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Job DescriptionG5EE56
Confidence100.00%DateFri May 3 21:16:22 BST 2013
Rank3Aligned Residues443
% Identity57%Templatec2h8hA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor
Resolution2.20 Å
Model Dimensions (Å)X:67.923 Y:79.666 Z:49.416

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   75....80.........90.........100.........110.........120.........130.........140.........150....
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Query Sequence  TLVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERLVLS
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Template Sequence  TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLN
Template Known Secondary structure 
SS
B


SSSB

B
TT

SSSSTTT

GGGTTSGGGSTTB

S

T
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   85....90.........100.........110.........120.........130.........140.........150.........160....
 
   155....160.........170.........180.........190.........200.........210.........220.........230....
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Query Sequence  SHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQGYFITTRRTFRSLQELVRYYSDVPDGLCCQLT
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Template Sequence  AENPRGTFLVRESETTKGAYCLSVSDFDN. AKGLNVKHYKIR. KLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLT
Template Known Secondary structure  TT

TT
SSSTT
T.TTB.
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S
TTSS

TTSSS


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   165....170.........180.........190... ......200..... ....210.........220.........230.........240..
 
   235....240.........250.........260.........270.........280.........290.........300.........310....
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Query Sequence  FPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDH
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Template Sequence  TVCPTSKPQTQGLAKD. . . AWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRH
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SSSSTT...
SB

GGG
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   243......250........ .260.........270.........280.........290.........300.........310.........
 
   315....320.........330.........340...... ...350.........360.........370.........380.........390...
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Query Sequence  PNLVKLYAVCTREEPFYIITEYMINGSLLQYL. RTDGSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKI
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Template Sequence  EKLVQLYAVVS. EEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENL
Template Known Secondary structure  TTB


.SSS



TTSTT

TT


S

SGGG
GGG
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   320.........330 .........340.........350.........360.........370.........380.........390........
 
   394.....400.........410.........420.........430.........440.........450.........460.........470...
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Query Sequence  SGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVE
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Template Sequence  V. . . . CKVADFGLARLI. EDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLD
Template Known Secondary structure 
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TTSTTT
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TT
STTS
GGGS




TTTT

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   399 400.........410. ........420.........430.........440.........450.........460.........470...
 
   474.....480.........490.........500.........510.........520.........530.
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Query Sequence  QVELGYRMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYFVSTQPNYAPP
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Template Sequence  QVERGYRMPCPPECPESL. HDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQ. . QP
Template Known Secondary structure  TT





TT

.T
SSGGGS

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   474.....480.........490. ........500.........510.........520...... ..
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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