Job Description O45539 Confidence 100.00% Date Sat Apr 13 12:48:12 BST 2013 Rank 203 Aligned Residues 235 % Identity 26% Template c3fmeA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 6; PDBTitle: crystal structure of human mitogen-activated protein kinase kinase 62 (mek6) activated mutant (s207d, t211d) Resolution 2.26 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		234	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.		260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.
Predicted Secondary structure																												.
Query SS confidence																												.
Query Sequence		E	V	D	R	R	S	V	R	L	I	R	Q	I	G	A	G	Q	F	G	E	V	W	E	G	R	W	.	N	V	N	V	P	V	A	V	K	K	L	K	A	G	T	A	D	P	T	D	F	L	A	E	A	Q	I	M	K	K	L	R	H	P	K	L	L	S	L	Y	A	V	C	T	R	D	E	P	I	L	I	V	T
Query Conservation																												.
Alig confidence																												.
Template Conservation
Template Sequence		E	V	K	A	D	D	L	E	P	I	M	E	L	G	R	G	A	Y	G	V	V	E	K	M	R	H	V	P	S	G	Q	I	M	A	V	K	R	I	R	N	S	Q	E	Q	K	R	L	L	M	D	L	D	I	S	M	R	T	V	D	C	P	F	T	V	T	F	Y	G	A	L	F	R	E	G	D	V	W	I	C	M
Template Known Secondary structure					G	G	G											S	S									T	T	T	T																										T	T				T	T	B										S	S	S
Template Predicted Secondary structure
Template SS confidence
		47	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.
		313	.	.	.	.	.	.	320	.	.	.				.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350		.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.
Predicted Secondary structure													.	.	.																												.
Query SS confidence													.	.	.																												.
Query Sequence		E	L	M	Q	E	N	L	L	T	F	L	.	.	.	Q	R	R	G	R	Q	C	Q	M	P	Q	L	V	E	I	S	A	Q	V	A	A	G	M	A	Y	L	E	.	E	M	N	F	I	H	R	D	L	A	A	R	N	I	L	I	N	N	S	L	S	V	K	I	A	D	F	G	L	A	R	I	L	M	K	E	N	E
Query Conservation													.	.	.																												.
Alig confidence													.	.	.																												.																															.	.	.	.	.	.	.	.
Template Conservation																																																																										.	.	.	.	.	.	.	.
Template Sequence		E	L	M	D	T	S	L	D	K	F	Y	K	Q	V	I	D	K	G	Q	T	I	P	E	D	I	L	G	K	I	A	V	S	I	V	K	A	L	E	H	L	H	S	K	L	S	V	I	H	R	D	V	K	P	S	N	V	L	I	N	A	L	G	Q	V	K	M	C	D	F	A	G	C	.	.	.	.	.	.	.	.
Template Known Secondary structure					S													T	T																										S								S	G	G	G					T	T					B							.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																																										.	.	.	.	.	.	.	.
Template SS confidence
		130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.
		389	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.			.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440			.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.
Predicted Secondary structure																									.	.																														.	.
Query SS confidence																									.	.																														.	.
Query Sequence		Y	E	A	R	T	G	A	R	F	P	I	K	W	T	A	P	E	A	A	N	Y	N	R	.	.	F	T	T	K	S	D	V	W	S	F	G	I	L	L	T	E	I	V	T	F	G	R	L	P	Y	P	G	M	T	.	.	N	A	E	V	L	Q	Q	V	D	A	G	Y	R	M	P	C	P	A	G	C	P	V	T	L
Query Conservation																									.	.																														.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.														.	.																				.										.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.																																			.
Template Sequence		.	.	.	.	.	.	.	.	.	.	K	P	Y	M	A	P	E	R	I	N	P	E	L	N	Q	Y	S	V	K	S	D	I	W	S	L	G	I	T	M	I	E	L	A	I	.	L	R	F	P	Y	D	S	W	G	T	P	F	Q	Q	L	K	Q	V	V	E	E	P	S	P	Q	L	P	A	D	K	F	S	A	E	F
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.				S						S			T	T																					.	T	S		S	S				S												S							T	T	T	S
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.																																			.
Template SS confidence
												217	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250		.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.
		465	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	D	I	M	Q	Q	C	W	R	S	D	P	D	K	R	P	T	F	E	T	L	Q	W
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	D	F	T	S	Q	C	L	K	K	N	S	K	E	R	P	T	Y	P	E	L	M	Q
Template Known Secondary structure									T		S	S	G	G	G	S							T	T
Template Predicted Secondary structure
Template SS confidence
		288	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D