|   |
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | |
. | . | . | . | 290 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | |
|
. | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . |  |  |  |  |  |  |  |
|
|
|
|
|
|  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | N | Q | L | H | L | K | R | K | L | G | D | G | N | F | G | E | V | W | Y | G | K | W | R | G | I | V | . |
E | V | A | I | K | T | M | K | P | G | T | M | S | P | . |
. |
. |
. |
. |
. |
. |
E | A | F | L | Q | E | A | Q | I | M | K | Q | C | D | . |
. |
H | P | N | L | V | K | L | Y | A | V | C | T | R | E | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   | . |   |
|
|
|
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |
|   |   |
|   | . | . |
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |
|   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |
|
|   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | S | Q | Y | Q | V | G | P | L | L | G | S | G | G | F | G | S | V | Y | S | G | I | R | V | S | D | N | L | P | V | A | I | K | H | V | E | K | D | R | I | S | D | W | G | E | L | P | N | G | T | R | V | P | M | E | V | V | L | L | K | K | V | S | S | G | F | S | G | V | I | R | L | L | D | W | F | E | R | P | D |
Template Known Secondary structure |   |
T | T | T |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  | G | G | G |
|
|
|  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S |
| S | B |
|
|  |  |  |  |  |  |
| S | S |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
35 | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . |
  |
  |   |
329 | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | F | Y | I | I | T | E | Y | M | I | N | G | S | L | L | Q | Y | L | R | T | D | G | S | T | L | G | I | Q | A | L | V | D | M | A | A | Q | I | A | N | G | M | M | Y | L | E | E | R | K | L | V | H | R | D | L | A | A | R | N | V | L | V | G | D | K | I | S | G | V | P | V | V | K | V | A | D | F | G | L | A | R |
Query Conservation |   |
  |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |
|
|   |   |   |   |   |
|   |
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |
|
|   |   |   |   |   | . | . | . |   |   |   |   |   |
|   |
|
|
|   |   |   |
Template Sequence |   |
S | F | V | L | I | L | E | R | P | E | P | V | Q | D | L | F | D | F | I | T | E | R | G | A | L | Q | E | E | L | A | R | S | F | F | W | Q | V | L | E | A | V | R | H | C | H | N | C | G | V | L | H | R | D | I | K | D | E | N | I | L | I | D | L | N | . |
. |
. |
R | G | E | L | K | L | I | D | F | G | S | G | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
| S | G | G | G |  |  |  |  | T | T | . | . | . | T | T |  |  |  |  |
|
|
| T | T |
|  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
115 | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | |
|
|
. | 180 | . | . | . | . | . | . | . | . | . | 190 | . |
  |
  |   |
409 | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | |
. | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | L | M | E | E | D | I | Y | E | A | R | T | G | A | K | F | P | I | K | W | T | A | P | E | A | A | T | C | G | N | . |
F | T | V | K | S | D | V | W | S | Y | G | I | L | L | Y | E | I | M | T | K | G | Q | V | P | Y | P | G | M | H | N | R | E | V | V | E | Q | V | E | L | G | Y | R | M | P | M | P | R | G | C |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   | . |   |   |   |   |
|
|
|   |
|   |
|
|   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|
|
|
|
| . |
|   |   |
|
|   |   |   | . | . | . | . | . | . |   |   |
|   |   |   |   | . |   |   |   |   |   |   |   |
Template Sequence |   |
L | L | K | D | T | V | Y | T | D | F | D | . |
. |
. |
. |
G | T | R | V | Y | S | P | P | E | W | I | R | Y | H | R | Y | H | G | R | S | A | A | V | W | S | L | G | I | L | L | Y | D | M | V | C | . |
G | D | I | P | F | E | H | D | . |
. |
. |
. |
. |
. |
E | E | I | I | R | G | Q | . |
V | F | F | R | Q | R | V |
Template Known Secondary structure |   |
 |
|
| S | S |
| B |
|
|
|
| . | . | . | . | S |
| G | G | G | S |
|  |  |  |  |  |  | S |
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S |
|
| S |  | . | . | . | . | . | . |  |  |  |  |  |
|
| . |
|
|
| S | S |
|
|
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|  | . | . | . | . | . | . |  |  |  |  |  |
|
| . |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
192 | . | . | . | . | . | . | . | 200 | . | . | |
|
|
|
. | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | |
. | . | 240 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 250 | . | . | |
. | . | . | . | . | . | . |
  |
  |   |
488 | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | E | Q | I | Y | E | E | V | L | L | K | C | W | D | K | T | P | D | R | R | P | T | F | D | T | L | Y | H |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   | . |   |   |
|
|   |   |   |
|   |   |   |
|   |   |
|
|
|   |   |
|
|
|   |
Template Sequence |   |
S | S | E | C | . |
Q | H | L | I | R | W | C | L | A | L | R | P | S | D | R | P | T | F | E | E | I | Q | N |
Template Known Secondary structure |   |
|  |  |  | . |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|  |  |  | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
260 | . | . | . | |
. | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . |
  |