|   |   |
238 | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | |
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | |
. | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | S | V | R | L | I | R | Q | I | G | A | G | Q | F | G | E | V | W | E | G | R | W | . |
N | V | N | V | P | V | A | V | K | K | L | K | A | G | T | A | D | P | T | D | F | L | A | E | A | Q | I | M | K | K | L | . |
R | H | P | K | L | L | S | L | Y | A | V | C | T | R | D | E | P | I | L | I | V | T | E | L | M |
| Query Conservation |   |
  |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   | . |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
| . |   |
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
| Template Sequence |   |
T | E | F | H | E | L | E | K | I | G | S | G | E | F | G | S | V | F | K | C | V | K | R | L | D | G | C | I | Y | A | I | K | R | S | K | K | P | S | V | D | E | Q | N | A | L | R | E | V | Y | A | H | A | V | L | G | Q | H | S | H | V | V | R | Y | F | S | A | W | A | E | D | D | H | M | L | I | Q | N | E | Y | C |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| S |
| T | T | B |
|
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
|
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
297 | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . |
|   |
|   |   |
316 | . | . | . | 320 | . | . | . | . | . | . | . | |
|
|
|
. | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
| . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | E | N | L | L | T | F | L | Q | R | R | G | . |
. |
. |
. |
R | Q | C | Q | M | P | Q | L | V | E | I | S | A | Q | V | A | A | G | M | A | Y | L | E | E | M | N | F | I | H | R | D | L | A | A | R | N | I | L | I | N | N | S | L | S | V | K | I | A | D | F | G | L | A | R | I | L | M | K | E | N | E | Y | E | A |
| Query Conservation |   |
  |
|   |
|
|   |   |
|   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |
|
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
N | G | G | S | L | A | D | A | I | S | E | N | Y | R | I | M | S | Y | F | K | E | A | E | L | K | D | L | L | L | Q | V | G | R | G | L | R | Y | I | H | S | M | S | L | V | H | M | D | I | K | P | S | N | I | F | I | S | K | V | . |
M | F | K | I | G | D | L | G | H | V | T | R | I | S | S | P | Q | V | E | E | G |
| Template Known Secondary structure |   |
T | T |
| B |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
| S | G | G | G |  |  |  |
|
|
| . |
|  |  |  |
|
|
| T | T |
|  |  | T | T |
| S | S |
|
|
|
|
| Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | |
. | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . |
|   |
|   |   |
392 | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | |
. | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 |
| Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | T | G | A | R | F | P | I | K | W | T | A | P | E | A | A | N | Y | N | R | . |
F | T | T | K | S | D | V | W | S | F | G | I | L | L | T | E | I | V | T | F | G | R | L | P | Y | P | G | M | T | N | A | E | V | L | Q | Q | V | D | A | G | Y | R | M | P | C | P | A | G | C | P | V | T | L | Y | D | I | M | Q | Q |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   | . |   |
|   |
|
|
|
|
|
|   |
|
|
|
|   |
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |
| Alig confidence |   |
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  | . | . | . | . | . | . |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |
|
|   |   | . |   |   |
|   |   |   |   | . | . | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |
| Template Sequence |   |
D | . |
. |
. |
. |
. |
. |
S | R | F | L | A | N | E | V | L | Q | E | N | Y | T | H | L | P | K | A | D | I | F | A | L | A | L | T | V | V | C | A | A | G | . |
A | E | P | L | P | R | N | . |
. |
. |
G | D | Q | W | H | E | I | R | Q | G | R | L | P | R | I | P | Q | V | L | S | Q | E | F | T | E | L | L | K | V |
| Template Known Secondary structure |   |
| . | . | . | . | . | . | G | G | G |
|
|  |  |  |  | T | T |
|
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . |
|
|
|
|
| S | S | . | . | . |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
| . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
479 | |
|
|
|
|
|
480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | |
. | . | . | . | . | . | . | |
|
|
520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . |
|   |
|   |   |
471 | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
C | W | R | S | D | P | D | K | R | P | T | F | E | T | L | Q | W |
| Query Conservation |   |
|
|   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |
|   |   |
|
|
|   |   |   |
|
|   |
| Template Sequence |   |
M | I | H | P | D | P | E | R | R | P | S | A | M | A | L | V | K |
| Template Known Secondary structure |   |
 | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
549 | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . |
|   |