Job Description O45539 Confidence 100.00% Date Sat Apr 13 12:48:12 BST 2013 Rank 196 Aligned Residues 252 % Identity 24% Template c3mtfB_ PDB info PDB header:transferase Chain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor Resolution 2.15 Å

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		238	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.					.	.	.	.	.	.	.	.	310	.	.	.
Predicted Secondary structure																																																																		.	.	.	.
Query SS confidence																																																																		.	.	.	.
Query Sequence		R	S	V	R	L	I	R	Q	I	G	A	G	Q	F	G	E	V	W	E	G	R	W	N	V	N	V	P	V	A	V	K	K	L	K	A	G	T	A	D	P	T	D	F	L	A	E	A	Q	I	M	K	K	L	R	H	P	K	L	L	S	L	Y	A	V	.	.	.	.	C	T	R	D	E	P	I	L	I	V	T	E
Query Conservation																																																																		.	.	.	.
Alig confidence																								.																																										.	.	.	.
Template Conservation																								.
Template Sequence		R	D	I	T	L	L	E	C	V	G	K	G	R	Y	G	E	V	W	R	G	S	W	.	Q	G	E	N	V	A	V	K	I	F	S	S	R	D	E	K	S	W	F	R	E	T	E	L	Y	N	T	V	M	L	R	H	E	N	I	L	G	F	I	A	S	D	M	T	S	R	H	S	S	T	Q	L	W	L	I	T	H
Template Known Secondary structure		T	T											T	T									.	T	T										G	G	G														S					T	T	B												T	T
Template Predicted Secondary structure																								.
Template SS confidence
		206	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.		.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.
		314	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.									.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
Predicted Secondary structure																																											.	.	.	.	.	.	.	.
Query SS confidence																																											.	.	.	.	.	.	.	.
Query Sequence		L	M	Q	E	N	L	L	T	F	L	Q	R	R	G	R	Q	C	Q	M	P	Q	L	V	E	I	S	A	Q	V	A	A	G	M	A	Y	L	E	E	M	N	F	.	.	.	.	.	.	.	.	I	H	R	D	L	A	A	R	N	I	L	I	N	N	S	L	S	V	K	I	A	D	F	G	L	A	R	I	L	M	K
Query Conservation																																											.	.	.	.	.	.	.	.
Alig confidence															.																												.	.	.	.	.	.	.	.
Template Conservation															.
Template Sequence		Y	H	E	M	G	S	L	Y	D	Y	L	Q	L	.	T	T	L	D	T	V	S	C	L	R	I	V	L	S	I	A	S	G	L	A	H	L	H	I	E	I	F	G	T	Q	G	K	P	A	I	A	H	R	D	L	K	S	K	N	I	L	V	K	K	N	G	Q	C	C	I	A	D	L	G	L	A	V	M	H	S	Q
Template Known Secondary structure				T	T		B								.			B																					S		B		S	T	T		B						S			S	G	G	G					T	T	S								T	T						T
Template Predicted Secondary structure															.
Template SS confidence
		285	.	.	.	.	290	.	.	.	.	.	.	.		.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.
		386	.	.	.	390	.	.	.	.			.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.							.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.																.
Predicted Secondary structure											.	.																		.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence											.	.																		.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		E	N	E	Y	E	A	R	T	G	.	.	A	R	F	P	I	K	W	T	A	P	E	A	A	N	Y	N	R	.	.	.	.	.	.	F	T	T	K	S	D	V	W	S	F	G	I	L	L	T	E	I	V	T	F	G	R	L	P	Y	P	G	M	T	N	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A
Query Conservation											.	.																		.	.	.	.	.	.																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence											.	.																		.	.	.	.	.	.																				.											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																							.
Template Sequence		S	T	N	Q	L	D	V	G	N	N	P	R	V	G	T	K	R	Y	M	A	P	E	V	L	D	E	T	I	Q	V	D	C	F	D	S	Y	K	R	V	D	I	W	A	F	G	L	V	L	W	E	V	A	R	.	R	M	V	S	N	G	I	V	E	D	Y	K	P	P	F	Y	D	V	V	P	N	D	P	S	F	E
Template Known Secondary structure		T	T	T													G	G	G							T	T				T	T																						T	.	T	B		B	T	T	B							T	T	T	T	T	S		S	S
Template Predicted Secondary structure																																																							.
Template SS confidence
		364	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.		.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.
		443	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.							460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.
Predicted Secondary structure																			.	.	.	.	.	.
Query SS confidence																			.	.	.	.	.	.
Query Sequence		E	V	L	Q	Q	V	D	A	G	Y	R	M	P	C	P	A	G	.	.	.	.	.	.	C	P	V	T	L	Y	D	I	M	Q	Q	C	W	R	S	D	P	D	K	R	P	T	F	E	T	L	Q	W	K	L	E	D	L
Query Conservation																			.	.	.	.	.	.
Alig confidence																			.	.	.	.	.	.
Template Conservation
Template Sequence		D	M	R	K	V	V	C	V	D	Q	Q	R	P	N	I	P	N	R	W	F	S	D	P	T	L	T	S	L	A	K	L	M	K	E	C	W	Y	Q	N	P	S	A	R	L	T	A	L	R	I	K	K	T	L	T	K	I
Template Known Secondary structure								T	T	S								G	G	G	G	G	S																S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		443	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D