Job Description P03949 Confidence 100.00% Date Fri May 3 21:46:51 BST 2013 Rank 1 Aligned Residues 458 % Identity 60% Template c2fo0A_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase Resolution 2.27 Å Model Dimensions (Å) X:66.737 Y:72.409 Z:46.644

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		107	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	T	V	S	S	S	S	S	S	S	A	P	L	F	V	A	L	Y	D	F	H	G	V	G	E	E	Q	L	S	L	R	K	G	D	Q	V	R	I	L	G	Y	N	K	N	N	E	W	C	E	A	R	L	Y	S	T	R	K	N	D	A	S	N	Q	R	R	L	G	E	I	G	W	V	P	S	N	F	I	A	P	Y
Query Conservation
Alig confidence																																																								.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																								.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		N	L	L	A	G	P	S	E	N	D	P	N	L	F	V	A	L	Y	D	F	V	A	S	G	D	N	T	L	S	I	T	K	G	E	K	L	R	V	L	G	Y	N	H	N	G	E	W	C	E	A	Q	T	K	N	.	.	.	.	.	.	.	.	.	.	.	.	.	G	Q	G	W	V	P	S	N	Y	I	T	P	V
Template Known Secondary structure		T	T	T			G	G	G	S		T	T					S	S		B				S	T	T	B			B		T	T										T	T	S	S							T	T	.	.	.	.	.	.	.	.	.	.	.	.	.							G	G	G				T
Template Predicted Secondary structure																																																								.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		72	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.														.	.	.	.	130	.	.	.	.	.	.	.	.
		187	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	S	L	D	K	Y	T	W	Y	H	G	K	I	S	R	S	D	S	E	A	I	L	G	S	G	I	T	G	S	F	L	V	R	E	S	E	T	S	I	G	Q	Y	T	I	S	V	R	H	D	G	R	V	F	H	Y	R	I	N	V	D	N	T	E	K	M	F	I	T	Q	E	V	K	F	R	T	L	G	E	L	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		N	S	L	E	K	H	S	W	Y	H	G	P	V	S	R	N	A	A	E	Y	L	L	S	S	G	I	N	G	S	F	L	V	R	E	S	E	S	S	P	G	Q	R	S	I	S	L	R	Y	E	G	R	V	Y	H	Y	R	I	N	T	A	S	D	G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L	V
Template Known Secondary structure		T	S	G	G	G	S	T	T														T	S	S	S		T	T								S	S	S	T	T									T	T											T	T	S				S	S	T	T			B	S	S
Template Predicted Secondary structure
Template SS confidence
		139	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.
		267	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	H	H	S	V	H	A	D	G	L	I	C	L	L	M	Y	P	A	S	K	K	D	K	G	R	G	L	F	S	L	S	P	N	A	P	D	E	W	E	L	D	R	S	E	I	I	M	H	N	K	L	G	G	G	Q	Y	G	D	V	Y	E	G	Y	W	K	R	H	D	C	T	I	A	V	K	A	L	K	E	D	A
Query Conservation
Alig confidence																																			.	.
Template Conservation																																			.	.
Template Sequence		H	H	H	S	T	V	A	D	G	L	I	T	T	L	H	Y	P	A	P	K	R	N	K	P	T	V	Y	G	V	S	P	N	Y	.	.	D	K	W	E	M	E	R	T	D	I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E	G	V	W	K	K	Y	S	L	T	V	A	V	K	T	L	K	E	D	T
Template Known Secondary structure									T	T	S	S	S															S	S	S		S	S	T	.	.	T			B			G	G	G							S	G	G	G	T	T	S	S							G	G	G	T										T	T	S
Template Predicted Secondary structure																																			.	.
Template SS confidence
		219	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.			.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.
		347	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	P	L	H	E	F	L	A	E	A	A	I	M	K	D	L	H	H	K	N	L	V	R	L	L	G	V	C	T	H	E	A	P	F	Y	I	I	T	E	F	M	C	N	G	N	L	L	E	Y	L	R	R	T	D	K	S	L	L	P	P	I	I	L	V	Q	M	A	S	Q	I	A	S	G	M	S	Y	L	E	A	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	E	V	E	E	F	L	K	E	A	A	V	M	K	E	I	K	H	P	N	L	V	Q	L	L	G	V	C	T	R	E	P	P	F	Y	I	I	T	E	F	M	T	Y	G	N	L	L	D	Y	L	R	E	C	N	R	Q	E	V	N	A	V	V	L	L	Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K	K
Template Known Secondary structure																				T	T	B									S	S	S	S									T	T		B								S		T	T	T	S																						T
Template Predicted Secondary structure
Template SS confidence
		297	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.
		427	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	F	I	H	R	D	L	A	A	R	N	C	L	V	S	E	H	N	I	V	K	I	A	D	F	G	L	A	R	F	M	K	E	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	G	L	A	F	N	T	F	S	S	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M
Query Conservation
Alig confidence
Template Conservation
Template Sequence		N	F	I	H	R	N	L	A	A	R	N	C	L	V	G	E	N	H	L	V	K	V	A	D	F	G	L	S	R	L	M	T	G	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	S	L	A	Y	N	K	F	S	I	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M
Template Known Secondary structure		T				S			S	G	G	G					G	G	G							T	T						S	S							T	T					G	G	G																													T	T	S
Template Predicted Secondary structure
Template SS confidence
		377	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.
		507	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	P	Y	P	G	V	E	L	S	N	V	Y	G	L	L	E	N	G	F	R	M	D	G	P	Q	G	C	P	P	S	V	Y	R	L	M	L	Q	C	W	N	W	S	P	S	D	R	P	R	F	R	D	I	H	F	N	L	E	N	L	I	S	S	N	S	L	N	D	E	V	Q	K	Q	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	P	Y	P	G	I	D	L	S	Q	V	Y	E	L	L	E	K	D	Y	R	M	E	R	P	E	G	C	P	E	K	V	Y	E	L	M	R	A	C	W	Q	W	N	P	S	D	R	P	S	F	A	E	I	H	Q	A	F	E	T	M	F	Q	E	S	S	I	S	D	E	V	E	K	E	L
Template Known Secondary structure			S	S	T	T												T	T							T	T													T		S	S	G	G	G	S												T	S	S	S	S	S
Template Predicted Secondary structure
Template SS confidence
		457	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.