Job Description P03949 Confidence 100.00% Date Fri May 3 21:46:51 BST 2013 Rank 6 Aligned Residues 424 % Identity 43% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å Model Dimensions (Å) X:85.096 Y:72.999 Z:51.506

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		119	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	F	V	A	L	Y	D	F	H	G	V	G	E	E	Q	L	S	L	R	K	G	D	Q	V	R	I	L	G	Y	N	K	N	N	E	W	C	E	A	R	L	Y	S	T	R	K	N	D	A	S	N	Q	R	R	L	G	E	I	G	W	V	P	S	N	F	I	A	P	Y	N	S	L	D	K	Y	T	W	Y	H	G	K
Query Conservation
Alig confidence																													.	.															.	.	.	.	.	.	.	.	.	.	.
Template Conservation																													.	.															.	.	.	.	.	.	.	.	.	.	.
Template Sequence		I	V	V	A	L	Y	D	Y	E	A	I	H	H	E	D	L	S	F	Q	K	G	D	Q	M	V	V	L	.	.	E	E	S	G	E	W	W	K	A	R	S	L	A	T	.	.	.	.	.	.	.	.	.	.	.	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	D	S	L	E	T	E	E	W	F	F	K	G
Template Known Secondary structure						S	S		B				S	S	S	B			B		T	T							.	.				T	T							T	T	T	.	.	.	.	.	.	.	.	.	.	.								G	G	G				T	T	S	G	G	G	S	T	T			T	T
Template Predicted Secondary structure																													.	.															.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.			.	.	90	.	.	.	.	.	.	.	.	.	100	.												.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.
		199	200	.	.	.	.	.	.	.	.			.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.						.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.
Predicted Secondary structure												.	.																										.	.	.	.	.
Query SS confidence												.	.																										.	.	.	.	.
Query Sequence		I	S	R	S	D	S	E	A	I	L	.	.	G	S	G	I	T	G	S	F	L	V	R	E	S	E	T	S	I	G	Q	Y	T	I	S	V	R	.	.	.	.	.	H	D	G	R	V	F	H	Y	R	I	N	V	D	N	T	E	K	M	F	I	T	Q	E	V	K	F	R	T	L	G	E	L	V	H	H	H	S	V
Query Conservation												.	.																										.	.	.	.	.
Alig confidence												.	.																										.	.	.	.	.
Template Conservation
Template Sequence		I	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y	S	L	S	V	R	D	Y	D	P	R	Q	G	D	T	V	K	H	Y	K	I	R	T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K
Template Known Secondary structure												T	S	T	T			T	T								S	S	S	T	T											T	T	T										B			S	T	T				S	S	T	T	S			S	S								T	T	S
Template Predicted Secondary structure
Template SS confidence
		128	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.
		272	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	A	D	G	L	I	C	L	L	M	Y	P	A	S	K	K	D	K	G	R	G	L	F	S	L	S	P	N	A	P	D	E	W	E	L	D	R	S	E	I	I	M	H	N	K	L	G	G	G	Q	Y	G	D	V	Y	E	G	Y	W	K	R	H	D	C	T	I	A	V	K	A	L	K	E	D	A	M	P	L	H	E
Query Conservation
Alig confidence																			.	.	.	.	.	.																																								.
Template Conservation																			.	.	.	.	.	.																																								.
Template Sequence		G	N	D	G	L	C	Q	K	L	S	V	P	C	M	S	S	K	.	.	.	.	.	.	P	Q	K	P	W	E	K	D	A	W	E	I	P	R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	K	H	.	T	K	V	A	V	K	T	M	K	P	G	S	M	S	V	E	A
Template Known Secondary structure		S		S	S		S	S				S	B						.	.	.	.	.	.							T	T		S	B			G	G	G											T	T									T	T	T	.												S	S
Template Predicted Secondary structure																			.	.	.	.	.	.																																								.
Template SS confidence
		208	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.							.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.		.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
		352	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	L	A	E	A	A	I	M	K	D	L	H	H	K	N	L	V	R	L	L	G	V	C	T	H	E	A	P	F	Y	I	I	T	E	F	M	C	N	G	N	L	L	E	Y	L	R	R	T	D	K	S	L	L	P	P	I	I	L	V	Q	M	A	S	Q	I	A	S	G	M	S	Y	L	E	A	R	H	F	I	H	R
Query Conservation
Alig confidence																									.
Template Conservation																									.
Template Sequence		F	L	A	E	A	N	V	M	K	T	L	Q	H	D	K	L	V	K	L	H	A	V	V	.	T	K	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R	N	Y	I	H	R
Template Known Secondary structure											T				T	T	B								.		S	S	S									T	T		B							S	T	T	G	G	G																							T	T				S
Template Predicted Secondary structure																									.
Template SS confidence
		281	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.		.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.
		432	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	L	A	A	R	N	C	L	V	S	E	H	N	I	V	K	I	A	D	F	G	L	A	R	F	M	K	E	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	G	L	A	F	N	T	F	S	S	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	A	P	Y	P	G
Query Conservation
Alig confidence																										.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																										.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		D	L	R	A	A	N	I	L	V	S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	.	.	.	.	.	.	.	.	.	.	.	.	.	V	I	P	I	K	W	T	A	P	E	A	I	N	F	G	S	F	T	I	K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G
Template Known Secondary structure				S	G	G	G					T	T								T	T	G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	T			G	G	G	S																												T	T	T			S	S	T	T
Template Predicted Secondary structure																										.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.														.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.
		512	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	E	L	S	N	V	Y	G	L	L	E	N	G	F	R	M	D	G	P	Q	G	C	P	P	S	V	Y	R	L	M	L	Q	C	W	N	W	S	P	S	D	R	P	R	F	R	D	I	H	F	N	L	E	N	L	I	S	S	N	S	L	N	D	E	V	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	S	N	P	E	V	I	R	A	L	E	R	G	Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	M	M	R	C	W	K	N	R	P	E	E	R	P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A	T	E	S	Q	E	E	I	P
Template Known Secondary structure													T	T							T	T													T		S	S	G	G	G	S												T	T	T	S		G	G	G
Template Predicted Secondary structure
Template SS confidence
		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.