|   |
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | |
|
. | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | N | W | E | I | P | R | N | Q | L | H | L | K | R | K | L | G | D | G | N | F | G | E | V | W | Y | G | K | W | R | G | . |
. |
. |
. |
. |
I | V | E | V | A | I | K | T | M | K | P | G | T | M | S | . |
. |
P | E | A | F | L | Q | E | A | Q | I | M | K | Q | C | D | H | P | N | L | V | K | L | Y | A | V | C | T |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |
Template Sequence |   |
D | P | T | V | F | H | K | R | Y | L | K | K | I | R | D | L | G | E | G | H | F | G | K | V | S | L | Y | C | Y | D | P | T | N | D | G | T | G | E | M | V | A | V | K | A | L | K | E | G | C | G | P | Q | L | R | S | G | W | Q | R | E | I | E | I | L | R | T | L | Y | H | E | H | I | V | K | Y | K | G | C | C | E |
Template Known Secondary structure |   |
| T | T | B |
|
| G | G | G |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |
| T | T |
|
| S | S |
|  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
884 | . | . | . | . | . | 890 | . | . | . | . | . | . | . | . | . | 900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | . | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . | . | 940 | . | . | . | . | . | . | . | . | . | 950 | . | . | . | . | . | . | . | . | . | 960 | . | . | . |
  |
  |   |
326 | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | E | E | P | F | Y | I | I | T | E | Y | M | I | N | G | S | L | L | Q | Y | L | R | T | D | G | S | T | L | G | I | Q | A | L | V | D | M | A | A | Q | I | A | N | G | M | M | Y | L | E | E | R | K | L | V | H | R | D | L | A | A | R | N | V | L | V | G | D | K | I | S | G | V | P | V | V | K | V | A | D | F | G |
Query Conservation |   |
  |   |   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |
|
|   |   |   |   |   |
|   |
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |
|   |
|
|
|
Template Sequence |   |
D | K | S | V | Q | L | V | M | E | Y | V | P | L | . |
G | S | L | R | D | Y | L | P | R | H | C | . |
. |
V | G | L | A | Q | L | L | L | F | A | Q | Q | I | C | E | G | M | A | Y | L | H | A | Q | H | Y | I | H | R | A | L | A | A | R | N | V | L | L | D | N | D | R | L | . |
. |
. |
. |
V | K | I | G | D | F | G |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
| T | T | . |  |  |  |  |  |  | G | G | G | S |
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
| S | G | G | G |  |  |  |
| G | G | G |
| . | . | . | . |  |  |  |
|
|
| T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
964 | . | . | . | . | . | 970 | . | . | . | . | . | . | |
. | . | . | 980 | . | . | . | . | . | . | . | |
|
. | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | . | . | . | . | . | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020 | . | . | . | . | . | . | . | . | . | |
|
|
|
1030 | . | . | . | . | . | . |
  |
  |   |
406 | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | |
. | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
| . |
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
Query Sequence |   |
L | A | R | K | L | M | E | E | D | I | Y | E | A | R | T | G | A | K | F | . |
P | I | K | W | T | A | P | E | A | A | T | C | G | N | F | T | V | K | S | D | V | W | S | Y | G | I | L | L | Y | E | I | M | T | K | G | Q | V | P | Y | P | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | H | N | R |
Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |
|
|
|
| . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | A | K | A | V | P | E | G | H | E | Y | Y | R | V | R | E | D | G | D | S | P | V | F | W | Y | A | P | E | C | L | K | E | C | K | F | Y | Y | A | S | D | V | W | S | F | G | V | T | L | Y | E | L | L | T | . |
Y | C | D | S | N | Q | S | P | H | T | K | F | T | E | L | I | G | H | T | Q | G | Q | M | T | V | L |
Template Known Secondary structure |   |
T |
|  |  |
|
| T | T |
| S |  |  |  |
|
|
|
| S | S | S |
| G | G | G |
|
|  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | T | T |
| T | T | S | S |  |  |  |  |  |  |  |  |  |
| S |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | |
. | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . |
  |
  |   |
470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | V | V | E | Q | V | E | L | G | Y | R | M | P | M | P | R | G | C | P | E | Q | I | Y | E | E | V | L | L | K | C | W | D | K | T | P | D | R | R | P | T | F | D | T | L | Y | H | F | F | D | D | Y | F | V | S | T | Q |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . |   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
R | L | T | E | L | L | E | R | G | E | R | L | P | R | P | D | R | C | P | C | E | I | . |
Y | H | L | M | K | N | C | W | E | T | E | A | S | F | R | P | T | F | Q | N | L | V | P | I | L | Q | T | A | Q | E | K | Y | Q |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T |
|
|
|
|
|
| T | T |
|
|  |  |  | . |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1119 | 1120 | . | . | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140 | |
. | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . |
  |