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Job DescriptionP03949
Confidence100.00%DateFri May 3 21:46:51 BST 2013
Rank226Aligned Residues251
% Identity27%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   309310.........320.........330.........340.........350.........360.........370... ......380....
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Query Sequence  SEIIMHNKLGGGQYGDVYEGYWKRHDCTIAVKALKEDAMPLHEFLAEAAIMKDLHHKNLVRLLGV. . . . CTHEAPFYIIT
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Template Sequence  RDITLLECVGKGRYGEVWRGSW. . QGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLIT
Template Known Secondary structure  TTTT..TT
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   206...210.........220....... ..230.........240.........250.........260.........270.........280...
 
   385....390.........400.........410.........420........ .430.........440.........450......
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Query Sequence  EFMCNGNLLEYLRRTDKSLLPPIILVQMASQIASGMSYLEARHF. . . . . . . . IHRDLAARNCLVSEHNIVKIADFGLARF
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Template Sequence  HYHEMGSLYDYLQLTT. . . LDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
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TT
B

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SGGG
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   284.....290......... 300.........310.........320.........330.........340.........350.........360
 
   457. .460.........470.........480.... .....490.........500.........510....
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Query Sequence  MK. . . EDTYTAHAGAKFPIKWTAPEGLAFNT. . . . . . FSSKSDVWAFGVLLWEIATYGMAPYPGVEL. . . . . . . . . . . . .
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Template Sequence  HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPNDP
Template Known Secondary structure  TTTT








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   361........370.........380.........390.........400.........410...... ...420.........430.........
 
   515....520.........530.. .......540.........550.........560.....
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Query Sequence  . . SNVYGLLENGFRMDGPQG. . . . . . CPPSVYRLMLQCWNWSPSDRPRFRDIHFNLENL
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Template Sequence  SFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
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   440.........450.........460.........470.........480.........490........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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