Job Description Q19726 Confidence 100.00% Date Sat Apr 13 13:19:58 BST 2013 Rank 2 Aligned Residues 386 % Identity 31% Template c1oplA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase Resolution 3.42 Å Model Dimensions (Å) X:75.491 Y:62.140 Z:51.181

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.			.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.
Predicted Secondary structure																																											.	.
Query SS confidence																																											.	.
Query Sequence		G	N	A	T	D	S	S	S	S	T	S	S	M	T	E	N	S	D	G	Q	K	Q	N	N	E	W	F	H	G	V	L	Q	R	Q	D	A	D	E	L	L	V	.	.	K	P	G	S	F	L	L	R	A	S	E	V	H	G	K	M	S	M	I	L	S	V	R	H	D	G	K	L	H	N	I	A	V	N	S	D	T
Query Conservation																																											.	.
Alig confidence																																											.	.														.
Template Conservation																																																										.
Template Sequence		A	Q	T	K	N	G	Q	G	W	V	P	S	N	Y	I	T	P	V	N	S	L	E	K	H	S	W	Y	H	G	P	V	S	R	N	A	A	E	Y	L	L	S	S	G	I	N	G	S	F	L	V	R	E	S	E	S	S	.	P	G	Q	R	S	I	S	L	R	Y	E	G	R	V	Y	H	Y	R	I	N	T	A	S
Template Known Secondary structure					S	S							G	G	G				S	S	S	G	G	G	S	T	T														G	G	G			T	T								S	S	S	.	T	T									T	T											T
Template Predicted Secondary structure																																																										.
Template SS confidence
		121	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.		.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.
		83	.	.	.	.	.	.		90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120										.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.
Predicted Secondary structure									.																																.	.	.	.	.	.	.	.	.
Query SS confidence									.																																.	.	.	.	.	.	.	.	.
Query Sequence		G	E	N	F	W	F	E	.	G	H	R	E	K	S	I	D	Q	L	V	Q	W	H	M	T	T	S	T	P	I	T	K	T	S	G	V	K	L	K	Y	.	.	.	.	.	.	.	.	.	P	I	G	K	A	D	W	I	I	S	H	E	N	V	I	F	I	K	K	L	G	E	G	A	F	G	E	V	S	L	A	E
Query Conservation									.																																.	.	.	.	.	.	.	.	.
Alig confidence									.																																.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		D	G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L	V	H	H	H	S	T	V	A	D	G	L	I	T	T	L	H	Y	P	A	P	K	R	N	K	P	T	V	Y	G	V	S	P	N	Y	D	K	W	E	M	E	R	T	D	I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E	G	V
Template Known Secondary structure		T	S				S	S	T	T	S		B	S	S									T	T			T	T	S	S	S										S					S	S	S		S	S	S	S			B			G	G	G							S	G	G	G	T	T	S	S
Template Predicted Secondary structure
Template SS confidence
		200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.
		153	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		C	E	I	G	G	R	K	V	E	T	A	V	K	T	M	R	C	Q	M	T	R	D	T	R	A	A	F	M	K	E	A	R	L	M	R	K	Y	S	H	P	H	I	V	R	I	I	G	K	I	I	V	K	H	L	P	K	V	G	L	A	V	D	A	H	P	L	M	I	V	M	E	M	C	P	H	G	S	L	L	S
Query Conservation
Alig confidence							.	.														.	.																									.	.	.	.	.	.	.	.	.	.	.
Template Conservation							.	.														.	.																									.	.	.	.	.	.	.	.	.	.	.
Template Sequence		W	K	K	Y	S	.	.	L	T	V	A	V	K	T	L	K	E	D	T	M	.	.	E	V	E	E	F	L	K	E	A	A	V	M	K	E	I	K	H	P	N	L	V	Q	L	L	.	.	.	.	.	.	.	.	.	.	.	G	V	C	T	R	E	P	P	F	Y	I	I	T	E	F	M	T	Y	G	N	L	L	D
Template Known Secondary structure			G	G	G	T	.	.										S	S	S	S	.	.																		T	T	B					.	.	.	.	.	.	.	.	.	.	.					S	S	S	S									T	T		B
Template Predicted Secondary structure							.	.														.	.																									.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		280	.	.	.	.			.	.	.	.	.	290	.	.	.	.	.	.	.			.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.												.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.
		233	.	.		.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.		.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310
Predicted Secondary structure					.																																																											.
Query SS confidence					.																																																											.
Query Sequence		F	L	R	.	K	N	K	G	K	T	T	L	S	E	R	L	R	F	C	I	E	S	A	D	G	L	A	Y	L	E	K	K	Q	C	L	H	R	D	I	A	A	R	N	C	L	L	S	I	T	D	Q	I	K	I	S	D	F	G	L	S	D	D	.	K	R	T	E	M	H	D	D	T	L	D	K	V	P	V	K	W
Query Conservation					.																																																											.
Alig confidence					.																																																											.
Template Conservation
Template Sequence		Y	L	R	E	C	N	R	Q	E	V	N	A	V	V	L	L	Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K	K	N	F	I	H	R	N	L	A	A	R	N	C	L	V	G	E	N	H	L	V	K	V	A	D	F	G	L	S	R	L	M	T	G	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W
Template Known Secondary structure						S		T	T	T	S																						T	T				S			S	G	G	G					G	G	G							T	T						T	T							T	T					G	G	G
Template Predicted Secondary structure
Template SS confidence
		345	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.
		311	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390
Predicted Secondary structure
Query SS confidence
Query Sequence		L	A	P	E	V	M	Q	D	K	L	Y	S	L	K	S	D	V	W	A	F	G	V	L	M	W	E	I	Y	A	D	G	A	D	P	Y	P	G	M	T	N	L	V	T	R	A	K	I	F	C	D	D	Y	R	M	T	F	P	E	T	T	P	P	T	I	S	E	I	A	L	K	Q	C	W	A	K	L	P	S	D	R
Query Conservation
Alig confidence																																																	.																				.
Template Conservation																																																	.																				.
Template Sequence		T	A	P	E	S	L	A	Y	N	K	F	S	I	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	G	I	D	L	S	Q	V	Y	E	L	L	.	E	K	D	Y	R	M	E	R	P	E	G	C	P	E	K	V	Y	E	L	.	M	R	A	C	W	Q	W	N	P	S	D	R
Template Known Secondary structure																														T	T	S			S	S	T	T			T	T	T						.		T	T							T	T									.					T		S	S	G	G	G	S
Template Predicted Secondary structure																																																	.																				.
Template SS confidence
		425	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.		.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490		.	.	.	.	.	.	.	.	.	500	.	.
		391	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	T	M	K	T	V	H	H	K	L	K	D	L	S	M	P	M	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	S	F	A	E	I	H	Q	A	F	E	T	M	F	Q	E	S	S
Template Known Secondary structure													T	S		S	S	S
Template Predicted Secondary structure
Template SS confidence
		503	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D