Job Description P03949 Confidence 100.00% Date Fri May 3 21:46:51 BST 2013 Rank 4 Aligned Residues 430 % Identity 44% Template c2h8hA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor Resolution 2.20 Å Model Dimensions (Å) X:74.960 Y:76.354 Z:48.423

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		120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	V	A	L	Y	D	F	H	G	V	G	E	E	Q	L	S	L	R	K	G	D	Q	V	R	I	L	G	Y	N	K	N	N	E	W	C	E	A	R	L	Y	S	T	R	K	N	D	A	S	N	Q	R	R	L	G	E	I	G	W	V	P	S	N	F	I	A	P	Y	N	S	L	D	K	Y	T	W	Y	H	G	K	I
Query Conservation
Alig confidence																													.															.	.	.	.	.	.	.	.	.	.	.
Template Conservation																													.															.	.	.	.	.	.	.	.	.	.	.
Template Sequence		F	V	A	L	Y	D	Y	E	S	R	T	E	T	D	L	S	F	K	K	G	E	R	L	Q	I	V	N	.	N	T	E	G	D	W	W	L	A	H	S	L	S	T	.	.	.	.	.	.	.	.	.	.	.	G	Q	T	G	Y	I	P	S	N	Y	V	A	P	S	D	S	I	Q	A	E	E	W	Y	F	G	K	I
Template Known Secondary structure					S	S		B				S	S	S	B			B		T	T								.		S	S	S	S							T	T	T	.	.	.	.	.	.	.	.	.	.	.								G	G	G				T	T	S	G	G	G	S	T	T	B			S
Template Predicted Secondary structure																													.															.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		86	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.		.	.	.	.	.	.	.	120	.	.	.	.	.	.												.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.
		200	.	.	.	.	.	.	.	.	.	210	.			.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.						.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.
Predicted Secondary structure														.	.																								.	.	.	.	.
Query SS confidence														.	.																								.	.	.	.	.
Query Sequence		S	R	S	D	S	E	A	I	L	G	S	G	.	.	I	T	G	S	F	L	V	R	E	S	E	T	S	I	G	Q	Y	T	I	S	V	R	H	.	.	.	.	.	D	G	R	V	F	H	Y	R	I	N	V	D	N	T	E	K	M	F	I	T	Q	E	V	K	F	R	T	L	G	E	L	V	H	H	H	S	V	H
Query Conservation														.	.																								.	.	.	.	.
Alig confidence														.	.																								.	.	.	.	.
Template Conservation
Template Sequence		T	R	R	E	S	E	R	L	L	L	N	A	E	N	P	R	G	T	F	L	V	R	E	S	E	T	T	K	G	A	Y	C	L	S	V	S	D	F	D	N	A	K	G	L	N	V	K	H	Y	K	I	R	K	L	D	S	G	G	F	Y	I	T	S	R	T	Q	F	N	S	L	Q	Q	L	V	A	Y	Y	S	K	H
Template Known Secondary structure											T		T	T			T	T								S	S	S	T	T											T	T	T										B		.			S						T	T				S	S
Template Predicted Secondary structure
Template SS confidence
		154	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.
		273	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	D	G	L	I	C	L	L	M	Y	P	A	S	K	K	D	K	G	R	G	L	F	S	L	S	P	N	A	P	D	E	W	E	L	D	R	S	E	I	I	M	H	N	K	L	G	G	G	Q	Y	G	D	V	Y	E	G	Y	W	K	R	H	D	C	T	I	A	V	K	A	L	K	E	D	A	M	P	L	H	E	F
Query Conservation
Alig confidence																				.	.	.	.	.																																							.
Template Conservation																				.	.	.	.	.																																							.
Template Sequence		A	D	G	L	C	H	R	L	T	T	V	C	P	T	S	K	P	Q	.	.	.	.	.	T	Q	G	L	A	K	D	A	W	E	I	P	R	E	S	L	R	L	E	V	K	L	G	Q	G	C	F	G	E	V	W	M	G	T	W	N	G	T	.	T	R	V	A	I	K	T	L	K	P	G	T	M	S	P	E	A	F
Template Known Secondary structure			T	T	S	S	S													.	.	.	.	.		S	S	S	S	T	T		S	B			G	G	G											S	S									T	T	T	.										T	T	S	S
Template Predicted Secondary structure																				.	.	.	.	.																																							.
Template SS confidence
		234	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.						.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.		290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.
		353	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	A	E	A	A	I	M	K	D	L	H	H	K	N	L	V	R	L	L	G	V	C	T	H	E	A	P	F	Y	I	I	T	E	F	M	C	N	G	N	L	L	E	Y	L	R	R	T	D	K	S	L	L	P	P	I	I	L	V	Q	M	A	S	Q	I	A	S	G	M	S	Y	L	E	A	R	H	F	I	H	R	D
Query Conservation
Alig confidence																									.
Template Conservation																									.
Template Sequence		L	Q	E	A	Q	V	M	K	K	L	R	H	E	K	L	V	Q	L	Y	A	V	V	S	.	E	E	P	I	Y	I	V	T	E	Y	M	S	K	G	S	L	L	D	F	L	K	G	E	T	G	K	Y	L	R	L	P	Q	L	V	D	M	A	A	Q	I	A	S	G	M	A	Y	V	E	R	M	N	Y	V	H	R	D
Template Known Secondary structure														T	T	B									.	S	S	S									T	T								S					T	T																							T	T				S
Template Predicted Secondary structure																									.
Template SS confidence
		308	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330		.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.
		433	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	A	A	R	N	C	L	V	S	E	H	N	I	V	K	I	A	D	F	G	L	A	R	F	M	K	E	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	G	L	A	F	N	T	F	S	S	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	A	P	Y	P	G	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	R	A	A	N	I	L	V	G	E	N	L	V	C	K	V	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	Q	G	A	K	F	P	I	K	W	T	A	P	E	A	A	L	Y	G	R	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	L	T	T	K	G	R	V	P	Y	P	G	M
Template Known Secondary structure			S	G	G	G					G	G	G							T	T	S	T	T	T								T	T		S	T	T	S		G	G	G	S																											T	T	T	T			S	S	T	T
Template Predicted Secondary structure
Template SS confidence
		387	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.
		513	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	L	S	N	V	Y	G	L	L	E	N	G	F	R	M	D	G	P	Q	G	C	P	P	S	V	Y	R	L	M	L	Q	C	W	N	W	S	P	S	D	R	P	R	F	R	D	I	H	F	N	L	E	N	L	I	S	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	N	R	E	V	L	D	Q	V	E	R	G	Y	R	M	P	C	P	P	E	C	P	E	S	L	H	D	L	M	C	Q	C	W	R	K	E	P	E	E	R	P	T	F	E	Y	L	Q	A	F	L	E	D	Y	F	T	S
Template Known Secondary structure												T	T							T	T													T		S	S	G	G	G	S												T	S	S
Template Predicted Secondary structure
Template SS confidence
		467	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.