Job Description O45539 Confidence 100.00% Date Sat Apr 13 12:48:12 BST 2013 Rank 83 Aligned Residues 249 % Identity 35% Template c3d4qA_ PDB info PDB header:transferase Chain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase Resolution 2.80 Å

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		231	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.				.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.
Predicted Secondary structure																																												.	.	.
Query SS confidence																																												.	.	.
Query Sequence		D	Q	W	E	V	D	R	R	S	V	R	L	I	R	Q	I	G	A	G	Q	F	G	E	V	W	E	G	R	W	N	V	N	V	P	V	A	V	K	K	L	K	A	.	.	.	G	T	A	D	P	T	D	F	L	A	E	A	Q	I	M	K	K	L	R	H	P	K	L	L	S	L	Y	A	V	C	T	R	D	E	P
Query Conservation																																												.	.	.
Alig confidence																																		.	.									.	.	.																													.
Template Conservation																																		.	.																																								.
Template Sequence		D	D	W	E	I	P	D	G	Q	I	T	V	G	Q	R	I	G	S	G	S	F	G	T	V	Y	K	G	K	W	H	G	D	.	.	V	A	V	K	M	L	N	V	T	A	P	T	P	Q	Q	L	Q	A	F	K	N	E	V	G	V	L	R	K	T	R	H	V	N	I	L	L	F	M	G	.	Y	S	T	K	P	Q
Template Known Secondary structure					B			T	T												T	T								S	S	S		.	.								S	S	S																	T	T				T	T	B						.				S	S	S
Template Predicted Secondary structure																																		.	.																																								.
Template SS confidence
		448	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.			480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.		.	520	.	.	.	.
		308	.	310	.	.	.	.	.	.		.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.
Predicted Secondary structure											.
Query SS confidence											.
Query Sequence		I	L	I	V	T	E	L	M	Q	.	E	N	L	L	T	F	L	Q	R	R	G	R	Q	C	Q	M	P	Q	L	V	E	I	S	A	Q	V	A	A	G	M	A	Y	L	E	E	M	N	F	I	H	R	D	L	A	A	R	N	I	L	I	N	N	S	L	S	V	K	I	A	D	F	G	L	A	R	I	L	M	K	E
Query Conservation											.
Alig confidence											.																																																																				.	.	.
Template Conservation																																																																															.	.	.
Template Sequence		L	A	I	V	T	Q	W	C	E	G	S	S	L	Y	H	H	L	H	I	I	E	T	K	F	E	M	I	K	L	I	D	I	A	R	Q	T	A	Q	G	M	D	Y	L	H	A	K	S	I	I	H	R	D	L	K	S	N	N	I	F	L	H	E	D	L	T	V	K	I	G	D	F	G	L	A	T	V	L	.	.	.
Template Known Secondary structure										S	S		B							T	S																										T	T		B		S			S	G	G	G					T	T	T								T	T		B			.	.	.
Template Predicted Secondary structure																																																																															.	.	.
Template SS confidence
		525	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.
		387	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.				.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.		.	.	.	.	.	.	450	.	.	.	.	.					.	.	.
Predicted Secondary structure																											.	.	.																																	.													.	.	.	.
Query SS confidence																											.	.	.																																	.													.	.	.	.
Query Sequence		N	E	Y	E	A	R	T	G	A	R	F	P	I	K	W	T	A	P	E	A	A	N	Y	N	R	.	.	.	F	T	T	K	S	D	V	W	S	F	G	I	L	L	T	E	I	V	T	F	G	R	L	P	Y	P	G	M	T	N	A	E	.	V	L	Q	Q	V	D	A	G	Y	R	M	P	.	.	.	.	C	P	A
Query Conservation																											.	.	.																																	.													.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.																	.	.	.																				.													.													.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.																																							.
Template Sequence		.	.	.	.	.	.	.	.	.	S	G	S	I	L	W	M	A	P	E	V	I	R	M	Q	D	K	N	P	Y	S	F	Q	S	D	V	Y	A	F	G	I	V	L	Y	E	L	M	T	.	G	Q	L	P	Y	S	N	I	N	N	R	D	Q	I	I	F	M	V	G	R	G	Y	L	S	P	D	L	S	K	V	R	S
Template Known Secondary structure		.	.	.	.	.	.	.	.	.					T	T							T	T		S	S				S																		.	S	S		T	T	T	T														T	S					G	G	G	S		T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.																																							.
Template SS confidence
											614	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.		.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.
		459	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	C	P	V	T	L	Y	D	I	M	Q	Q	C	W	R	S	D	P	D	K	R	P	T	F	E	T	L	Q	W	K	L	E	D	L	F	N	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		N	C	P	K	A	M	K	R	L	M	A	E	C	L	K	K	K	R	D	E	R	P	L	F	P	Q	I	L	A	S	I	E	L	L	A	R	S
Template Known Secondary structure		T	S												T		S	S	G	G	G	S																T
Template Predicted Secondary structure
Template SS confidence
		684	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D