|   |   |
238 | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | |
260 | . | . | . | . | . | . | . | . | . | 270 | . | |
|
. | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  | . | . | . | . | . | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
| Query Sequence |   |
R | S | V | R | L | I | R | Q | I | G | A | G | Q | F | G | E | V | W | E | G | R | W | . |
N | V | N | V | P | V | A | V | K | K | L | K | . |
. |
A | G | T | A | D | P | T | D | F | L | A | E | A | Q | I | M | K | K | L | R | H | P | K | L | L | S | L | Y | A | V | C | T | R | D | E | P | I | . |
. |
. |
. |
. |
. |
| Query Conservation |   |
  |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   | . |   |   |   |   |   |
|
|
|
|   |
|   | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
| Template Conservation |   |
  |   |
|   |   |   |   |   |
|
|   |
| . |
|
|   |
|
|   |
|   |   |   |   |
|   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
T | D | F | E | P | I | Q | C | M | G | R | G | . |
F | G | V | V | F | E | A | K | N | K | V | D | D | C | N | Y | A | I | K | R | I | R | L | P | N | R | E | L | A | R | E | K | V | M | R | E | V | K | A | L | A | K | L | E | H | P | G | I | V | R | Y | F | N | A | W | L | E | T | P | P | E | K | W | Q | E | E | M |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
| . |
| S |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |
|
| S | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|
|
| T | T | B |
|
|  |  |  |  |  |  |  |
|
| S |
|  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  | . |
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
587 | . | . | 590 | . | . | . | . | . | . | . | . | |
. | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . |
|   |
|   |   |
|
|
|
|
|
|
|
309 | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | |
|
|
. | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
. | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
L | I | V | T | E | L | M | Q | E | N | L | L | T | F | L | Q | R | R | G | R | . |
. |
. |
Q | C | Q | M | P | Q | L | V | E | I | S | A | Q | V | A | A | G | M | A | Y | L | E | E | M | N | F | I | H | R | D | L | A | A | R | N | I | L | I | N | N | S | L | S | V | K | I | A | D | F | G |
| Query Conservation |   |
. | . | . | . | . | . | . |   |
|
|   |
|   |   |   |
|   |
|
|   |   |
|   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |
|
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
| Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
D | E | P | K | V | Y | L | Y | I | Q | M | Q | L | C | R | K | E | N | L | K | D | W | M | N | R | R | C | S | L | E | D | R | E | H | G | V | C | L | H | I | F | I | Q | I | A | E | A | V | E | F | L | H | S | K | G | L | M | H | R | D | L | K | P | S | N | I | F | F | T | M | D | D | V | V | K | V | G | D | F | G |
| Template Known Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |
|
|
| S | S |
|  |  |  |  |  |  | T |
|
| S | G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
|
|
|
|
| G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
|
| T |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
667 | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . |
|   |
|   |   |
379 | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | A | R | I | L | M | K | E | N | E | Y | E | A | R | T | G | A | R | F | P | I | K | W | T | A | P | E | A | A | N | Y | N | R | F | T | T | K | S | D | V | W | S | F | G | I | L | L | T | E | I | V | T | F | G | R | L | P | Y | P | G | M | T | N | A | E | V | L | Q | Q | V | D | A | G | Y | R | M | P | C | P | A |
| Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|
|
|   |
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|   | . |
|   |   |
|
| . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
| Template Sequence |   |
L | V | T | A | M | D | Q | D | T | H | G | Q | V | T | . |
. |
. |
. |
. |
. |
K | L | Y | M | S | P | E | Q | I | H | G | N | N | Y | S | H | K | V | D | I | F | S | L | G | L | I | L | F | E | L | L | Y | . |
S | F | S | T | Q | . |
. |
M | E | R | V | R | I | I | T | D | V | R | N | L | K | F | P | L | L | F | T |
| Template Known Secondary structure |   |
T |
|  |  |
| S |
|
|
|
|
|
|
|
| . | . | . | . | . | . | G | G | G | S |
|  |  |  |  |  |
|
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | . |
|
|
|
|  | . | . |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
956 | . | . | . | 960 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
970 | . | . | . | . | . | . | . | . | . | 980 | . | . | . | . | . | . | . | . | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | . | |
. | . | . | . | . | |
|
. | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020 | . | . | . | . | . | . |
|   |
|   |   |
459 | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | C | P | V | T | L | Y | D | I | M | Q | Q | C | W | R | S | D | P | D | K | R | P | T | F | E | T | L | Q | W |
| Query Conservation |   |
  |   |
|   |   |   |   |   |
|
|   |   |
|
|   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
| Template Sequence |   |
Q | K | Y | P | Q | E | H | M | M | V | Q | D | M | L | S | P | S | P | T | E | R | P | E | A | T | D | I | I | E |
| Template Known Secondary structure |   |
 |  |
|  |  |  |  |  |  |  |  |  |  |  |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1043 | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . |
|   |