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Job DescriptionG5EE56
Confidence100.00%DateFri May 3 21:16:22 BST 2013
Rank4Aligned Residues438
% Identity42%Templatec1oplA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
Resolution3.42 Å
Model Dimensions (Å)X:72.113 Y:77.848 Z:56.408

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   72.......80.........90.........100.........110.........120.........130.........140.........150.
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Query Sequence  ERETLVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERL
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Template Sequence  DPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT. KNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYL
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TTSS
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STTB

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TT

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GGGSSSGGGSTT

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   81........90.........100.........110.........120... ......130.........140.........150.........
 
   152.......160.........170.........180.........190.........200.........210.........220.........230.
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Query Sequence  VLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQGYFITTRRTFRSLQELVRYYSDVPDGLCC
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Template Sequence  LSSG. . INGSFLVRESESSPGQRSISLR. . . . . . YEGRVYHYRINT. ASDGKLYVSSESRFNTLAELVHHHSTVADGLIT
Template Known Secondary structure  GGG
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   160... ......170.........180..... ....190....... ..200.........210.........220.........230
 
   232.......240.........250.........260.........270.........280... ......290.........300.........310
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Query Sequence  QLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRG. IVEVAIKTMKPGTMSPEAFLQEAQIMK
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Template Sequence  TLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMK
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SSS
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B

GGGSGGGTTSSGGGT

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   231........240.........250.........260.........270.........280.........290.........300.........310
 
   311........320.........330.........340.........350. ........360.........370.........380.........
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Query Sequence  QCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTDGS. TLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLV
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Template Sequence  EIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRNLAARNCLV
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   311........320.........330.........340.........350.........360.........370.........380.........390
 
   390.........400.........410.........420.........430.........440.........450.........460.........
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Query Sequence  GDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNR
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Template Sequence  GENHL. . . . VKVADFGLSRLM. TGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLS
Template Known Secondary structure 
GGG
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   391.... ....400....... ..410.........420.........430.........440.........450.........460.....
 
   470.........480.........490.........500.........510.........520.....
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Query Sequence  EVVEQVELGYRMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYFVSTQ
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Template Sequence  QVYELLEKDYRMERPEGCPEKV. YELMRACWQWNPSDRPSFAEIHQAFETMFQESS
Template Known Secondary structure  TTT





TT

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   466...470.........480....... ..490.........500.........510.........520
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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