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Job DescriptionG5EE56
Confidence100.00%DateFri May 3 21:16:22 BST 2013
Rank275Aligned Residues257
% Identity19%Templatec2pvmA_
PDB info PDB header:transferaseChain: A: PDB Molecule:casein kinase ii subunit alpha; PDBTitle: structure-based design of pyrazolo[1,5-a][1,3,5]triazine2 derivatives as potent inhibitors of protein kinase ck2
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   257..260.........270.........280. ........290.........300.........310.........320......... 330...
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Query Sequence  IPRNQLHLKRKLGDGNFGEVWYGKW. RGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEP. . FYII
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Template Sequence  GEQDDYEVVRKVGRGKYSEVFEGINVNNNEKCIIKILK. . PVKKKKIKREIKILQNLGGPNIVKLLDIVRDQHSKTPSLI
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GGG
SSTTT


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   34.....40.........50.........60.........70. ........80.........90.........100.........110.
 
   334.....340.........350.........360.........370.........380.........390.........400.........410...
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Query Sequence  TEYMINGSLLQYLRTDGSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEE
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Template Sequence  FEYVNNTDFKVLY. . . . PTLTDYDIRYYIYELLKALDYCHSQGIMHRDVKPHNVMIDHELRK. . . LRLIDWGLAEFYHPG
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G....GG

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SGGGTTTT...


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   113......120..... ....130.........140.........150.........160.........170 .........180.....
 
   414.....420.........430...... ...440.........450.........460.........470....
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Query Sequence  DIYEARTGAKFPIKWTAPEAATC. GNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQ. . . . . . . . . . . . . . . . . .
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Template Sequence  KEYNVRVASRY. . . FKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTDGLNAYLNKYR
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   186...190...... ...200.........210.........220.........230.........240.........250.........260..
 
   475....480.........490.........500.........510..... ....520......
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Query Sequence  . . . . . . . . . . . . . . . . . . VELGYRMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLYH. . FFDDYFVSTQP
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Template Sequence  IELDPQLEALVGRHSRKPWLKFMNADNQHLVSPEA. IDFLDKLLRYDHQERLTALEAMTHPYFQQVRAAENS
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GGGG

TTTGGG

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   263......270.........280.........290....... ..300.........310.........320.........330...
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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