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Job DescriptionQ19726
Confidence100.00%DateSat Apr 13 13:19:58 BST 2013
Rank76Aligned Residues253
% Identity26%Templatec2j51A_
PDB info PDB header:transferaseChain: A: PDB Molecule:ste20-like serine/threonine-protein kinase; PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide
Resolution2.1 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   130.........140.........150.........160.........170.........180.........190.........200.........
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Query Sequence  SHENVIFIKKLGEGAFGEVSLAECEIGGRKVETAVKTMRCQMTRDTRAAFMKEARLMRKYSHPHIVRIIGKIIVKHLPKV
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Template Sequence  PEDFWEIIGELGDGAFGKVYKAQNKETSV. . LAAAKVIDTKSEE. ELEDYMVEIDILASCDHPNIVKLLDAFYYEN. . . .
Template Known Secondary structure  GGGTTTTTT

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   30.........40.........50........ .60.........70. ........80.........90.........100..
 
   210.........220.........230.........240.........250.........260.........270.........280.........
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Query Sequence  GLAVDAHPLMIVMEMCPHGSLLSFLRKNKGKTTLSERLRFCIESADGLAYLEKKQCLHRDIAARNCLLSITDQIKISDFG
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Template Sequence  . . . . . . . NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFG
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   103......110.........120.........130.........140.........150.........160.........170.....
 
   290.........300.........310...... ...320.........330.........340.........350.........360.. .
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Query Sequence  LSDDKRTEMHDDTLDKVPVKWLAPEVM. . . . . QDKLYSLKSDVWAFGVLMWEIYADGADPYPGMTNLVTRAKIFCDDY. R
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Template Sequence  VSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE. IEPPHHELNPMRVLLKIAKSEPPT
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   176...180.........190.........200.........210.........220.........230 .........240.........250....
 
   364.....370.........380.........390........
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Query Sequence  MTFPETTPPTISEIALKQCWAKLPSDRATMKTVHH
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Template Sequence  LAQPSRWSSNFKDF. LKKCLEKNVDARWTTSQLLQ
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   255....260........ .270.........280........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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