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Job DescriptionP03949
Confidence100.00%DateFri May 3 21:46:51 BST 2013
Rank119Aligned Residues264
% Identity21%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   308.310.........320.........330.........340... ......350.........360.........370.........380...
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Query Sequence  RSEIIMHNKLGGGQYGDVYEGYWKRHDCTIAVKALK. . . . EDAMPLHEFLAEAAIMKDLHHKNLVRLLGVCTHEAPFYII
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Template Sequence  PEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFG
Template Known Secondary structure  GGG
SS
TTT

TT
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   7980.........90.........100.........110.........120.........130.........140.........150........
 
   384.....390.........400.........410.........420.........430.........440.........450.........460...
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Query Sequence  TEFMCNGNLLEYLRRTDKSLLPPIILVQMASQIASGMSYLEARHFIHRDLAARNCLVSEHNIVKIADFGLARFMKEDTYT
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Template Sequence  LSYAKNGELLKYIRKIGS. . FDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL. . . . . .
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TT
BSSS..

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   159160.........170...... ...180.........190.........200.........210.........220.........230
 
   464.....470.........480.........490.........500.........510.........520.........530.........540...
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Query Sequence  AHAGAKFPIKWTAPEGLAFNTFSSKSDVWAFGVLLWEIATYGMAPYPGVELSNVYGLLENGFRMDGPQGCPPSVYRLMLQ
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Template Sequence  . . . . FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVA. GLPPFRAGNEYLIFQKIIKLE. YDFPEKFFPKARDLVEK
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GGG

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   242.......250.........260.........270....... ..280.........290........ .300.........310.....
 
   544.....550.........560.........570.........580.....
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Query Sequence  CWNWSPSDRPRFRDIHFNLENLISSNSLNDEVQKQLKKNNDK
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Template Sequence  LLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPK
Template Known Secondary structure  TS
SSTTSSTTSGGGTTSGGGTT

GGGGGGS



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   316...320.........330.........340.........350.......
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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