Job Description O45539 Confidence 100.00% Date Sat Apr 13 12:48:12 BST 2013 Rank 6 Aligned Residues 428 % Identity 39% Template c1k9aB_ PDB info PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution Resolution 2.50 Å Model Dimensions (Å) X:82.593 Y:76.164 Z:53.365

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		53	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.							.	120	.	.	.	.	.	.
Predicted Secondary structure																																																																				.	.	.	.	.	.
Query SS confidence																																																																				.	.	.	.	.	.
Query Sequence		N	Q	N	I	S	Q	S	A	N	F	V	A	L	F	Q	Y	D	A	R	T	D	D	D	L	S	F	K	K	D	D	I	L	E	I	L	N	D	T	Q	G	D	W	W	F	A	R	H	K	A	T	G	R	T	G	Y	I	P	S	N	Y	V	A	R	E	K	S	.	.	.	.	.	.	I	E	S	Q	P	W	Y	F
Query Conservation																																																																				.	.	.	.	.	.
Alig confidence																																																																				.	.	.	.	.	.
Template Conservation
Template Sequence		Q	A	S	W	P	S	G	T	E	C	I	A	K	Y	N	F	H	G	T	A	E	Q	D	L	P	F	C	K	G	D	V	L	T	I	V	A	V	T	K	D	P	N	W	Y	K	A	K	N	K	V	G	R	E	G	I	I	P	A	N	Y	V	Q	K	R	E	G	V	K	A	G	T	K	L	S	L	M	P	W	F	H
Template Known Secondary structure			S				T	T						S	S		B			S	S	T	T	B			B		T	T										S	S	T	T							T	T	S							G	G	G										S	S	S			S		T	T	B
Template Predicted Secondary structure
Template SS confidence
		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.
		127	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	K	M	R	R	I	D	A	E	K	C	L	L	H	T	L	N	E	H	G	A	F	L	V	R	D	S	E	S	R	Q	H	D	L	S	L	S	V	R	E	N	D	S	V	K	H	Y	R	I	R	Q	L	D	H	G	G	Y	F	I	A	R	R	R	P	F	A	T	L	H	D	L	I	A	H	Y	Q	R	E	A	D
Query Conservation
Alig confidence														.	.																																						.
Template Conservation														.	.																																						.
Template Sequence		G	K	I	T	R	E	Q	A	E	R	L	L	.	.	Y	P	P	E	T	G	L	F	L	V	R	E	S	T	N	Y	P	G	D	Y	T	L	C	V	S	C	E	G	K	V	E	H	Y	R	I	M	Y	.	H	A	S	K	L	S	I	D	E	E	V	Y	F	E	N	L	M	Q	L	V	E	H	Y	T	T	D	A	D
Template Known Secondary structure			S										T	.	.		S			T	T								S	S	S	T	T									T	T										.		T	T				S	S	S	S	S		B	S	S													T
Template Predicted Secondary structure														.	.																																						.
Template SS confidence
		85	.	.	.	.	90	.	.	.	.	.	.			.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.		.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.
		207	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	L	C	V	N	L	G	A	P	C	A	K	S	E	A	P	Q	T	T	T	F	T	Y	D	D	Q	W	E	V	D	R	R	S	V	R	L	I	R	Q	I	G	A	G	Q	F	G	E	V	W	E	G	R	W	N	V	N	V	P	V	A	V	K	K	L	K	A	G	T	A	D	P	T	D	F	L	A	E	A	Q	I
Query Conservation
Alig confidence																																																								.													.
Template Conservation																																																								.													.
Template Sequence		G	L	C	T	R	L	I	K	P	K	V	M	E	G	T	V	A	A	Q	D	E	F	Y	R	S	G	W	A	L	N	M	K	E	L	K	L	L	Q	T	I	G	K	G	E	F	G	D	V	M	L	G	D	Y	R	.	G	N	K	V	A	V	K	C	I	K	N	D	.	A	T	A	Q	A	F	L	A	E	A	S	V
Template Known Secondary structure		T	S	S	S				S	B				S	S											T	T		B			G	G	G											T	T									T	.	T									S	S		.	T	T	S
Template Predicted Secondary structure																																																								.													.
Template SS confidence
		162	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.		.	.	.	.	220	.	.	.	.	.	.	.		.	.	230	.	.	.	.	.	.	.	.	.
		287	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.		.	.	.	310	.	.	.	.	.	.	.	.	.	320		.	.	.	.	.		.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.
Predicted Secondary structure																						.															.						.
Query SS confidence																						.															.						.
Query Sequence		M	K	K	L	R	H	P	K	L	L	S	L	Y	A	V	C	T	R	D	E	.	P	I	L	I	V	T	E	L	M	Q	E	N	L	L	.	T	F	L	Q	R	.	R	G	R	Q	C	Q	M	P	Q	L	V	E	I	S	A	Q	V	A	A	G	M	A	Y	L	E	E	M	N	F	I	H	R	D	L	A	A	R	N
Query Conservation																						.															.						.
Alig confidence																						.															.						.
Template Conservation
Template Sequence		M	T	Q	L	R	H	S	N	L	V	Q	L	L	G	V	I	V	E	E	K	G	G	L	Y	I	V	T	E	Y	M	A	K	G	S	L	V	D	Y	L	R	S	R	G	R	S	V	L	G	G	D	C	L	L	K	F	S	L	D	V	C	E	A	M	E	Y	L	E	G	N	N	F	V	H	R	D	L	A	A	R	N
Template Known Secondary structure			T	T				T	T	B										S	S	S										T	T		B										T	T	T																							T	T		B		S				G	G	G
Template Predicted Secondary structure
Template SS confidence
		240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.
		364	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	L	I	N	N	S	L	S	V	K	I	A	D	F	G	L	A	R	I	L	M	K	E	N	E	Y	E	A	R	T	G	A	R	F	P	I	K	W	T	A	P	E	A	A	N	Y	N	R	F	T	T	K	S	D	V	W	S	F	G	I	L	L	T	E	I	V	T	F	G	R	L	P	Y	P	G	M	T	N	A	E
Query Conservation
Alig confidence																				.	.	.	.	.	.	.	.	.	.	.
Template Conservation																				.	.	.	.	.	.	.	.	.	.	.
Template Sequence		V	L	V	S	E	D	N	V	A	K	V	S	D	F	G	L	T	K	.	.	.	.	.	.	.	.	.	.	.	E	A	G	K	L	P	V	K	W	T	A	P	E	A	L	R	E	K	K	F	S	T	K	S	D	V	W	S	F	G	I	L	L	W	E	I	Y	S	F	G	R	V	P	Y	P	R	I	P	L	K	D
Template Known Secondary structure						T	T									T	T		B	.	.	.	.	.	.	.	.	.	.	.							T	T	T	S						T	T	T																				T	T	T			S	S	T	T	S		T	T	T
Template Predicted Secondary structure																				.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.												.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.
		444	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	L	Q	Q	V	D	A	G	Y	R	M	P	C	P	A	G	C	P	V	T	L	Y	D	I	M	Q	Q	C	W	R	S	D	P	D	K	R	P	T	F	E	T	L	Q	W	K	L	E	D	L	F	N	L	D
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	V	P	R	V	E	K	G	Y	K	M	D	A	P	D	G	C	P	P	A	V	Y	D	V	M	K	N	C	W	H	L	D	A	A	T	R	P	T	F	L	Q	L	R	E	Q	L	E	H	I	R	T	H	E
Template Known Secondary structure							T	T	T							T	T													T		S	S	G	G	G	S																	T
Template Predicted Secondary structure
Template SS confidence
		395	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.