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Job DescriptionG5EE56
Confidence100.00%DateFri May 3 21:16:22 BST 2013
Rank78Aligned Residues253
% Identity34%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   253......260.........270.........280.........290.........300 .........310.........320.........
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Query Sequence  QNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPE. . . AFLQEAQIMKQCDHPNLVKLYAVCTREEP
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGKWHG. . DVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMG. YSTKPQ
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B

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   448.450.........460.........470........ .480.........490.........500.........510........ .520....
 
   330.........340.........350.........360.........370.........380.........390.........400.........
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Query Sequence  FYIITEYMINGSLLQYLRTDGSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARK
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Template Sequence  LAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLT. . . . VKIGDFGLATV
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SS
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SGGGTTT....


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   525....530.........540.........550.........560.........570.........580......... 590.........600
 
   410.........420.........430........ .440.........450.........460.........470 .........480..
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Query Sequence  LMEEDIYEARTGAKFPIKWTAPEAATCGN. . . FTVKSDVWSYGILLYEIMTKGQVPYPGMHNRE. VVEQVELGYRMP. . .
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Template Sequence  L. . . . . . . . . . . . SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSPDLS
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   613 ......620.........630.........640.........650. ........660.........670.........
 
   483......490.........500.........510.........520......
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Query Sequence  . MPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFDDYFVSTQP
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Template Sequence  KVRSNCPKAM. KRLMAECLKKKRDERPLFPQILASIELLARSLPK
Template Known Secondary structure  GS
TTS
.T
SSGGGS

T


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   680......... 690.........700.........710.........720...
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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