Phyre 2 alignment of O45539 with c2vx3D

Job Description O45539
Confidence 100.00% Date Sat Apr 13 12:48:12 BST 2013

Rank 307 Aligned Residues 243

% Identity 19% Template c2vx3D_

PDB info PDB header:transferase Chain: D: PDB Molecule:dual specificity tyrosine-phosphorylation- regulated PDBTitle: crystal structure of the human dual specificity tyrosine-2 phosphorylation-regulated kinase 1a

Resolution 2.40 Å

	Insertion relative to template
	Deletion relative to template
	Catalytic residue from the CSA

Detailed help on interpreting your alignment

	238	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.		260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.							.	.	.	300	.	.	.	.	.	.	.	.	.	310
Predicted Secondary structure																							.																																						.	.	.	.	.	.
Query SS confidence																							.																																						.	.	.	.	.	.
Query Sequence	R	S	V	R	L	I	R	Q	I	G	A	G	Q	F	G	E	V	W	E	G	R	W	.	N	V	N	V	P	V	A	V	K	K	L	K	A	G	T	A	D	P	T	D	F	L	A	E	A	Q	I	M	K	K	L	R	H	P	K	L	L	.	.	.	.	.	.	S	L	Y	A	V	C	T	R	D	E	P	I	L	I
Query Conservation																							.																																						.	.	.	.	.	.
Alig confidence																							.																																						.	.	.	.	.	.
Template Conservation
Template Sequence	D	R	Y	E	I	D	S	L	I	G	K	G	S	F	G	Q	V	V	K	A	Y	D	R	V	E	Q	E	W	V	A	I	K	I	I	K	N	K	K	A	F	L	N	Q	A	Q	I	E	V	R	L	L	E	L	M	N	K	H	D	T	E	M	K	Y	Y	I	V	H	L	K	R	H	F	M	F	R	N	H	L	C	L
Template Known Secondary structure	T	T											T	T									T	T	T	T										S	S																				S	S	S	S	G	G	G	G	B										T	T
Template Predicted Secondary structure
Template SS confidence
	157	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.

	311	.	.	.	.	.	.	.	.	320	.		.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.					.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
Predicted Secondary structure												.																																	.	.	.	.
Query SS confidence												.																																	.	.	.	.
Query Sequence	V	T	E	L	M	Q	E	N	L	L	T	.	F	L	Q	R	R	G	R	Q	C	Q	M	P	Q	L	V	E	I	S	A	Q	V	A	A	G	M	A	Y	L	E	E	M	N	.	.	.	.	F	I	H	R	D	L	A	A	R	N	I	L	I	N	N	S	L	S	V	K	I	A	D	F	G	L	A	R	I	L	M	K
Query Conservation												.																																	.	.	.	.
Alig confidence												.																																	.	.	.	.
Template Conservation
Template Sequence	V	F	E	M	L	S	Y	N	L	Y	D	L	L	R	N	T	N	F	R	G	V	S	L	N	L	T	R	K	F	A	Q	Q	M	C	T	A	L	L	F	L	A	T	P	E	L	S	I	I	H	C	D	L	K	P	E	N	I	L	L	C	N	P	K	R	S	A	I	K	I	V	D	F	G	S	S	C	Q	L	G	Q
Template Known Secondary structure								B								T	T	T																								S	T	T	T					S				G	G	G				S	S	T	T	S									T	T				T	T
Template Predicted Secondary structure
Template SS confidence
	237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.

	386	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450
Predicted Secondary structure																																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence	E	N	E	Y	E	A	R	T	G	A	R	F	P	I	K	W	T	A	P	E	A	A	N	Y	N	R	F	T	T	K	S	D	V	W	S	F	G	I	L	L	T	E	I	V	T	F	G	R	L	P	Y	P	G	M	T	N	A	E	V	L	Q	Q	V	D	A	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence									.	.	.	.	.	.																																.																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation									.	.	.	.	.	.																																.
Template Sequence	R	I	Y	Q	I	Q	S	R	.	.	.	.	.	.	F	Y	R	S	P	E	V	L	L	G	M	P	Y	D	L	A	I	D	M	W	S	L	G	C	I	L	V	E	M	H	T	.	G	E	P	L	F	S	G	A	N	E	V	D	Q	M	N	K	I	V	E	V	L	G	I	P	P	A	H	I	L	D	Q	A	P	K
Template Known Secondary structure								G	.	.	.	.	.	.	G	G							T	T					T																	.	S	S		S	S			S	S														S							T	T		T	T
Template Predicted Secondary structure									.	.	.	.	.	.																																.
Template SS confidence
	317	.	.	320	.	.	.	.							.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.		.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.

																																														451	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.
Predicted Secondary structure	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	Y	R	M	P	C	P	A	G	C	P	V	T	L	Y	D	I	M	Q	Q	C	W	R	S	D	P	D	K	R	P	T	F	E	T	L
Query Conservation	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence	A	R	K	F	F	E	K	L	P	D	G	T	W	N	L	K	K	T	K	R	E	Y	K	P	P	G	T	R	K	L	H	N	I	L	G	V	E	T	G	G	P	G	G	R	R	A	G	E	S	G	H	T	V	A	D	Y	L	K	F	K	D	L	I	L	R	M	L	D	Y	D	P	K	T	R	I	Q	P	Y	Y	A
Template Known Secondary structure	G	G	G	T					T	T	S											S			T	T		S						T	T	T	T	T	T	S	G	G	G	T	T	T	T		T	T																	T		S		T	T	T	S
Template Predicted Secondary structure
Template SS confidence
	391	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470

	486	.
Predicted Secondary structure
Query SS confidence
Query Sequence	Q	W
Query Conservation
Alig confidence
Template Conservation
Template Sequence	L	Q
Template Known Secondary structure		T
Template Predicted Secondary structure
Template SS confidence
	474	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server

Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]

© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys
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Phyre2 is part of Genome3D