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Job DescriptionO45539
Confidence100.00%DateSat Apr 13 12:48:12 BST 2013
Rank209Aligned Residues231
% Identity23%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   233......240.........250.........260. ........270.........280.........290.........300.........310.
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Query Sequence  WEVDRRSVRLIRQIGAGQFGEVWEGRWNV. NVPVAVKKLKAGTADPTDFLAEAQIMKKLRHPKLLSLYAVCTRDEPILIV
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Template Sequence  KQVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILK. . . . . . KEVIVANRVLQNSRHPFLTALKYSFQTHDRLCFV
Template Known Secondary structure  T


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   112.......120.........130.........140.........150. ........160.........170.........180.....
 
   312.......320.........330.........340.........350.. .......360.........370.........380.........390
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Query Sequence  TELMQENLLTFLQRRGRQCQMPQLVEISAQVAAGMAYLEEM. NFIHRDLAARNILINNSLSVKIADFGLARILMKENEYE
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Template Sequence  MEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEP. . . . . . .
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   227..230.........240.........250.........260.........270.........280.........290.........
 
   391........400.........410.........420.........430.........440.........450.........460.........470
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Query Sequence  ARTGARFPIKWTAPEAANYNRFTTKSDVWSFGILLTEIVTFGRLPYPGMTNAEVLQQVDAGYRMPCPAGCPVTLYDIMQQ
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Template Sequence  . . . . . . . . . EYLAPEVLEDNDYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILMEE. IRFPRTLGPEAKSLLSG
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   314.....320.........330.........340.... .....350.........360..... ....370.........380..
 
   471........ 480.......
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Query Sequence  CWRSDPDKR. . . . . PTFETLQW
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Template Sequence  LLKKDPKQRLGGGSEDAKEIMQ
Template Known Secondary structure  T
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   383......390.........400....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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