|   |   |
233 | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . |
| Predicted Secondary structure |   |
|  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
W | E | V | D | R | R | S | V | R | L | I | R | Q | I | G | A | G | Q | F | G | E | V | W | E | G | R | W | N | V | N | V | P | V | A | V | K | K | L | K | A | G | T | A | D | P | T | D | F | L | A | E | A | Q | I | M | K | K | L | R | H | P | K | L | L | S | L | Y | A | V | C | T | R | D | E | P | I | L | I | V | T |
| Query Conservation |   |
  |   |
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   | . |   |   |   |   |
|
|
|
|   |
|   | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   | . | . |   |   |
|   |
| Template Sequence |   |
L | E | I | D | F | A | E | L | T | L | E | E | I | I | G | I | G | G | F | G | K | V | Y | R | A | F | W | . |
I | G | D | E | V | A | V | K | A | A | T | . |
. |
. |
. |
. |
I | E | N | V | R | Q | E | A | K | L | F | A | M | L | K | H | P | N | I | I | A | L | R | G | V | C | L | K | E | L | . |
. |
C | L | V | M |
| Template Known Secondary structure |   |
| B |
|
| T | T | S |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | . | T | T |  |  |  |  |  |  |  |
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  | . | . |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
137 | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | |
. | . | . | . | . | . | 170 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | |
|
. | . | . | . |
|   |
|   |   |
313 | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | |
|
|
. | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | L | M | Q | E | N | L | L | T | F | L | Q | R | R | G | R | Q | C | Q | M | P | Q | L | V | E | I | S | A | Q | V | A | A | G | M | A | Y | L | E | E | M | N | F | I | . |
. |
. |
H | R | D | L | A | A | R | N | I | L | I | N | N | S | L | S | V | K | I | A | D | F | G | L | A | R | I | L | M | K | E | N | E | Y |
| Query Conservation |   |
|   |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |
| . | . | . |
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |
| Template Sequence |   |
E | F | A | R | G | G | P | L | N | R | V | L | S | G | K | . |
R | I | P | P | D | I | L | V | N | W | A | V | Q | I | A | R | G | M | N | Y | L | H | D | E | A | I | V | P | I | I | H | R | D | L | K | S | S | N | I | L | I | L | Q | K | V | E | N | G | D | L | S | N | K | I | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
 |
|
| T | T |  |  |  |  |  |  |  | T | S | S | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S | S |
|
|
|
| S |
|
| S | G | G | G |  |  |  | S | S |
|
| S | S | S |
|
| S | S |
|
|  | . | . | . | . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
221 | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | |
. | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | |
|
|
|
|
|
|
|
|
|   |
|   |   |
390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | |
. | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | A | R | T | G | A | R | F | P | I | K | W | T | A | P | E | A | A | N | Y | N | R | F | T | T | K | S | D | V | W | S | F | G | I | L | L | T | E | I | V | T | F | G | R | L | P | Y | P | G | M | T | N | A | E | V | L | Q | Q | V | D | A | G | Y | . |
R | M | P | C | P | A | G | C | P | V | T | L | Y | D | I | M |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|
|
|   |
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   | . |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|   |
| . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
| Template Sequence |   |
K | I | T | D | F | G | L | G | A | Y | A | W | M | A | P | E | V | I | R | A | S | M | F | S | K | G | S | D | V | W | S | Y | G | V | L | L | W | E | L | L | T | . |
G | E | V | P | F | R | G | I | D | G | L | A | V | A | Y | G | V | A | M | N | K | L | A | L | P | I | P | S | T | C | P | E | P | F | A | K | L | M |
| Template Known Secondary structure |   |
 |  |
|
|
|
|
|
|
| G | G | G | S |
|  |  |  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
| T | T | T | T | S |
|  |  |  |  |  |  |  |  |  | T | S |
|
|
|
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
291 | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | |
. | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
469 | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 |
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | Q | C | W | R | S | D | P | D | K | R | P | T | F | E | T | L | Q | W | K | L | E |
| Query Conservation |   |
  |   |
|
|   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |   |
|   |
| Template Sequence |   |
E | D | C | W | N | P | D | P | H | S | R | P | S | F | T | N | I | L | D | Q | L | T |
| Template Known Secondary structure |   |
 |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
383 | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . |
|   |