L	K	S	D	V	W	A	F	G	V	L	M	W	E	I	Y	A	D	G	A	D	P	Y	P	G	M	T	N	L	V	T	R	A	K	I	F	C	D	D	Y	R	M
Query Conservation
Alig confidence									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																																					.
Template Conservation									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																																					.
Template Sequence		V	S	D	F	G	F	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	V	R	W	S	P	P	E	V	L	M	Y	S	K	F	S	S	K	S	D	I	W	A	F	G	V	L	M	W	E	I	Y	S	L	G	K	M	P	Y	E	R	F	T	N	S	E	T	A	E	H	I	A	Q	.	G	L	R	L
Template Known Secondary structure									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	G	G																													T	T	S			T	T	T	T	S											T	.	T
Template Predicted Secondary structure									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																																					.
Template SS confidence
		537	.	.	540	.	.	.																	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.		.	.	.	.
		365	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	F	P	E	T	T	P	P	T	I	S	E	I	A	L	K	Q	C	W	A	K	L	P	S	D	R	A	T	M	K	T	V	H	H	K	L	K	D	L	S	M	P
Query Conservation
Alig confidence															.
Template Conservation															.
Template Sequence		Y	R	P	H	L	A	S	E	K	V	Y	T	I	.	M	Y	S	C	W	H	E	K	A	D	E	R	P	T	F	K	I	L	L	S	N	I	L	D	V	M	D	E
Template Known Secondary structure					T	T	S								.				T	T		S	S	G	G	G	S
Template Predicted Secondary structure															.
Template SS confidence
		617	.	.	620	.	.	.	.	.	.	.	.	.		630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D