Job Description O45539 Confidence 100.00% Date Sat Apr 13 12:48:12 BST 2013 Rank 82 Aligned Residues 259 % Identity 34% Template c3fupB_ PDB info PDB header:transferase Chain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 2.40 Å

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		233	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.						.	.	.	.	.	.	.	.	270	.	.		.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.
Predicted Secondary structure																															.	.	.	.	.												.
Query SS confidence																															.	.	.	.	.												.
Query Sequence		W	E	V	D	R	R	S	V	R	L	I	R	Q	I	G	A	G	Q	F	G	E	V	W	E	G	R	W	N	V	.	.	.	.	.	N	V	P	V	A	V	K	K	L	K	A	.	G	T	A	D	P	T	D	F	L	A	E	A	Q	I	M	K	K	L	R	H	P	K	L	L	S	L	Y	A	V	C	T	R	D	E
Query Conservation																															.	.	.	.	.												.
Alig confidence																															.	.	.	.	.												.																																.	.
Template Conservation																																																																															.	.
Template Sequence		T	Q	F	E	E	R	H	L	K	F	L	Q	Q	L	G	K	G	N	F	G	S	V	E	M	C	R	Y	D	P	L	Q	D	N	T	G	E	V	V	A	V	K	K	L	Q	H	S	T	E	E	H	L	R	D	F	E	R	E	I	E	I	L	K	S	L	Q	H	D	N	I	V	K	Y	K	G	V	C	Y	.	.	S
Template Known Secondary structure		T				G	G	G											S	S										T	T	S	S	S											S																			T				T	T	B									.	.
Template Predicted Secondary structure																																																																															.	.
Template SS confidence
		842	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.			.
		307	.	.	310	.	.	.	.	.	.	.	.	.	320		.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
Predicted Secondary structure																.
Query SS confidence																.
Query Sequence		P	I	L	I	V	T	E	L	M	Q	E	N	L	L	.	T	F	L	Q	R	R	G	R	Q	C	Q	M	P	Q	L	V	E	I	S	A	Q	V	A	A	G	M	A	Y	L	E	E	M	N	F	I	H	R	D	L	A	A	R	N	I	L	I	N	N	S	L	S	V	K	I	A	D	F	G	L	A	R	I	L	M	K
Query Conservation																.
Alig confidence																.
Template Conservation
Template Sequence		N	L	K	L	I	M	E	Y	L	P	Y	G	S	L	R	D	Y	L	Q	K	H	K	E	R	I	D	H	I	K	L	L	Q	Y	T	S	Q	I	C	K	G	M	E	Y	L	G	T	K	R	Y	I	H	R	D	L	A	T	R	N	I	L	V	E	N	E	N	R	V	K	I	G	D	F	G	L	T	K	V	L	P	Q
Template Known Secondary structure											T	T		B					T	T	T	S	T	T	T																						T	T	T								G	G	G						T	T								T	T						T
Template Predicted Secondary structure
Template SS confidence
		924	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.
		386	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.																	.	440	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		E	N	E	Y	E	A	R	T	G	A	R	F	P	I	K	W	T	A	P	E	A	A	N	Y	N	R	F	T	T	K	S	D	V	W	S	F	G	I	L	L	T	E	I	V	T	F	G	R	L	P	Y	P	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	M	T	N	A	E	V	L	Q	Q	V	D
Query Conservation																																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence															.																																.								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation															.																																.
Template Sequence		D	K	E	K	V	K	E	P	G	E	S	P	I	.	F	W	Y	A	P	E	S	L	T	E	S	K	F	S	V	A	S	D	V	W	S	F	G	V	V	L	Y	E	L	F	T	.	Y	I	E	K	S	K	S	P	P	A	E	F	M	R	M	I	G	N	D	K	Q	G	Q	M	I	V	F	H	L	I	E	L	L	K
Template Known Secondary structure		T							S	S				G	.	G	G																														.	T	T		G	G	G	S											S				S	S
Template Predicted Secondary structure															.																																.
Template SS confidence
		1004	.	.	.	.	.	1010	.	.	.	.	.	.		.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.		.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.
		450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	G	Y	R	M	P	C	P	A	G	C	P	V	T	L	Y	D	I	M	Q	Q	C	W	R	S	D	P	D	K	R	P	T	F	E	T	L	Q	W	K	L	E	D	L	F	N	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		N	N	G	R	L	P	R	P	D	G	C	P	D	E	I	Y	M	I	M	T	E	C	W	N	N	N	V	N	Q	R	P	S	F	R	D	L	A	L	R	V	D	Q	I	R	D	Q
Template Known Secondary structure		T	T							T	T			T	T									T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1084	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D