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Job DescriptionP03949
Confidence100.00%DateFri May 3 21:46:51 BST 2013
Rank101Aligned Residues247
% Identity34%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   302.......310.........320.........330.........340... ......350.........360.........370........
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Query Sequence  DEWELDRSEIIMHNKLGGGQYGDVYEGYWKRHDCTIAVKALK. . . EDAMPLHEFLAEAAIMKDLHHKNLVRLLGVCTHEA
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD. . . VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYST. KP
Template Known Secondary structure 


B

TT

TTSSS...

SSS

TT


TTB


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   448.450.........460.........470......... 480.........490.........500.........510.........520. ..
 
   379380.........390.........400.........410.........420.........430.........440.........450........
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Query Sequence  PFYIITEFMCNGNLLEYLRRTDKSLLPPIILVQMASQIASGMSYLEARHFIHRDLAARNCLVSEHNIVKIADFGLARFMK
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Template Sequence  QLAIVTQWCEGSSLYHHLHIIETK. FEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVL.
Template Known Secondary structure  S


SS
BTS


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TT
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S

SGGGTTT


TT
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   524.....530.........540....... ..550.........560.........570.........580.........590.........600.
 
   459460.........470.........480.... .....490.........500.........510...... ...520........ .530
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Query Sequence  EDTYTAHAGAKFPIKWTAPEGLAFNT. . . FSSKSDVWAFGVLLWEIATYGMAPYPGVELSN. VYGLLENGFRMD. . . . GP
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Template Sequence  . . . . . . . . . . SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSPDLSKVR
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TT

TT
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S.SS
TTTT


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   614.....620.........630.........640.........650. ........660.........670.........680..
 
   531........540.........550.........560.....
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Query Sequence  QGCPPSVYRLMLQCWNWSPSDRPRFRDIHFNLENL
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Template Sequence  SNCPKAMKRLMAECLKKKRDERPLFPQILASIELL
Template Known Secondary structure  TTS
T
SSGGGS

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   683......690.........700.........710.......
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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