Job Description P03949 Confidence 100.00% Date Fri May 3 21:46:51 BST 2013 Rank 160 Aligned Residues 256 % Identity 34% Template c4e1zA_ PDB info PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structure of mouse tyk-2 complexed to a 3-aminoindazole inhibitor Resolution 2.50 Å

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		305	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.					.	.	.	.	.	.	.	340	.	.	.			.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.
Predicted Secondary structure																														.	.	.	.												.	.
Query SS confidence																														.	.	.	.												.	.
Query Sequence		E	L	D	R	S	E	I	I	M	H	N	K	L	G	G	G	Q	Y	G	D	V	Y	E	G	Y	W	K	R	.	.	.	.	H	D	C	T	I	A	V	K	A	L	K	.	.	E	D	A	M	P	L	H	E	F	L	A	E	A	A	I	M	K	D	L	H	H	K	N	L	V	R	L	L	G	V	C	T	H	E	A
Query Conservation																														.	.	.	.												.	.
Alig confidence																														.	.	.	.												.	.
Template Conservation
Template Sequence		V	F	H	K	R	Y	L	K	K	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	E	G	C	G	P	Q	L	R	S	G	W	Q	R	E	I	E	I	L	R	T	L	Y	H	E	H	I	V	K	Y	K	G	C	C	E	D	K	S
Template Known Secondary structure		B			G	G	G											S	S										T	T			S	S											T	T																						T	T	B
Template Predicted Secondary structure
Template SS confidence
		887	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.
		379	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	F	Y	I	I	T	E	F	M	C	N	G	N	L	L	E	Y	L	R	R	T	D	K	S	L	L	P	P	I	I	L	V	Q	M	A	S	Q	I	A	S	G	M	S	Y	L	E	A	R	H	F	I	H	R	D	L	A	A	R	N	C	L	V	S	E	H	N	I	V	K	I	A	D	F	G	L	A	R	F	M	K
Query Conservation
Alig confidence											.													.	.	.
Template Conservation											.													.	.	.
Template Sequence		V	Q	L	V	M	E	Y	V	P	.	L	G	S	L	R	D	Y	L	P	R	H	C	.	.	.	V	G	L	A	Q	L	L	L	F	A	Q	Q	I	C	E	G	M	A	Y	L	H	A	Q	H	Y	I	H	R	A	L	A	A	R	N	V	L	L	D	N	D	R	L	V	K	I	G	D	F	G	L	A	K	A	V	P
Template Known Secondary structure										T	.	T							G	G	G	S		.	.	.																							T	T				S			S	G	G	G					G	G	G								T	T
Template Predicted Secondary structure											.													.	.	.
Template SS confidence
		970	.	.	.	.	.	.	.	.		.	980	.	.	.	.	.	.	.	.	.	990				.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.
				459	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.																.	.	.	.	.	.	.	.	520	.
Predicted Secondary structure		.	.																																																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.																																																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	E	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	G	L	A	F	N	T	F	S	S	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	A	P	Y	P	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	V	E	L	S	N	V	Y	G	L	L
Query Conservation		.	.																																																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.																																														.								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																	.
Template Sequence		E	G	H	E	Y	Y	R	V	R	E	D	G	D	S	P	V	F	W	Y	A	P	E	C	L	K	E	C	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	T	.	Y	C	D	S	N	Q	S	P	H	T	K	F	T	E	L	I	G	H	T	Q	G	Q	M	T	V	L	R	L	T	E	L	L
Template Known Secondary structure		T	T		S								S	S	S		G	G	G								S																					T	.	T	T		T	T	S	S											S
Template Predicted Secondary structure																																																	.
Template SS confidence
		1046	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.		.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.
		522	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	N	G	F	R	M	D	G	P	Q	G	C	P	P	S	V	Y	R	L	M	L	Q	C	W	N	W	S	P	S	D	R	P	R	F	R	D	I	H	F	N	L	E	N	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	R	G	E	R	L	P	R	P	D	R	C	P	C	E	I	Y	H	L	M	K	N	C	W	E	T	E	A	S	F	R	P	T	F	Q	N	L	V	P	I	L	Q	T	A
Template Known Secondary structure				T							T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1125	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D