|   |   |
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | |
. | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
N | V | N | V | P | V | A | V | K | K | L | K | A | G | T | A | D | P | T | D | F | L | A | E | A | Q | I | M | K | K | L | . |
R | H | P | K | L | L | S | L | Y | A | V | C | T | R | D | E | P | I | L | I | V | T | E | L | M | Q | E | N | L | L | T | F | L | Q | R | R | G | R | Q | C | Q | M | P | Q | L | V | E | I |
| Query Conservation |   |
  |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
| . |   |
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|
|
|
|   |
|
| . | . | . | . | . | . | . |   |   |   |   |
|
|   |
|
|   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   | . | . | . | . | . | . |   |
|
|
|
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
| Template Sequence |   |
V | H | N | M | E | Y | A | V | K | V | I | D | . |
. |
. |
. |
. |
. |
. |
K | P | S | E | E | I | E | I | L | L | R | Y | G | Q | H | P | N | I | I | T | L | K | D | V | Y | . |
. |
. |
. |
. |
. |
D | L | V | T | E | L | M | R | G | G | E | L | L | D | K | I | L | R | Q | K | F | F | S | E | R | E | A | S | F | V |
| Template Known Secondary structure |   |
|
|
|
|
|  |  |  |
|
|
|
| . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  | T | T | S | T | T | B |
|
|  |  |  |
|
| . | . | . | . | . | . |
|
|  |  |
|
|
|
| S |
| B |  |  |  |  |  | T | S | S | S |
|
|
|  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
436 | . | . | . | 440 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . |
|   |
|   |   |
339 | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
S | A | Q | V | A | A | G | M | A | Y | L | E | E | M | N | F | I | H | R | D | L | A | A | R | N | I | L | I | N | N | S | L | S | V | K | I | A | D | F | G | L | A | R | I | L | M | K | E | N | E | Y | E | A | R | T | G | A | R | F | P | I | K | W | T | A | P | E | A | A | N | Y | N | R | F | T | T | K | S | D | V |
| Query Conservation |   |
  |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |
|
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| Template Sequence |   |
L | H | T | I | G | K | T | V | E | Y | L | H | S | Q | G | V | V | H | R | D | L | K | P | S | N | I | L | Y | V | D | E | S | G | N | P | E | C | L | R | I | C | D | . |
. |
. |
. |
F | G | F | A | K | Q | L | R | A | E | N | G | L | L | M | T | P | C | Y | T | E | V | L | K | R | Q | G | Y | D | E | G | C | D | I |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
|
| G | G | G |  |  |  | S | S | T | T |
|
| G | G | G |  |  |  |
|
| . | . | . | . |
| T | T |
|  |  |
| B |
| S | S |
|
| B |
|
| G | G | G |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
516 | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | |
|
|
|
. | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . |
|   |
|   |   |
419 | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | |
|
|
. | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | |
|
|
. | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | |
|
. | . | 490 |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  | . | . |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
| Query Sequence |   |
W | S | F | G | I | L | L | T | E | I | V | T | F | G | R | L | P | Y | . |
. |
. |
P | G | M | T | N | A | E | V | L | Q | Q | V | D | A | G | Y | R | M | P | C | P | . |
. |
. |
A | G | C | P | V | T | L | Y | D | I | M | Q | Q | C | W | R | S | D | P | D | K | R | P | T | F | E | T | L | Q | W | . |
. |
K | L | E |
| Query Conservation |   |
|
|   |
|
|
|
|   |
|
|   |
|   |
|   |   |
|
| . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
| . | . | . |   |   |   |
|   |   |   |   |   |
|
|   |   |
|
|   |   |   |
|   |   |
|
|
|   |   |   |
|   |   | . | . |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
| Template Conservation |   |
  |
|   |
|   |   |   |   |   |   |   |   | . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
|
|   |   |   |
| Template Sequence |   |
W | S | L | G | I | L | L | Y | T | M | L | A | . |
G | Y | T | P | F | A | N | G | P | S | D | T | P | E | E | I | L | T | R | I | G | S | G | K | F | T | L | S | G | G | N | W | N | T | V | S | E | T | A | K | D | L | V | S | K | M | L | H | V | D | P | H | Q | R | L | T | A | K | Q | V | L | Q | H | P | W | V | T |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
| S | S | T | T |
|
|  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
| S | G | G | G | G | G | S |
|  |  |  |  |  |  |  |  |  |  | S |
| S | S | T | T | S | S |
|
|  |  |  |  | T | T | S |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
598 | . | 600 | . | . | . | . | . | . | . | . | . | |
610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . |
|   |
|   |   |
491 | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | L | F | N | L | D | S | S | E | Y | K | E | A | S | I |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
Q | K | D | K | L | P | Q | S | Q | L | S | H | Q | D | L |
| Template Known Secondary structure |   |
| G | G | G | S |
|
| S |
|
|
|
|
|
|  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
677 | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . |
|   |