Job Description P03949 Confidence 99.81% Date Fri May 3 21:46:51 BST 2013 Rank 348 Aligned Residues 187 % Identity 25% Template c1a81E_ PDB info PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam Resolution 3.00 Å

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		188	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.			.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.
Predicted Secondary structure																							.	.
Query SS confidence																							.	.
Query Sequence		S	L	D	K	Y	T	W	Y	H	G	K	I	S	R	S	D	S	E	A	I	L	.	.	G	S	G	I	T	G	S	F	L	V	R	E	S	E	T	S	I	G	Q	Y	T	I	S	V	R	H	D	G	R	V	F	H	Y	R	I	N	V	D	N	T	E	K	M	F	I	T	Q	E	V	K	F	R	T	L	G	E	L
Query Conservation																							.	.
Alig confidence																							.	.
Template Conservation
Template Sequence		S	A	N	H	L	P	F	F	F	G	N	I	T	R	E	E	A	E	D	Y	L	V	Q	G	G	M	S	D	G	L	Y	L	L	R	Q	S	R	N	Y	L	G	G	F	A	L	S	V	A	H	G	R	K	A	H	H	Y	T	I	E	R	E	L	N	G	T	Y	A	I	A	G	G	R	T	H	A	S	P	A	D	L
Template Known Secondary structure			G	G	G		T	T			S	S												T	T	T			T	T								S	S	S	T	T									S	S	S										T	T	T					T	T	S			B	S	S
Template Predicted Secondary structure
Template SS confidence
		9	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.
		266	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.								.	.	.	300	.	.	.	.				.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.
Predicted Secondary structure																																	.	.	.	.	.	.	.									.	.	.
Query SS confidence																																	.	.	.	.	.	.	.									.	.	.
Query Sequence		V	H	H	H	S	V	H	A	D	G	L	I	C	L	L	M	Y	P	A	S	K	K	D	K	G	R	G	L	F	S	L	.	.	.	.	.	.	.	S	P	N	A	P	D	E	W	.	.	.	E	L	D	R	S	E	I	I	M	H	N	K	L	G	G	G	Q	Y	G	D	V	Y	E	G	Y	W	K	R	H	D	C
Query Conservation																																	.	.	.	.	.	.	.									.	.	.
Alig confidence																																	.	.	.	.	.	.	.									.	.	.																					.
Template Conservation																																																																							.
Template Sequence		C	H	Y	H	S	Q	E	S	D	G	L	V	C	L	L	K	K	P	F	N	R	P	Q	G	V	Q	P	K	T	P	Q	L	E	K	L	I	A	T	T	A	H	E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	.	F	L	I	R	A	R	D	N	N	G
Template Known Secondary structure						T	T			T	T	S	S	S				S	B					T	T															T	S	G	G	G		T	T																S	S				T	T		.							S	S	S	S
Template Predicted Secondary structure																																																																							.
Template SS confidence
		89	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.		.	.	160	.	.	.	.	.	.	.
		336	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	I	A	V	K	A	L	K	E	D	A	M	P	L	H	E	F	L	A	E	A	A	I	M	K	D	L	H	H	K	N	L	V	R	L	L	G	V	C	T	H	E	A	P	F	Y	I	I	T	E	F	M	C	N	G	N	L	L	E	Y	L
Query Conservation
Alig confidence											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		S	Y	A	L	C	L	L	H	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	K	V	L	H	Y	R	I	D	K	D	K	T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V
Template Known Secondary structure										T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T											T	T	S					T	T	S			B	S
Template Predicted Secondary structure											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		202	.	.	.	.	.	.	.	210																						.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D