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Job DescriptionG5EE56
Confidence100.00%DateFri May 3 21:16:22 BST 2013
Rank81Aligned Residues240
% Identity26%Templatec3vw6B_
PDB info PDB header:transferase/transferase inhibitorChain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   254.....260.........270.........280.... .....290.........300.........310.........320.........330..
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Query Sequence  NWEIPRNQLHLKRKLGDGNFGEVWYGKWRGI. VEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFYI
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Template Sequence  EYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPE. . . . . QPLHEEIALHKHLKHKNIVQYLGSFSENGFIKI
Template Known Secondary structure 

B
TTSSB

SSSTTT


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TT


TTB

TT
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   672.......680.........690.........700.........710... ......720.........730.........740......
 
   333......340.........350... ......360.........370.........380.........390.........400.........410
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Query Sequence  ITEYMINGSLLQYLRTDGSTL. . GIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKL
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Template Sequence  FMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTY. . . SGVLKISDFGTSKRL
Template Known Secondary structure 

TT
BTT


TT
TT
S

SGGG
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   753......760.........770.........780.........790.........800.........810.... .....820.........
 
   411........420.........430........ .440.........450.........460....... ..470.........480......
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Query Sequence  MEEDIYEARTGAKFPIKWTAPEAATCGN. . FTVKSDVWSYGILLYEIMTKGQVPYPGMH. . NREVVEQVELGYRMPMPRG
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Template Sequence  TGT. . . . . . . . . . . . LQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMAT. GKPPFYELGEPQAAMFKVGMFKVHPEIPES
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GGG
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TTGGG
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   840.. .......850.........860.........870...... ...880.........890.........900......
 
   487..490.........500.........510.....
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Query Sequence  CPEQIYEEVLLKCWDKTPDRRPTFDTLYH
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Template Sequence  MSAEA. KAFILKCFEPDPDKRACANDLLV
Template Known Secondary structure  S
.T
S
TTTS

T
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   907..910. ........920.........930....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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