Job Description Q19726 Confidence 100.00% Date Sat Apr 13 13:19:58 BST 2013 Rank 6 Aligned Residues 373 % Identity 32% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å Model Dimensions (Å) X:74.091 Y:76.156 Z:48.417

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		7	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.					.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.						.	70	.	.	.	.	.	.	.
Predicted Secondary structure																																									.	.	.	.																								.	.	.	.	.
Query SS confidence																																									.	.	.	.																								.	.	.	.	.
Query Sequence		A	T	D	S	S	S	S	T	S	S	M	T	E	N	S	D	G	Q	K	Q	N	N	E	W	F	H	G	V	L	Q	R	Q	D	A	D	E	L	L	V	.	.	.	.	K	P	G	S	F	L	L	R	A	S	E	V	H	G	K	M	S	M	I	L	S	V	R	.	.	.	.	.	H	D	G	K	L	H	N	I	A
Query Conservation																																									.	.	.	.																								.	.	.	.	.
Alig confidence																																									.	.	.	.														.										.	.	.	.	.
Template Conservation																																																										.
Template Sequence		A	T	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	D	S	L	E	T	E	E	W	F	F	K	G	I	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	.	K	G	S	Y	S	L	S	V	R	D	Y	D	P	R	Q	G	D	T	V	K	H	Y	K
Template Known Secondary structure		T	T								G	G	G				T	T	S	G	G	G	S	T	T			T	T											T	S	T	T			T	T								S	S	S	.	T	T											T	T	T
Template Predicted Secondary structure																																																										.
Template SS confidence
		100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.		.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.
		78	.	80	.	.	.	.	.	.	.	.	.		90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.						.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.
Predicted Secondary structure														.																																					.	.	.	.	.
Query SS confidence														.																																					.	.	.	.	.
Query Sequence		V	N	S	D	T	G	E	N	F	W	F	E	.	G	H	R	E	K	S	I	D	Q	L	V	Q	W	H	M	T	T	S	T	P	I	T	K	T	S	G	V	K	L	K	Y	P	I	G	K	A	.	.	.	.	.	D	W	I	I	S	H	E	N	V	I	F	I	K	K	L	G	E	G	A	F	G	E	V	S	L	A
Query Conservation														.																																					.	.	.	.	.
Alig confidence														.																																					.	.	.	.	.
Template Conservation
Template Sequence		I	R	T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L	C	Q	K	L	S	V	P	C	M	S	S	K	P	Q	K	P	W	E	K	D	A	W	E	I	P	R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A
Template Known Secondary structure			B			S	T	T				S	S	T	T	S			S	S								T	T	S	S		S	S		S	S				S	B												T	T		S	B			G	G	G											T	T
Template Predicted Secondary structure
Template SS confidence
		179	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.
		152	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	C	E	I	G	G	R	K	V	E	T	A	V	K	T	M	R	C	Q	M	T	R	D	T	R	A	A	F	M	K	E	A	R	L	M	R	K	Y	S	H	P	H	I	V	R	I	I	G	K	I	I	V	K	H	L	P	K	V	G	L	A	V	D	A	H	P	L	M	I	V	M	E	M	C	P	H	G	S	L	L
Query Conservation
Alig confidence								.	.	.													.	.																																.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation								.	.	.													.	.																																.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		T	Y	N	K	H	T	.	.	.	K	V	A	V	K	T	M	K	P	G	S	M	.	.	S	V	E	A	F	L	A	E	A	N	V	M	K	T	L	Q	H	D	K	L	V	K	L	H	A	V	V	T	K	E	P	.	.	.	.	.	.	.	.	.	.	.	.	I	Y	I	I	T	E	F	M	A	K	G	S	L	L
Template Known Secondary structure				T	T	T		.	.	.											S	S	.	.														T				T	T	B									S	S	S	.	.	.	.	.	.	.	.	.	.	.	.									T	T		B
Template Predicted Secondary structure								.	.	.													.	.																																.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		259	260	.	.	.	.				.	.	.	.	.	270	.	.	.	.	.	.			.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.													.	.	310	.	.	.	.	.	.	.	.	.	320	.
		232	.	.	.		.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310
Predicted Secondary structure						.
Query SS confidence						.
Query Sequence		S	F	L	R	.	K	N	K	G	K	T	T	L	S	E	R	L	R	F	C	I	E	S	A	D	G	L	A	Y	L	E	K	K	Q	C	L	H	R	D	I	A	A	R	N	C	L	L	S	I	T	D	Q	I	K	I	S	D	F	G	L	S	D	D	K	R	T	E	M	H	D	D	T	L	D	K	V	P	V	K	W
Query Conservation						.
Alig confidence						.																																																												.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																																		.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	V	I	.	.	.	.	.	.	.	.	.	.	.	.	P	I	K	W
Template Known Secondary structure						S	T	T	G	G	G																							T	T				S			S	G	G	G					T	T								T	T	G	G	G	T		.	.	.	.	.	.	.	.	.	.	.	.		G	G	G
Template Predicted Secondary structure																																																																		.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		322	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.													.	.	.	.
		311	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390
Predicted Secondary structure
Query SS confidence
Query Sequence		L	A	P	E	V	M	Q	D	K	L	Y	S	L	K	S	D	V	W	A	F	G	V	L	M	W	E	I	Y	A	D	G	A	D	P	Y	P	G	M	T	N	L	V	T	R	A	K	I	F	C	D	D	Y	R	M	T	F	P	E	T	T	P	P	T	I	S	E	I	A	L	K	Q	C	W	A	K	L	P	S	D	R
Query Conservation
Alig confidence																																																	.																				.
Template Conservation																																																	.																				.
Template Sequence		T	A	P	E	A	I	N	F	G	S	F	T	I	K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E	V	I	R	A	L	.	E	R	G	Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	.	M	M	R	C	W	K	N	R	P	E	E	R
Template Known Secondary structure		S																												T	T	T			S	S	T	T											.		T	T							T	T									.					T		S	S	G	G	G	S
Template Predicted Secondary structure																																																	.																				.
Template SS confidence
		403	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.		450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.		.	470	.	.	.	.	.	.	.	.	.	480
		391	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	T	M	K	T	V	H	H	K	L	K	D	L	S	M	P	M	S	D	V	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A	T	E	S	Q	E
Template Known Secondary structure													T	T	T	S		G	G	G
Template Predicted Secondary structure
Template SS confidence
		481	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D