|   |   |
128 | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
I | I | S | H | E | N | V | I | F | I | K | K | L | G | E | G | A | F | G | E | V | S | L | A | E | C | E | I | G | G | R | K | V | E | T | A | V | K | T | M | R | C | Q | M | T | R | D | T | R | A | A | F | M | K | E | A | R | L | M | R | K | Y | S | H | P | H | I | V | R | I | I | G | K | I | I | V | K | H | L | P |
| Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
| Template Conservation |   |
  |
|   |   |
|   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   | . | . |   |   |
|
|
|
|   |
|   |   |   | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   | . |
| Template Sequence |   |
E | V | K | A | D | D | L | E | P | I | M | E | L | G | R | G | A | Y | G | V | V | E | K | M | R | H | V | P | S | G | . |
. |
Q | I | M | A | V | K | R | I | R | N | S | . |
. |
Q | E | Q | K | R | L | L | M | D | L | D | I | S | M | R | T | V | D | C | P | F | T | V | T | F | Y | G | A | L | F | R | E | G | D | . |
| Template Known Secondary structure |   |
|
|
| G | G | G |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | T | T | . | . |  |  |  |  |  |  |  |  |
|
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| T | T | B |
|
|  |  |  |  |  |  |
| S | S | S | . |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |  |  |  |  |
|
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
| . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
47 | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | |
|
. | . | . | 80 | . | . | . | . | . | . | . | |
|
. | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | |
|   |
|   |   |
208 | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | |
|
. | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | |
. | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | V | G | L | A | V | D | A | H | P | L | M | I | V | M | E | M | C | P | H | G | . |
. |
S | L | L | S | F | L | R | K | N | K | G | K | T | T | L | S | E | R | L | R | F | C | I | E | S | A | D | G | L | A | Y | L | E | K | K | . |
Q | C | L | H | R | D | I | A | A | R | N | C | L | L | S | I | T | D | Q | I | K |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   | . |   |   |
|
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|
| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. | . | . | . | . | . | . | . | . | . |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | W | I | C | M | E | L | M | D | T | S | L | D | K | F | Y | K | Q | V | I | D | K | G | Q | T | I | P | E | D | I | L | G | K | I | A | V | S | I | V | K | A | L | E | H | L | H | S | K | L | S | V | I | H | R | D | V | K | P | S | N | V | L | I | N | A | L | G | Q | V | K |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|
|
|
| S | G | G | G |
|  |  |
| T | T |
|
|  |  |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|
|
|
|
|
125 | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . |
|   |
|   |   |
285 | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | |
|
. | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
| . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
I | S | D | F | G | L | S | D | D | K | R | T | E | M | H | D | D | T | L | D | K | V | P | V | K | W | L | A | P | E | V | M | Q | D | K | L | . |
. |
Y | S | L | K | S | D | V | W | A | F | G | V | L | M | W | E | I | Y | A | D | G | A | D | P | Y | P | G | M | T | N | L | V | T | R | A | K | I | F | C | D | D | Y |
| Query Conservation |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   | . | . |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|
| . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
M | C | D | F | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | C | K | P | Y | M | A | P | E | R | I | N | P | E | L | N | Q | Y | S | V | K | S | D | I | W | S | L | G | I | T | M | I | E | L | A | I | . |
L | R | F | P | Y | D | S | W | G | T | P | F | Q | Q | L | K | Q | V | V | E | E | P |
| Template Known Secondary structure |   |
B |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
| S |
|  |  |  |  | S |
|
| T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | T | S |
| S | S |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  | S |
|
| Template Predicted Secondary structure |   |
 |  |
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
195 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | |
. | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . |
|   |
|   |   |
363 | . | . | . | . | . | |
. | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | M | T | F | P | E | . |
T | T | P | P | T | I | S | E | I | A | L | K | Q | C | W | A | K | L | P | S | D | R | A | T | M | K | T | V | H | H |
| Query Conservation |   |
  |   |   |   |
|   | . |   |   |
|   |   |
|   |   |
|   |
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |
|
|   |   |
| Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
| . |
|   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |
|
|
|   |
| Template Sequence |   |
S | P | Q | L | P | A | D | K | F | S | A | E | F | V | D | F | . |
T | S | Q | C | L | K | K | N | S | K | E | R | P | T | Y | P | E | L | M | Q |
| Template Known Secondary structure |   |
|
|
|
|
| T | T | T | S |
|  |  |  |  |  |  | . |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  | T | T |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  | . |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
275 | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | |
. | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 |
|   |