Job Description O45539 Confidence 100.00% Date Sat Apr 13 12:48:12 BST 2013 Rank 87 Aligned Residues 250 % Identity 36% Template c1xkkA_ PDB info PDB header:transferase Chain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016 Resolution 2.40 Å

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		235	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.		260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.
Predicted Secondary structure																											.
Query SS confidence																											.
Query Sequence		V	D	R	R	S	V	R	L	I	R	Q	I	G	A	G	Q	F	G	E	V	W	E	G	R	W	.	N	V	N	V	P	V	A	V	K	K	L	K	A	G	T	A	D	P	T	D	F	L	A	E	A	Q	I	M	K	K	L	R	H	P	K	L	L	S	L	Y	A	V	C	T	R	D	E	P	I	L	I	V	T	E
Query Conservation																											.
Alig confidence																											.														.	.
Template Conservation																																									.	.
Template Sequence		L	K	E	T	E	F	K	K	I	K	V	L	G	S	G	A	F	G	T	V	Y	K	G	L	W	I	P	V	K	I	P	V	A	I	K	E	L	R	E	.	.	K	A	N	K	E	I	L	D	E	A	Y	V	M	A	S	V	D	N	P	H	V	C	R	L	L	G	I	C	L	T	S	T	V	Q	L	I	T	Q	L
Template Known Secondary structure				T	T	T											S	S																							.	.		T																	T	T	B									S	S	S
Template Predicted Secondary structure																																									.	.
Template SS confidence
		707	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.			.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.
		314	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	M	Q	E	N	L	L	T	F	L	Q	R	R	G	R	Q	C	Q	M	P	Q	L	V	E	I	S	A	Q	V	A	A	G	M	A	Y	L	E	E	M	N	F	I	H	R	D	L	A	A	R	N	I	L	I	N	N	S	L	S	V	K	I	A	D	F	G	L	A	R	I	L	M	K	E	N	E	Y	E	A	R	T
Query Conservation
Alig confidence																																																																															.	.	.
Template Conservation																																																																															.	.	.
Template Sequence		M	P	F	G	C	L	L	D	Y	V	R	E	H	K	D	N	I	G	S	Q	Y	L	L	N	W	C	V	Q	I	A	K	G	M	N	Y	L	E	D	R	R	L	V	H	R	D	L	A	A	R	N	V	L	V	K	T	P	Q	H	V	K	I	T	D	F	G	L	A	K	L	L	G	A	E	E	K	V	P	.	.	.
Template Known Secondary structure			T	T		B								T	S	S	S																							T	T				S				G	G	G						T	T								S					T	T	T	T					.	.	.
Template Predicted Secondary structure																																																																															.	.	.
Template SS confidence
		793	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.
		394	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	A	R	F	P	I	K	W	T	A	P	E	A	A	N	Y	N	R	F	T	T	K	S	D	V	W	S	F	G	I	L	L	T	E	I	V	T	F	G	R	L	P	Y	P	G	M	T	N	A	E	V	L	Q	Q	V	D	A	G	Y	R	M	P	C	P	A	G	C	P	V	T	L	Y	D	I	M	Q	Q	C	W	R
Query Conservation
Alig confidence		.	.	.	.	.
Template Conservation		.	.	.	.	.
Template Sequence		.	.	.	.	.	I	K	W	M	A	L	E	S	I	L	H	R	I	Y	T	H	Q	S	D	V	W	S	Y	G	V	T	V	W	E	L	M	T	F	G	S	K	P	Y	D	G	I	P	A	S	E	I	S	S	I	L	E	K	G	E	R	L	P	Q	P	P	I	C	T	I	D	V	Y	M	I	M	V	K	C	W	M
Template Known Secondary structure		.	.	.	.	.	T	T	T	S																												T	T	S			T	T	T	T	S		G	G	G								T							T	T	B												T
Template Predicted Secondary structure		.	.	.	.	.
Template SS confidence
							878	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.
		474	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	D	P	D	K	R	P	T	F	E	T	L	Q	W	K	L	E	D	L	F	N
Query Conservation
Alig confidence
Template Conservation
Template Sequence		I	D	A	D	S	R	P	K	F	R	E	L	I	I	E	F	S	K	M	A	R
Template Known Secondary structure		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		953	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D