|   |   |
234 | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . |
| Predicted Secondary structure |   |
 |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | V | D | R | R | S | V | R | L | I | R | Q | I | G | A | G | Q | F | G | E | V | W | E | G | R | W | N | V | N | V | P | V | A | V | K | K | L | K | A | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | A | D | P | T | D | F | L | A | E | A | Q | I | M | K | K | L | R | H | P | K | L | L | S | L | Y | A | V | C |
| Query Conservation |   |
  |
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |   |
|   |
|
|   |   |   |   |   |   |   | . | . |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
| Template Sequence |   |
D | K | S | G | R | Q | W | K | L | K | S | F | Q | T | R | D | N | Q | G | I | L | Y | E | A | A | P | T | S | K | . |
. |
F | S | L | K | L | D | A | K | D | G | R | L | F | N | E | Q | N | F | F | Q | R | A | A | K | P | L | Q | V | N | K | W | K | K | L | Y | S | T | P | L | L | A | I | P | T | C | M | G | F | G |
| Template Known Secondary structure |   |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
|
|
| . | . |  |  |  |  |  |  |  | T | T | S | T |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  | T | T |
| T | T |
| S |
|
|
|
|
|  |  |  |
| Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|  | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | |
|
. | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . |
|   |
|   |   |
303 | . | . | . | . | |
. | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | |
330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | |
|
. | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|
|  | . |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
| Query Sequence |   |
T | R | D | E | P | . |
I | L | I | V | T | E | L | M | Q | E | N | L | L | T | F | L | Q | R | R | G | R | Q | . |
C | Q | M | P | Q | L | V | E | I | S | A | Q | V | A | A | G | M | A | Y | L | E | E | M | N | F | I | H | R | D | L | A | A | R | N | I | L | I | N | N | S | L | S | V | K | . |
. |
I | A | D | F | G |
| Query Conservation |   |
  |   |   |   |   | . |   |   |
|
|   |
|   |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |
|
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |
| . | . |
|   |
|
|
|
| Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
| Template Sequence |   |
V | H | Q | D | K | Y | R | F | L | V | L | P | S | L | G | R | S | L | Q | S | A | L | D | V | S | P | K | H | V | L | S | E | R | S | V | L | Q | V | A | C | R | L | L | D | A | L | E | F | L | H | E | N | E | Y | V | H | G | N | V | T | A | E | N | I | F | V | D | P | E | D | Q | S | Q | V | T | L | A | G | Y | G |
| Template Known Secondary structure |   |
 |  | T | T | T |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  | S | G | G | G |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| B |
| S |
|
|
| G | G | G |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
| G | G |
| Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
249 | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . |
|   |
|   |   |
379 | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
440 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  | . | . | . | . | . |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | A | R | I | L | M | K | E | N | E | Y | E | A | R | . |
. |
. |
. |
. |
T | G | A | R | F | P | I | K | W | T | A | P | E | A | A | N | Y | N | R | F | T | T | K | S | D | V | W | S | F | G | I | L | L | T | E | I | V | T | F | G | R | L | P | Y | P | G | M | . |
. |
. |
. |
. |
T | N | A | E | V | L | Q | Q | V |
| Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|
|
|   |
|
|   |
|   |
|   |   |
|
|   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |
|   |   |
|
|   | . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
F | A | F | R | Y | C | P | S | G | K | H | V | A | Y | V | E | G | S | R | S | P | H | E | G | D | L | E | F | I | S | M | D | L | H | K | G | C | G | P | S | R | R | S | D | L | Q | S | L | G | Y | C | M | L | K | W | L | Y | . |
G | F | L | P | W | T | N | C | L | P | N | T | E | D | I | M | K | Q | K | Q | K | F |
| Template Known Secondary structure |   |
G |
| B |
| S | S | G | G | G |
|
|
|
|
|
| T | T | S | S |
| T | T |
| S |
| T | T | T |
|
|  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S |
|
| T | T | G | G | G | T | T |
|  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
329 | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | |
. | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . |
|   |
|   |   |
449 | 450 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | A | G | Y | R | M | P | C | P | A | . |
. |
. |
. |
. |
G | C | P | V | T | L | Y | D | I | M | Q | Q | C | W | R | S | D | P | D | K | R | P | T | F | E | T | L | Q | W | K | L | E | D | L | F | N | L | D | S | S | E | Y | K | E |
| Query Conservation |   |
  |   |
|   |   |   |   |   |
|   | . | . | . | . | . |   |   |
|   |   |   |   |   |
|
|   |   |
|
|   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|
| Template Sequence |   |
V | D | K | P | G | P | F | V | G | P | C | G | H | W | I | R | P | S | E | T | L | Q | K | Y | L | K | V | V | M | A | L | T | Y | E | E | K | P | P | Y | A | M | L | R | N | N | L | E | A | L | L | Q | D | L | R | V | S | P | Y | D |
| Template Known Secondary structure |   |
 |  | S |
|
|
|  |  |
| T | T | S |
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T |
|
| T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | S |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
408 | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . |
|   |