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Job DescriptionQ19726
Confidence100.00%DateSat Apr 13 13:19:58 BST 2013
Rank3Aligned Residues383
% Identity30%Templatec1y57A_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Resolution1.91 Å
Model Dimensions (Å)X:93.309 Y:61.635 Z:49.486

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   7..10.........20.........30.........40...... ...50.........60......... 70.......
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Query Sequence  ATDSSSSTSSMTENSDGQKQNNEWFHGVLQRQDADELLVK. . . . PGSFLLRASEVHGKMSMILSVRH. . . . . DGKLHNIA
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Template Sequence  STGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETT. KGAYCLSVSDFDNAKGLNVKHYK
Template Known Secondary structure  TT

GGGTTSGGGSTTS

T
TT

TT

SSS.TT
TTT
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   125....130.........140.........150.........160.........170.........180 .........190.........200...
 
   78.80......... 90.........100.........110.........120... ......130.........140.........150
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Query Sequence  VNSDTGENFWFE. GHREKSIDQLVQWHMTTSTPITKTSGVKLKYPIG. . . . . . KADWIISHENVIFIKKLGEGAFGEVSL
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Template Sequence  IRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWM
Template Known Secondary structure 
SSS
SSTTSSS

TTSSS



B







SS



TTB

GGGTT
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   204.....210.........220.........230.........240.........250.........260.........270.........280...
 
   151........160.........170.........180.........190.........200.........210.........220.........230
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Query Sequence  AECEIGGRKVETAVKTMRCQMTRDTRAAFMKEARLMRKYSHPHIVRIIGKIIVKHLPKVGLAVDAHPLMIVMEMCPHGSL
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Template Sequence  GTWNGTT. . . RVAIKTLKPGTM. . SPEAFLQEAQVMKKLRHEKLVQLYAVVSEEP. . . . . . . . . . . . IYIVTEYMSKGSL
Template Known Secondary structure  TTT...
TTSS..



TTB


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TT
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   284.....290 .........300.. .......310.........320.........330... ......340......
 
   231........240 .........250.........260.........270.........280.........290.. .......300........
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Query Sequence  LSFLRKNKGK. TTLSERLRFCIESADGLAYLEKKQCLHRDIAARNCLLSITDQIKISDFGLSD. DKRTEMHDDTLDKVPV
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Template Sequence  LDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPI
Template Known Secondary structure  S

TT
S

SGGG
GGG



TT


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   347..350.........360.........370.........380.........390.........400.........410.........420......
 
   309310.........320.........330.........340.........350.........360.........370.........380........
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Query Sequence  KWLAPEVMQDKLYSLKSDVWAFGVLMWEIYADGADPYPGMTNLVTRAKIFCDDYRMTFPETTPPTISEIALKQCWAKLPS
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Template Sequence  KWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV. ERGYRMPCPPECPESLHDL. MCQCWRKEPE
Template Known Secondary structure  GGS




TTS

SSTT

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TT

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   427..430.........440.........450.........460.........470..... ....480.........490.... .....500....
 
   389390.........400.........
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Query Sequence  DRATMKTVHHKLKDLSMPMSD
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Template Sequence  ERPTFEYLQAFLEDYFTSTEP
Template Known Secondary structure  GS

TT
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   505....510.........520.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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