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Job DescriptionG5EE56
Confidence100.00%DateFri May 3 21:16:22 BST 2013
Rank239Aligned Residues251
% Identity36%Templatec3c1xA_
PDB info PDB header:transferaseChain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor
Resolution2.17 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   253......260. ........270.........280..... ....290........ .300.........310.........320....
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Query Sequence  QNWEIPRNQ. . LHLKRKLGDGNFGEVWYGKWRGIV. . . . EVAIKTMKPGTMS. . PEAFLQEAQIMKQCDHPNLVKLYAVC
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Template Sequence  QHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC
Template Known Secondary structure  TTTB

STT

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   1067..1070.........1080.........1090.........1100.........1110.........1120.........1130.........1140......
 
   325....330..... ....340.........350.........360.........370.........380.........390.........400...
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Query Sequence  TREEPFYIITE. YMINGSLLQYLRTDGSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVAD
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Template Sequence  LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKFLASKKFVHRDLAARNCMLDEKFT. . . . VKVAD
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   1147..1150.........1160.........1170.........1180.........1190.........1200.........1210....... ..1220..
 
   404.....410.........420.........430.........440.........450.........460.........470.........480...
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Query Sequence  FGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPM
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Template Sequence  FLPV. . . . . . . . . . . . . . . . . . . KWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQ
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   1223... ...1230.........1240.........1250.........1260.........1270.........1280...
 
   484.....490.........500.........510.........520.......
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Query Sequence  PRGCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYFVSTQPN
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Template Sequence  PEYCPDPL. YEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE
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   1305....1310.. .......1320.........1330.........1340.......
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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