|   |   |
130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
S | H | E | N | V | I | F | I | K | K | L | G | E | G | A | F | G | E | V | S | L | A | E | C | E | I | G | G | R | K | V | E | T | A | V | K | T | M | R | C | Q | M | T | R | D | T | R | A | A | F | M | K | E | A | R | L | M | R | K | Y | S | H | P | H | I | V | R | I | I | G | K | I | I | V | K | H | L | P | K | V |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
| Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |
|   |   | . | . |   |
|
|
|
|   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   | . | . | . | . |
| Template Sequence |   |
P | R | L | L | L | D | S | Y | V | K | I | G | E | G | S | T | G | I | V | C | L | A | R | E | K | H | S | G | R | . |
. |
Q | V | A | V | K | M | M | D | L | R | K | Q | Q | . |
R | R | E | L | L | F | N | E | V | V | I | M | R | D | Y | Q | H | F | N | V | V | E | M | Y | K | S | Y | L | V | G | E | . |
. |
. |
. |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T | T |
|
| . | . |  |  |  |  |  |  |  |  | T | T | T |
|
| . | S |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| T | T | B |
|
|  |  |  |  |  |  |  | T | T | . | . | . | . |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
403 | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | |
|
. | . | . | . | . | . | . | . | 440 | . | . | . | . | |
. | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | |
|
|
|
|   |
|   |   |
210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | L | A | V | D | A | H | P | L | M | I | V | M | E | M | C | P | H | G | S | L | L | S | F | L | R | K | N | K | G | K | T | T | L | S | E | R | L | R | F | C | I | E | S | A | D | G | L | A | Y | L | E | K | K | Q | C | L | H | R | D | I | A | A | R | N | C | L | L | S | I | T | D | Q | I | K | I | S | D | F | G |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |
|
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
| Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. | . | . | . | . | . | . |   |   |   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
E | L | W | V | L | M | E | F | L | Q | G | G | A | L | T | D | I | V | S | Q | V | R | . |
. |
L | N | E | E | Q | I | A | T | V | C | E | A | V | L | Q | A | L | A | Y | L | H | A | Q | G | V | I | H | R | D | I | K | S | D | S | I | L | L | T | L | D | G | R | V | K | L | S | D | F | G |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
| S |
| B |  |  |  |  |  | T | T |
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
|
|
|
| S | G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
|
| T |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|
|
476 | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | |
|
. | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . |
|   |
|   |   |
290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | |
. | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| Query Sequence |   |
L | S | D | D | K | R | T | E | M | H | D | D | T | L | D | K | V | P | V | K | W | L | A | P | E | V | M | Q | D | K | L | Y | S | L | K | S | D | V | W | A | F | G | V | L | M | W | E | I | Y | A | D | G | A | D | P | Y | P | G | M | T | N | L | V | T | R | A | K | I | F | C | D | D | Y | . |
R | M | T | F | P | E |
| Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|
|   |
| . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
F | C | A | Q | I | S | K | . |
D | V | P | K | R | K | L | V | G | T | P | Y | W | M | A | P | E | V | I | S | R | S | L | Y | A | T | E | V | D | I | W | S | L | G | I | M | V | I | E | M | V | D | . |
G | E | P | P | Y | F | S | D | S | P | V | Q | A | M | K | R | L | R | D | S | P | P | P | K | L | K | N | S | H |
| Template Known Secondary structure |   |
T |
|  |  |
|
| S | . | S | S |
|
| B |
|
|
| S |
| G | G | G |
|
|  |  |  |  | T | T |
|
| B |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| T | T | T | T | S |
|  |  |  |  |  |  |  |  |  |  | S | S |
|
|
|
| T | T | G | G |
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|
| . |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
547 | . | . | 550 | . | . | . | |
. | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | |
. | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . |
|   |
|   |   |
369 | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
T | T | P | P | T | I | S | E | I | A | L | K | Q | C | W | A | K | L | P | S | D | R | A | T | M | K | T | V | H | H |
| Query Conservation |   |
  |   |
|   |   |
|   |   |
|   |
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |
|
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |   |
| . |
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
| Template Sequence |   |
K | V | S | P | V | L | R | D | F | . |
L | E | R | M | L | V | R | D | P | Q | E | R | A | T | A | Q | E | L | L | D |
| Template Known Secondary structure |   |
G | S |
|  |  |  |  |  |  | . |  |  |  |  | S |
| S | S | T | T | T | S |
|
|  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  | . |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
626 | . | . | . | 630 | . | . | . | . | |
. | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . |
|   |