Job Description Q19726 Confidence 100.00% Date Sat Apr 13 13:19:58 BST 2013 Rank 284 Aligned Residues 261 % Identity 18% Template c2vagA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity protein kinase clk1; PDBTitle: crystal structure of di-phosphorylated human clk1 in2 complex with a novel substituted indole inhibitor Resolution 1.80 Å

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		128	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	I	S	H	E	N	V	I	F	I	K	K	L	G	E	G	A	F	G	E	V	S	L	A	E	C	E	I	G	G	R	K	V	E	T	A	V	K	T	M	R	C	Q	M	T	R	D	T	R	A	A	F	M	K	E	A	R	L	M	R	K	Y	S	H	P	H	I	V	R	I	I	G	K	I	I	V	K	H	L	P
Query Conservation
Alig confidence																																			.								.	.																																			.	.	.
Template Conservation																																			.								.	.																																			.	.	.
Template Sequence		D	V	L	S	A	R	Y	E	I	V	D	T	L	G	E	G	A	F	G	K	V	V	E	C	I	D	H	K	A	G	G	R	H	.	V	A	V	K	I	V	K	.	.	N	V	D	R	Y	C	E	A	A	R	S	E	I	Q	V	L	E	H	L	N	T	T	D	P	N	S	T	F	R	C	V	Q	M	L	.	.	.
Template Known Secondary structure					T	T	T											T	T									T	T	T	T	T			.								.	.	S	S																						T	T		T	T		B					.	.	.
Template Predicted Secondary structure																																			.								.	.																																			.	.	.
Template SS confidence
		155	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.		.	.	190	.	.	.	.			.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.
		208	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	V	G	L	A	V	D	A	H	P	L	M	I	V	M	E	M	C	P	H	G	S	L	L	S	F	L	R	K	N	K	G	K	T	T	L	S	E	R	L	R	F	C	I	E	S	A	D	G	L	A	Y	L	E	K	K	Q	C	L	H	R	D	I	A	A	R	N	C	L	L	S	I	T	D	Q	I	K	I	S	D
Query Conservation
Alig confidence		.	.
Template Conservation		.	.
Template Sequence		.	.	E	W	F	E	H	H	G	H	I	C	I	V	F	E	L	L	G	L	S	T	Y	D	F	I	K	E	N	G	F	L	P	F	R	L	D	H	I	R	K	M	A	Y	Q	I	C	K	S	V	N	F	L	H	S	N	K	L	T	H	T	D	L	K	P	E	N	I	L	F	V	Q	S	D	Y	T	E	A	Y	N
Template Known Secondary structure		.	.						T	T												B								T	T	T																									T	T								G	G	G				S
Template Predicted Secondary structure		.	.
Template SS confidence
				229	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.
		288	.	290	.	.												.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.
Predicted Secondary structure							.	.	.	.	.	.	.	.	.	.	.
Query SS confidence							.	.	.	.	.	.	.	.	.	.	.
Query Sequence		F	G	L	S	D	.	.	.	.	.	.	.	.	.	.	.	D	K	R	T	E	M	H	D	D	T	L	D	K	V	P	V	K	W	L	A	P	E	V	M	Q	D	K	L	Y	S	L	K	S	D	V	W	A	F	G	V	L	M	W	E	I	Y	A	D	G	A	D	P	Y	P	G	M	T	N	L	V	T	R	A	K
Query Conservation							.	.	.	.	.	.	.	.	.	.	.
Alig confidence							.	.	.	.	.	.	.	.	.	.	.																																																.
Template Conservation																																																																	.
Template Sequence		K	R	D	E	R	T	L	I	N	P	D	I	K	V	V	D	F	G	S	A	T	Y	D	D	E	H	H	S	T	L	V	R	H	Y	R	A	P	E	V	I	L	A	L	G	W	S	Q	P	C	D	V	W	S	I	G	C	I	L	I	E	Y	Y	L	.	G	F	T	V	F	P	T	H	D	S	K	E	H	L	A	M
Template Known Secondary structure									S										S	S				T	T	S				S					S							T	T	S			S	T																	.	S	S		S				S
Template Predicted Secondary structure																																																																	.
Template SS confidence
		310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.		.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.
		357	.	.	360	.	.	.	.	.																																											.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.
Predicted Secondary structure											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		I	F	C	D	D	Y	R	M	T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	F	P	E	T	T	P	P	T	I	S	E	I	A	L	K	Q	C	W	A	K	L	P	S	D	R	A	T	M	K
Query Conservation											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													.
Template Conservation																																																																	.
Template Sequence		M	E	R	I	L	G	P	L	P	K	H	M	I	Q	K	T	R	K	R	K	Y	F	H	H	D	R	L	D	W	D	E	H	S	S	A	G	R	Y	V	S	R	A	C	K	P	L	K	E	F	M	L	S	Q	D	V	E	H	E	R	L	F	D	L	.	I	Q	K	M	L	E	Y	D	P	A	K	R	I	T	L	R
Template Known Secondary structure								S										S		G	G	G			T	T						T	T	S													G	G	G	G		S			S										.					T		S	S	T	T	T	S
Template Predicted Secondary structure																																																																	.
Template SS confidence
		391	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.		.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.
		395	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	V	H	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	A	L	K
Template Known Secondary structure				T	T
Template Predicted Secondary structure
Template SS confidence
		470	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D