Job Description O01325 Confidence 100.00% Date Fri May 3 21:21:05 BST 2013 Rank 7 Aligned Residues 359 % Identity 33% Template c4fl2A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch Resolution 2.19 Å Model Dimensions (Å) X:60.699 Y:88.565 Z:50.598

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		87	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.					.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150		.	.	.	.	.	.	.	.	.	160	.
Predicted Secondary structure																						.	.	.	.																																													.
Query SS confidence																						.	.	.	.																																													.
Query Sequence		D	D	E	P	F	Y	H	G	Y	M	S	R	E	E	S	E	K	L	V	R	.	.	.	.	S	Q	G	E	F	L	L	R	K	T	E	L	T	K	R	G	E	V	V	V	L	S	V	F	W	D	E	G	V	H	H	L	V	V	E	K	A	N	N	G	L	Y	Y	L	.	K	E	F	C	F	E	N	I	S	D	L
Query Conservation																						.	.	.	.																																													.
Alig confidence																						.	.	.	.															.	.	.																												.
Template Conservation																																								.	.	.
Template Sequence		E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	D	N	N	G	.	.	.	S	Y	A	L	C	L	L	H	E	G	K	V	L	H	Y	R	I	D	K	D	K	T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L
Template Known Secondary structure		G	G	S	T	T	B			S												S	S	S			T	T									T	T	T	.	.	.									T	T											T	T	S				S	T	T				B	S	S
Template Predicted Secondary structure																																								.	.	.
Template SS confidence
		164	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.				.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
		162	.	.	.	.	.	.	.	170	.	.	.	.	.	.																		.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200									.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.
Predicted Secondary structure																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.	.
Query SS confidence																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.	.
Query Sequence		V	R	Y	H	H	Q	T	R	A	S	V	Y	K	S	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	I	K	L	F	S	W	V	V	R	E	E	W	Q	L	Y	H	E	Q	I	N	L	G	K	K	.	.	.	.	.	.	.	.	L	G	N	G	E	F	G	E	V	F	Q	G	V	L	S	V
Query Conservation																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.	.
Alig confidence																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.	.																.
Template Conservation																																																																																	.
Template Sequence		V	E	H	Y	S	Y	K	A	D	G	L	L	R	V	L	T	V	P	C	Q	K	I	G	T	Q	R	E	A	L	P	M	D	T	E	V	Y	E	S	P	Y	A	D	P	E	E	I	R	P	K	E	V	Y	L	D	R	K	L	L	T	L	E	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	.
Template Known Secondary structure						T	T	B		T	T	S	S	S				S	B				S				T	T			G	G	G	S	G	G	G	S		G	G	G	S	T	T	S				S	S	S	B			G	G	G												T	T										.
Template Predicted Secondary structure																																																																																	.
Template SS confidence
		241	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.
		217	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	I	F	T	N	D	V	E	V	A	V	K	T	M	K	G	S	K	V	T	A	D	E	R	I	T	F	L	R	E	A	N	L	M	L	K	L	N	H	K	Y	V	V	R	L	Y	G	V	A	T	Q	Q	E	P	I	M	I	V	M	E	L	C	S	G	G	C	L	K	S	R	I	E	K	K	D	E	Q	L	S	D
Query Conservation
Alig confidence		.																																																	.																											.
Template Conservation		.																																																	.																											.
Template Sequence		.	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	.	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	R	H	.	V	K	D
Template Known Secondary structure		.		T	T												S	G	G	G		G	G	G																	T	T	B								.		S	S	S									T	T		B									T	T	.	S
Template Predicted Secondary structure		.																																																	.																											.
Template SS confidence
			392	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.		.	.	.
		297	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350					.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.
Predicted Secondary structure																																																								.	.	.	.
Query SS confidence																																																								.	.	.	.
Query Sequence		V	L	K	R	K	Y	C	K	Q	I	A	K	G	M	R	Y	L	E	K	K	Q	V	I	H	R	D	L	A	A	R	N	V	L	L	D	K	S	D	N	C	K	I	S	D	F	G	L	S	L	F	G	K	L	H	.	.	.	.	K	E	Q	K	L	M	K	V	P	I	R	W	L	A	P	E	T	L	L	K	G	I
Query Conservation																																																								.	.	.	.
Alig confidence																																																								.	.	.	.
Template Conservation
Template Sequence		K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K
Template Known Secondary structure																					T	T				S			S	G	G	G						T	T							T	T					T	T								S		B	T	T	B		G	G	G	G
Template Predicted Secondary structure
Template SS confidence
		469	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.
		373	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.		.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.
Predicted Secondary structure																					.
Query SS confidence																					.
Query Sequence		Y	S	S	K	S	D	V	W	S	F	G	V	V	M	F	E	V	F	S	.	G	E	Y	P	Y	A	D	V	K	V	L	K	E	L	R	R	K	V	A	H	E	N	L	R	L	K	P	P	S	D	M	P	T	D	D	A	K	V	M	E	M	C	F	E	P	V	D	N	R	A	T	F	V	Q	V	C	N	R	Y	K
Query Conservation																					.
Alig confidence																					.										.
Template Conservation																															.
Template Sequence		F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	.	G	S	E	V	T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	A	A	V	E	L	R	L	R
Template Known Secondary structure																				T	T	T			S	S	T	T			.										T	T							T	T													T		S	S	T	T	T	S
Template Predicted Secondary structure																															.
Template SS confidence
		549	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.		.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.
		452	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		N	Y
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		628	.

---

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D