|   |
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | |
. | . | . | . | 290 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . |  |  |  |  |  |  |  |
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | Q | L | H | L | K | R | K | L | G | D | G | N | F | G | E | V | W | Y | G | K | W | R | G | I | V | . |
E | V | A | I | K | T | M | K | P | G | T | M | S | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
E | A | F | L | Q | E | A | Q | I | M | K | Q | C | D | H | P | N | L | V | K | L | Y | A | V | C | T | R | E | E | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   | . |   |
|
|
|
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | K | Y | S | T | M | S | P | L | G | S | G | A | F | G | F | V | W | T | A | V | D | K | E | K | N | K | E | V | V | V | K | F | I | K | K | E | K | V | L | E | D | C | W | I | E | D | P | K | L | G | K | V | T | L | E | I | A | I | L | S | R | V | E | H | A | N | I | I | K | V | L | D | I | F | E | N | Q | G | F |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
| S | S | S | S | S |
| S |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  | S | T | T | S |
| T | T | S |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| T | T | B |
|
|  |  |  |  |  |  |
| S | S |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
997 | . | . | 1000 | . | . | . | . | . | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020 | . | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . |
  |
  |   |
330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | Y | I | I | T | E | Y | M | I | N | G | S | L | L | Q | Y | L | R | T | D | G | S | T | L | G | I | Q | A | L | V | D | M | A | A | Q | I | A | N | G | M | M | Y | L | E | E | R | K | L | V | H | R | D | L | A | A | R | N | V | L | V | G | D | K | I | S | G | V | P | V | V | K | V | A | D | F | G | L | A | R | K |
Query Conservation |   |
  |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |
|
|   |   |   |   |   |
|   |
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
F | Q | L | V | M | E | K | H | G | S | G | L | D | L | F | A | F | I | D | R | H | P | R | L | D | E | P | L | A | S | Y | I | F | R | Q | L | V | S | A | V | G | Y | L | R | L | K | D | I | I | H | R | D | I | K | D | E | N | I | V | I | A | E | D | F | T | . |
. |
. |
. |
I | K | L | I | D | F | G | S | A | A | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |
|
| T | T | S |
| B |  |  |  |  |  |  | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
| S | G | G | G |  |  |  |
| T | T | S |
| . | . | . | . |  |  |  |
|
|
| T | T |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1077 | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140 | . | |
|
|
|
. | . | . | . | . | . | . | . | 1150 | . | . |
  |
  |   |
410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | |
. | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | M | E | E | D | I | Y | E | A | R | T | G | A | K | F | P | I | K | W | T | A | P | E | A | A | T | C | G | N | . |
F | T | V | K | S | D | V | W | S | Y | G | I | L | L | Y | E | I | M | T | K | G | Q | V | P | Y | P | G | M | H | N | R | E | V | V | E | Q | V | E | L | G | Y | R | M | P | M | P | R | G | C | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   | . |   |   |   |   |
|
|
|   |
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|
| . |
|   |   |
|
|   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
L | E | R | G | K | L | F | Y | T | F | C | G | T | I | . |
. |
. |
E | Y | C | A | P | E | V | L | M | G | N | P | Y | R | G | P | E | L | E | M | W | S | L | G | V | T | L | Y | T | L | V | F | . |
E | E | N | P | F | C | E | L | E | E | . |
. |
. |
. |
. |
. |
. |
T | V | E | A | A | I | H | P | P | Y | L | V | S |
Template Known Secondary structure |   |
|
| T | T |
|
| B |
| S |
|
| S |
| G | . | . | . | G | G |
|
|  |  |  |  | T | T |
|
| B |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S |
| S | S | G | G | G | . | . | . | . | . | . | . | G | T | T | T |
|
|
|
| S | S |
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1153 | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | |
|
|
. | . | . | 1170 | . | . | . | . | . | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | |
. | 1200 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 1210 | . | . | . | . | . | . | . | . | . | 1220 | . |
  |
  |   |
489 | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | Q | I | Y | E | E | V | L | L | K | C | W | D | K | T | P | D | R | R | P | T | F | D | T | L | Y | H |
Query Conservation |   |
  |   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |
Alig confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   | . |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
Template Sequence |   |
K | E | L | . |
M | S | L | V | S | G | L | L | Q | P | V | P | E | R | R | T | T | L | E | K | L | V | T |
Template Known Secondary structure |   |
 |  |  | . |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1222 | . | . | |
. | . | . | . | . | 1230 | . | . | . | . | . | . | . | . | . | 1240 | . | . | . | . | . | . | . |
  |