Return to main results Retrieve Phyre Job Id

Job DescriptionG5EE56
Confidence100.00%DateFri May 3 21:16:22 BST 2013
Rank71Aligned Residues257
% Identity37%Templatec3v5qB_
PDB info PDB header:transferase/transferase inhibitorChain: B: PDB Molecule:nt-3 growth factor receptor; PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   255....260.........270... ......280..... ....290.... .....300.........310.........320.........330.
Predicted Secondary structure 









.



.

.












Query SS confidence 


















.











.








.




































Query Sequence  WEIPRNQLHLKRKLGDGNF. GEVWYGKWRGIV. EVAIKTMKP. GTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFY
Query Conservation    
          

 
 
.
 
         . 



    .          
   
  
 
 


   
         
Alig confidence 


















.











.








.
































..

Template Conservation    
          

 
 
 
 

          



 
             

  
  
 




         ..  
Template Sequence  QHIKRRDIVLKRELGFKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDP. . LI
Template Known Secondary structure 

GGG


S

SSSS

S




TTB




..
Template Predicted Secondary structure 






















..
Template SS confidence 















































































   531........540.........550.........560.........570.........580.........590.........600...... ..
 
   332.......340.........350.........360.........370.........380.........390.........400.........410.
Predicted Secondary structure 








































Query SS confidence 















































































Query Sequence  IITEYMINGSLLQYLRTDGSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLM
Query Conservation 

 
    


   
      
          


  
  

     
 


  



          

 




    
Alig confidence 






























































....












Template Conservation 

 
      
                                                    ....             
Template Sequence  MVFEYMKHGDLNKFLRAHGPELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLL. . . . VKIGDFGMDVYST
Template Known Secondary structure 

TTTT




TT


S

SGGG
GGG
....






SGG
Template Predicted Secondary structure 







































....






Template SS confidence 















































































   615....620.........630.........640.........650.........660.........670....... ..680.........690
 
   412.......420.........430.........440.........450.........460.........470.........480.........490.
Predicted Secondary structure 






































Query SS confidence 















































































Query Sequence  EEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPRGCPEQI
Query Conservation                  
 


          


 
 

 
 

 
 
  
            
        
       
Alig confidence 




......




































































Template Conservation       ......         
           





  





 
               
               
Template Sequence  DYYRT. . . . . . MLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEV
Template Known Secondary structure  G
B

......
B
GGG





TTTS

TTTTS
T





TT

Template Predicted Secondary structure 




......







































Template SS confidence 















































































   708.710.. .......720.........730.........740.........750.........760.........770.........780.
 
   492.......500.........510.........520....
Predicted Secondary structure 








Query SS confidence 
































Query Sequence  YEEVLLKCWDKTPDRRPTFDTLYHFFDDYFVST
Query Conservation     

  
    
  


   
   
       
Alig confidence  .































Template Conservation  .  

  

   
  


  


  
       
Template Sequence  . YDVMLGCWQREPQQRLNIKEIYKILHALGKAT
Template Known Secondary structure  .

SSGGGS

T
Template Predicted Secondary structure  .









Template SS confidence 
































   800.........810.........820.........830.
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions
Phyre2 is part of Genome3D